Malaria
TOOLBOX

The MALARIA TOOLBOX is a comprehensive knowledge repository designed to support effective interventions aimed at tackeling Malaria worldwide. Malaria remains one of the most significant infectious diseases, posing a major public health challenge particularly in tropical and subtropical regions. Literature on malaria is essential for understanding its epidemiology, prevention strategies, diagnostic methods, and treatment options. 

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The malaria parasite develops both in humans and in the female Anopheles mosquitoes. The size and genetic complexity of the parasite mean that each infection presents thousands of antigens (proteins) to the human immune system.
Technical specifications series for submission to WHO prequalification: diagnostic assessment;TSS-3
​The CDC webpage on the clinical features of malaria outlines the disease's presentation, categorizing it into uncomplicated and severe forms, and emphasizes that prompt and accurate diagnosis and treatment can lead to a cure.
The fact sheet details transmission methods, symptoms, at-risk populations, diagnostic approaches, treatment options—including the use of artemisinin-based combination therapies (ACTs)—and preventive measures such as insecticide-treated nets (ITNs) and indoor residual spraying (IRS). It also dis ... more
El documento proporciona información básica sobre la malaria (paludismo), una enfermedad grave causada por un parásito que se transmite a través de la picadura de ciertos mosquitos, describe sus síntomas principales, cómo se diagnostica y trata, y ofrece recomendaciones de prevención, especia ... more
Der RKI-Ratgeber zur Malaria bietet umfassende Informationen über die durch Plasmodium-Parasiten verursachte Infektionskrankheit. Er richtet sich an medizinisches Fachpersonal und den Öffentlichen Gesundheitsdienst und behandelt Themen wie Infektionswege, Symptomatik, Diagnostik, Therapie und Prä ... more
The ECDC webpage on malaria provides an overview of the disease, emphasizing that while malaria is mostly travel-related in the EU/EEA, it remains a serious global health threat. It outlines symptoms, affected populations, travel-associated risks, and highlights the importance of prevention, surveil ... more
The article "Malaria – MSD Manual Professional Edition" provides a comprehensive overview of malaria, an infection caused by Plasmodium species. It describes symptoms such as fever, chills, and anemia, explains diagnostic methods like parasite detection in blood smears, and discusses treatment opt ... more
The AHO Malaria Fact Sheet gives a brief overview of malaria as a preventable and curable disease caused by Plasmodium parasites, mainly affecting sub-Saharan Africa. It highlights symptoms like fever and chills, notes vulnerable groups such as young children and pregnant women, and emphasizes the n ... more
​The CDC's "Malaria's Impact Worldwide" webpage provides an overview of malaria's global burden, highlighting that in 2022, there were approximately 249 million malaria cases and 608,000 deaths, predominantly among young children in sub-Saharan Africa. It emphasizes that nearly half the world's po ... more
Le site web de l'OMS intitulé « Paludisme » offre un aperçu complet du paludisme, une maladie potentiellement mortelle causée par des parasites du genre Plasmodium et transmise principalement par des piqûres de moustiques dans les pays tropicaux. Il fournit des informations sur les symptômes, ... more
The WHO website titled "Malaria" provides a comprehensive overview of malaria, a potentially fatal disease caused by Plasmodium parasites and primarily transmitted through mosquito bites in tropical countries. It offers information on symptoms, at-risk groups, preventive measures, and treatment opti ... more
El sitio web de la OMS titulado "Malaria" ofrece una visión completa de la malaria, una enfermedad potencialmente mortal causada por parásitos del género Plasmodium y transmitida principalmente por picaduras de mosquitos en países tropicales. Proporciona información sobre los síntomas, los gru ... more
The WHO website titled "Malaria" provides a comprehensive overview of malaria, a potentially fatal disease caused by Plasmodium parasites and primarily transmitted through mosquito bites in tropical countries. It offers information on symptoms, at-risk groups, preventive measures, and treatment opti ... more
The WHO website titled "Malaria" provides a comprehensive overview of malaria, a potentially fatal disease caused by Plasmodium parasites and primarily transmitted through mosquito bites in tropical countries. It offers information on symptoms, at-risk groups, preventive measures, and treatment opti ... more
La page « Paludisme » du Centre de collaboration nationale des maladies infectieuses (CCNMI) offre une synthèse complète sur cette maladie parasitaire transmise par les moustiques Anopheles. Elle aborde les causes, les symptômes similaires à ceux de la grippe, les complications possibles, ... more
List of annexes in Excel format:
Chapitre 50. Le texte traite du paludisme grave, une forme sévère du paludisme principalement causée par Plasmodium falciparum. Il explique les circonstances dans lesquelles le diagnostic doit être évoqué, notamment en cas de fièvre au retour d'une zone tropicale. Le document décrit les exam ... more
The webpage from Medicines for Malaria Venture (MMV) focuses on efforts to develop and provide child-friendly antimalarial treatments. It highlights the challenges of treating malaria in children, who are among the most vulnerable to the disease, and the need for safe, effective, and easy-to-adminis ... more

Pocket Manual for the Diagnosis and Treatment of Malaria

Olumese P., Al Zedjali M.S., Al-Mukhaini S. Ministry of Health, Sultanate of Oman - Department of Malaria Eradication (2025) C2
The "Pocket Manual for the Diagnosis and Treatment of Malaria", published by the Ministry of Health of the Sultanate of Oman, provides practical guidance for healthcare professionals on how to identify, manage, and treat malaria cases. It emphasizes parasitological confirmation before treatment, out ... more