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1
PLoS Negl Trop Dis 10(3): e0004530 -Published: March 2, 2016
This paper reviews the status of the Zika virus outbreak, including medical countermeasureoptions, with a focus on how the epidemiology, insect vectors, neuropathology, virology and immun
...
ology inform options and strategies available for medical countermeasure development and deployment.
Please download directly from the website Open Access: http://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0004530.PDF
more
This article was published on March 4, 2016, at NEJM.org.
DOI: 10.1056/NEJMoa1602412
Please download from the website: http://www.nejm.org/doi/full/10.1056/NEJMoa1602412
Les définitions de cas provisoires ont été élaborées dans un but de standardisation mondiale de la classification et de la notification des cas de maladie à virus Zika. L’OMS reverra régulièrement ces définitions de cas provisoires, au fu
...
r et à mesure que de nouvelles informations lui parviendront.
more
Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated from each other, and from other circulating arboviral
...
and non-arboviral pathogens, using laboratory tests. This document provides guidance on current testing strategies for Zika and dengue virus infections with updates to the previous interim guidance for laboratory testing for ZIKV, addressing pregnant and non-pregnant patients respectively, and incorporates current guidance for dengue virus diagnostic testing. The choice of laboratory assays and interpretation of test results require careful consideration of epidemiology, patient history, and limitations of existing diagnostic tests.
This interim guidance is for use by staff of laboratories testing for Zika and dengue virus infections and for clinical practitioners and public health professionals providing clinical management or surveillance.
more
This algorithm is addressed to laboratories
with established capacity(molecular, antigenic and/orserological) to detect dengue (DENV), Zika (ZIKV), and chikungunya(CHIKV) as part of the differential diagnosis for arborviruses. A BSL2 containment level is required to handle suspected samples.
The threat posed by Zika virus infection highlights the need to reinforce preparedness arrangements for mosquito-borne diseases in EU/EEA countries, especially for pathogens transmitted by Aedes aegypti and Aedes albopictus.
The aim of this documen
...
t is to highlight measures that can effectively reduce the risk of importation and local transmission of pathogens transmitted by Ae. aegypti and Ae. albopictus. The main diseases of concern in this context are Zika, dengue, chikungunya and yellow fever.
more
Zika Virus and Birth Defects — Reviewing the Evidence for Causality
Sonja A. Rasmussen, M.D., Denise J. Jamieson, M.D., M.P.H., Margaret A. Honein, Ph.D., M.P.H., and Lyle R. Petersen, M.D., M.P.H.
New England Journal of Medicine
(2016)
C3
published online April 13, 2016, DOI: 10.1056/NEJMsr1604338. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMsr1604338
Zika Virus
Lyle R. Petersen, M.D., M.P.H., Denise J. Jamieson, M.D., M.P.H., Ann M. Powers, Ph.D., and Margaret A. Honein, Ph.D., M.P.H.
New England Journal of Medicine
(2016)
C3
Review article published online March 30, 2016, DOI: 10.1056/NEJMra1602113. Please download directly from the webpage: http://www.nejm.org/doi/pdf/10.1056/NEJMra1602113
Zika virus is primarily transmitted by the Aedes species of mosquito which is also responsible for the spread of dengue, Chikungunya and yellow fever viruses. In most areas, the primary vector of these viruses is Aedes aegypti, with Aedes albopictus
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a proven or potential vector in some settings. Well-implemented vector control against Aedes using existing tools effectively reduces the transmission of viruses spread by these vectors. Pilot studies are being undertaken on new tools which have potential for future reductions in Aedes populations
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The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.
Zika Virus Infection - Step-by-Step Guide to Risk Communication and Community Engagement
recommended
This document provides Technical content on ZIKV, its manifestations, complications, modes of transmission, and prevention measures to be used in answering frequently asked questions and conveying messages in information and communication materials, community talks, press conferences, etc.
Interim Guidance
