Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and annually updated a global strategy for asthma management and prevention that has formed the basis for many national guidelines. However, uptake of existing guidelines is poor. A major revision of the GINA r...eport was published in 2014, and updated in 2015, reflecting an evolving understanding of heterogeneous airways disease, a broader evidence base, increasing interest in targeted treatment, and evidence about effective implementation approaches. During development of the report, the clinical utility of recommendations and strategies for their practical implementation were considered in parallel with the scientific evidence.
more
Traumata werden definiert als Ereignisse von außergewöhnlicher Bedrohung, die nahezu bei jedem tiefgreifende Verzweiflung auslösen würde. Die „klassische“ Posttraumatische Belastungsstörung (PTBS) ist gekennzeichnet durch Intrusionen, Vermeidung und Hyperausal. Die komplexe Posttraumatische... Belastungsstörung (KPTBS) wird als eigenständige Diagnose in das ICD-11 aufgenommen und tritt als Folge von sich wiederholenden oder langandauernden traumatischen Ereignissen auf. Die KPTBS ist neben den Symptomen der PTBS durch Affektregulationsstörungen, negative Selbstwahrnehmung und Beziehungsstörungen gekennzeichnet. Aktuelle empirische Studien lieferten Hinweise für die Validität dieser Diagnose. Die Exposition in sensu mit dem traumatischen Ereignis steht im Mittelpunkt der als erfolgreich evaluierten Psychotherapien der PTBS und der KPTBS. Zur differenziellen Wirkung einzelner traumafokussierter Verfahren bei KPTBS können jedoch noch keine eindeutigen Empfehlungen ausgesprochen werden.
more
The Atlas of Palliative Care in the Eastern Mediterranean Region is the first systematic attempt to assess the status of resources, activities, and needs of palliative care in the region. It provides a comparative picture of the current state of palliative care in simple and clear graphics, utilisin...g texts, tables, figures and maps that reproduce information given by national palliative care leaders in the Eastern Mediterranean. This information is essential for the appropriate planning of the development of palliative care for this region.
more
In Kenya, the bacterial infections that contribute most to human disease are often those in which re-‐sistance is most evident. Examples are multidrug-‐resistant enteric bacterial pathogens such as typhoid, ... diarrhoeagenic Escherichia coli and invasive non-‐typhi salmonella, penicillin-‐resistant Streptococcus pneu-‐moniae, vancomycin-‐resistant enterococci, methicillin-‐resistant Staphylococcus aureus and multidrug-‐re-‐sistant Mycobacterium tuberculosis. Resistance to medicines commonly used to treat malaria is of particu-‐lar concern, as is the emerging resistance to anti-‐HIV drugs. Often, more expensive medicines are required to treat these infections, and this becomes a major challenge in resource-‐poor settings.
more
International Journal of Infectious Diseases 70 (2018) 121–130
https://doi.org/10.1016/j.ijid.2018.03.007
1201-9712/© 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://cr...eativecommons.org/licenses/by-nc-nd/4.0/).
more
Many countries are taking strict measures to prevent the spread of COVID-19 with lockdowns, curfews, and closure of public spaces and services. As a result of stress and uncertainty caused by these strict measures, women and girls are at even greater risk of violence at a time when their access to s...ervices is further reduced. With many people’s livelihoods and incomes significantly affected, together with movement restrictions, basic hygiene and menstruation items are unlikely to be prioritised.
10 April, 2020
more
Background: Understanding the natural course of child and adolescent posttraumatic stress disorder (PTSD) has significant implications for the identification of, and intervention for, at-risk youth. We used a meta-analytic approach to examine longitudinal changes in youth PTSD prevalence and symptom...s over the first 12 months posttrauma.
Journal of Child Psychology and Psychiatry57:8 (2016), pp 884–898
more
MEDBOX Issue Brief no. 7, Dec. 2020
Die Impfung gegen die Ausbreitung des SARS-CoV-2-Virus stellt einen Meilenstein in der Bekämpfung der Pandemie dar. Für den Erfolg der Impfung unabdingbar ist eine gute Kommunikation und Aufklärung der Bevölkerung. Im Folgenden sind einige Informationen zur I...mpfstrategie, Durchführung der Impfung, ethische Überlegungen, sowie Aufklärungsmaterialien in deutscher und englischer Sprache aufgelistet
more
DEMOGRAPHIC RESEARCH, VOLUME 36, ARTICLE 37, PAGES 1081-1108; PUBLISHED 5 APRIL 2017; http://www.demographic-research.org/Volumes/Vol36/37/; DOI: 10.4054/DemRes.2017.36.37
Wearing a face mask can help reduce the spread of COVID-19 in the community by reducing the release of respiratory droplets from asymptomatic / pre-symptomatic individuals or those with mild non-specific symptoms. The use of face masks for this purpose may be adopted to reduce the societal impact as...sociated with absence from work or healthcare pressures due to infection, or to protect vulnerable individuals in particular settings.
more
PLOS ONE 10(12): e0144040. doi:10.1371/journal.pone.0144040
DIAGNOSING PTSD IN CHILDHOOD | The following literature review addresses the developmental and domain-specific consequences of previous and current diagnostic criteria for posttraumatic stress disorder (PTSD) in pre-adolescent children. PTSD was introduced in 1980 to capture extreme responses follow...ing a traumatic event. I analyze the evolution of the disorder’s diagnostic criteria toward a more developmentally conscious structure. I also examine instances in which these criteria lack developmental consistency: (1) preschool PTSD is the only diagnostic subtype despite the fact that childhood development also differentiates traumatic expressions in older children from adolescents and adults; and (2) many of the PTSD epidemiological data that have been reanalyzed under the most recent (DSM-5) typology only refer to adolescent and adult samples although many researchers have
demonstrated that developmental alterations to DSM-IV and DSM-IV-TR criteria produce significantly higher prevalence rates in children.
more
Clinical Guidelines. Diagnosis and Treatment Manual.
PLOS ONE | www.plosone.org 1
December 2013 | Volume 8 | Issue 12 | e82027
This document provides a systematic approach in developing a coordinated, standardized, reliable, efficient, cost-effective, and sustainable specimen transport and referral system to support IVHD and VL testing networks. This document provides technical and programmatic recommendations on the approp...riate specimen storage and transportation of specimens for HIV VL and IVHD testing. Along with the national guidelines for specimen storage and transport, these standards should provide guidance on the creation or improvement of specimen referral networks and specimen transport systems. In addition, standard operating procedures (SOPs) targeting drivers and persons responsible for packing of specimens and results return are included in this document.
No publication year indicated in the document.
more
Drugs, Diagnostics, Vaccines, Preventive Technologies, Research toward a cure, and immune-based and gene therapies in development