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Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses to address
the many outstanding rese
...
arch questions. This systematic review aims to describe the characteristics and treatment practices of clinical studies in CD and assess the breadth and
availability of research data for the potential establishment of a data-sharing platform.
more
PLoS Negl Trop Dis 15(8): e0009697. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations still exist in our understanding of CD. Harnessing individual participant data (IPD) from studies could support more in-depth analyses t
...
o address the many outstanding research questions. This systematic review aims to describe the characteristics and treatment practices of clinical studies in CD and assess the breadth and availability of research data for the potential establishment of a data-sharing platform.
more
This report describes the results of the Lao People's Democratic Republic (LAO PDR) National WASH Survey 2021. The survey examined water, sanitation and hygiene (WASH) and waste management services, as well as climate resilience, in Lao PDR health-care facilities. The survey reveals that while
...
most facilities (70%) have basic water services, there are significant gaps in the delivery of sanitation, hygiene and health-care waste services, and few facilities are climate resilient, despite a majority being impacted by extreme weather events. Based on these results, the report presents a monitoring framework and national- and HCF-level measures to further enhance WASH services and climate resilience in the country.
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Strict storage recommendations for insulin are difficult to follow in hot tropical regions and even more challenging in conflict and humanitarian emergency settings, adding an extra burden to the management of people with diabetes. According to pharmacopeia unopened insulin vials must be stored in a
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refrigerator (2–8°C), while storage at ambient temperature (25–30°C) is usually permitted for the 4-week usage period during treatment. In the present work we address a critical question towards improving diabetes care in resource poor settings, namely whether insulin is stable and retains biological activity in tropical temperatures during a 4-week treatment period. To answer this question, temperature fluctuations were measured in Dagahaley refugee camp (Northern Kenya) using log tag recorders. Oscillating temperatures between 25 and 37°C were observed. Insulin heat stability was assessed under these specific temperatures which were precisely reproduced in the laboratory. Different commercialized formulations of insulin were quantified weekly by high performance liquid chromatography and the results showed perfect conformity to pharmacopeia guidelines, thus confirming stability over the assessment period (four weeks). Monitoring the 3D-structure of the tested insulin by circular dichroism confirmed that insulin monomer conformation did not undergo significant modifications. The measure of insulin efficiency on insulin receptor (IR) and Akt phosphorylation in hepatic cells indicated that insulin bioactivity of the samples stored at oscillating temperature during the usage period is identical to that of the samples maintained at 2–8°C. Taken together, these results indicate that insulin can be stored at such oscillating ambient temperatures for the usual four–week period of use. This enables the barrier of cold storage during use to be removed, thereby opening up the perspective for easier management of diabetes in humanitarian contexts and resource poor settings.
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This case study in Chile focused on the following two strategic levers of the WHO/UNICEF PHC Operational Framework during the implementation period 2022–2023: “Political Commitment and Leadership” and “Governance and Policy Frameworks”. Th
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is included examining how support from the three levels of the Organization (WHO headquarters, Pan American Health Organization (PAHO)/WHO Regional Office for the Americas and PAHO/WHO Chile Country Office) has been coordinated and operationalized. The case study also explored how, through these two strategic levers, catalytic actions have been planned and implemented in relation to other operational levers, in particular “Models of care”.
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This case study uses the Astana Primary Health Care (PHC) framework to explore the impact of the 2020–21 pandemic on primary health care in Kenya. While the pandemic exposed systemic challenges, such as limited testing capacity, an inadequate supp
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ly of PPE, and weak social protection, Kenya's health system also demonstrated notable adaptability. The response was largely hospital-centred, with PHC playing a secondary role. Nevertheless, innovations emerged on both the provider and consumer sides to maintain service delivery and access. The study emphasises the importance of building on these experiences to enhance emergency preparedness and develop a more robust and integrated health system.
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This research is one case in a study commissioned by the World Food Programme to investigate the participation of recipient community in the targeting and management of humanitarian food assistance in complex emergencies. The
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study involved a substantial desk review of existing documentation, and three weeks of field work in February and March 2008. The purpose of the study was to understand the ways in which participatory or community-based approaches to targeting have been attempted, within the definition of community-based targeting suggested by WFP. The study was not an evaluation of targeting methods, although some critical examination of targeting was necessary in order to understand the constraints on community participation.
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Dissertation submitted in part fulfilment of the requirements for a Masters degree at the Centre for International Health and Development (CIHD) at University College London (UCL) Institute of Child Health (ICH)
The user has given permission for the uploaded document to be reproduced and made publi
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cly available on the source website
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SAHARA-J: Journal
of Social Aspects of HIV/AIDS, 13:1, 1-7, DOI: 10.1080/17290376.2015.1123646
Nepal: Maternal Mortality and Morbidity Study 2008/2009
Pradhan A., Suvedi B.K., Barnett S., et al.
Government of Nepal, Ministry of Health and Population
(2010)
C1
Namibia National WISN Report 2015: A Study of Workforce Estimates for Public Health Facilities in Nambia
Titus, M., Hendricks, R., Ndemueda, J., McQuide, et al
Ministry of Health and Social Services, Republic of Namibia
(2015)
C2
This research report provides results from the study of living conditions
among people with disabilities in Lesotho. Comparisons are made
between disabled and non-disabled in household level and individual
level. Disability was defined as limitat
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ion to perform certain activities that
was measured according to the Washington City Group questions.
Results obtained in Lesotho are also compared to those obtained in
earlier studies carried out in Mozambique, Zambia, Namibia, Zimbabwe
and Malawi. The Lesotho study was undertaken in 2009-2010.
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This brief presents and addresses some of the challenges that prevent internally displaced persons with disabilities and other vulnerable population groups (elderly, injured persons, pregnant women, etc.) in camp settings from accessing humanitarian services in Iraq and impede on the development of
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an inclusive humanitarian response.
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Save the Children in Albania is establishing and strengthening structures and mechanisms which monitor and advocate for children’s rights, promote ways to protect children from all forms of exploitation and violence and also empower and support children and their representatives to meaningfully ad
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vocate for implementation of their rights and influence decisions that bring about changes in their future lives.
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Civil Society Organisations’ contribution towards community engagement to access and demand health services and encourage communities to practice appropriate health-seeking behaviour in Mon and Chin States
The following report is a study of 1 ... 4 villages under the Collective Voices project (November 2015-December 2017) in the states of Mon and Chin. The objectives of the study were:
(1) to explore Village Health Committee (VHC) members, Basic Health Staff (BHS), and community members’ perceptions on community engagement in seeking and demanding health care and
(2) to describe health-seeking behaviours relating to Maternal, Newborn, and Child Health and hygiene practices among target beneficiaries. more
The following report is a study of 1 ... 4 villages under the Collective Voices project (November 2015-December 2017) in the states of Mon and Chin. The objectives of the study were:
(1) to explore Village Health Committee (VHC) members, Basic Health Staff (BHS), and community members’ perceptions on community engagement in seeking and demanding health care and
(2) to describe health-seeking behaviours relating to Maternal, Newborn, and Child Health and hygiene practices among target beneficiaries. more
Living Conditions among People with Activity Limitations in Zambia: A National Representative Study.
This research report provides results from the study on living conditions among people with disabilities in Zambia. Comparisons are made between individuals with and without disabilities and also between households with and without a disabled family
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member. Results obtained in Zambia are also compared to those obtained in earlier studies carried out in Namibia, Zimbabwe and Malawi. The Zambian study was undertaken in 2005-2006.
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Living Conditions among People with Activity Limitations in Malawi. A National Representative Study.
This research report provides results from the study on living conditions
among people with disabilities in Malawi. Comparisons are made between
individuals with and without disabilities and also between households with and without a disabled fami
...
ly member. Results obtained in Malawi are also compared those obtained in earlier studies carried out in Namibia and Zimbabwe. The Malawian study was undertaken in 2003.
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