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Antidepressant medication in comparison with psychological treatment for moderate to severe depressive disorder
recommended

World Health Organization WHO (2015) C_WHO
Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommen ... more
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Pharmacological interventions for anxiety disorders in children and adolescents

World Health Organization WHO World Health Organization (2012) C_WHO
Q 12: In children and adolescents with anxiety disorders, what is the effectiveness and safety, considering system issues in low- and middle-income countries, of using pharmacological interventions in non-specialist settings?
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Second-generation antipsychotic medications for psychotic disorders (including schizophrenia)
recommended

World Health Organization WHO (2012) C_WHO
Q14. SCOPING QUESTION: In adults with psychotic disorders (including schizophrenia), what is the comparative effectiveness and safety of second-generation antipsychotic medications?
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The ASSIST-linked brief intervention for hazardous and harmful substance use

World Health Organization WHO (2010) C_WHO
Manual for use in primary care. This manual explains the theoretical basis and evidence for the effectiveness of brief interventions and assists primary health care workers in conducting a simple brief intervention for clients whose substance use i ... more
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A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge cluster randomised controlled trial in Neno Distr

Wroe, E.B.; Nhlema, B.; Dunbar, E.L. et al. BMJ Global Health (2021) CC
Background: Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of ... more
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The short-term effects of the implementation of the "Treat All" guidelines on ART service delivery costs in Namibia

Schutte, C.; Forsythe, S.; Fedes Mdala, J.; et al. (2020) CC2
PLoS ONE 15(1): e0228135. The introduction of “Treat All” (TA) has been promoted to increase the effectiveness of HIV/AIDS treatment by having patients initiate antiretroviral therapy at an earlier stage of their illness. The impact of introduc ... more
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Extending the WHO scheme for external quality assessment of nucleic acid amplification testing for monitoring antimalarial drug resistance: meeting report, 14 July 2023

World Health Organization WHO (2025) C_WHO
WHO recommends artemisinin-based combination therapies for treating uncomplicated malaria, alongside studies to monitor treatment effectiveness. Given the threat of antimalarial resistance, including partial resistance in several African countries, ... more
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State of the evidence 2021 - Modifications aiming to optimize acute malnutrition management in children under five

Action Against Hunger (2020) CC
This summary assesses the current state of evidence on each approach in tabular form, providing: the definition and objectives; evidence of effectiveness; operational considerations (e.g., training, staffing, and logistics); cost considerations and ... more
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World Health Organization Model List of Essential Medicines 24th List
recommended

World Health Organization WHO (2025) C_WHO
Essential medicines are those that satisfy the priority health care needs of a population. They are selected with due regard to disease prevalence and public health relevance, evidence of efficacy and safety and comparative cost-effectiveness. They ... more
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Sphere training materials for the Syria response

The Sphere Project (2016)
This version of the Sphere training pack was developed by the Sphere community to strengthen the capacity of humanitarian staff working in and around Syria. It seeks to help them professionalise and improve the effectiveness, quality and accountabil ... more
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WHO guidelines on use of medically important antimicrobials in food-producing animals

World Health Organization WHO (2017) C_WHO
These guidelines present evidence-based recommendations and best practice statements on use of medically important antimicrobials in food-producing animals, based on the WHO list of critically important antimicrobials for human medicine (WHO CIA List). These guidelines aim primarily to help preserve ... more
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Gender and One Health context analysis for HEAL

Eba, B.; Wieland B., Flintan F., et al. (2020) CC
The One Health approach can help achieve progress and promotes synergies on national and global priorities by generating synergies at the human-animal-environmental interface. While evidence is still scare, it is likely that the approach is highly cost-effective and improves ... more
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History, epidemiology and diagnostics of dengue in the American and Brazilian contexts: a review

Souza Salles, T.; T. da Encarnação Sá-Guimarães, E. Seam Lima de Alvarenga (2018) CC
Parasites & Vectors volume 11, Article number: 264 (2018) Dengue creates a staggering epidemiological and economic burden for endemic countries. Without a specific therapy and with a commercial vaccine that presents some problems relative to its full ... more
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Infection Control Assessment Tool: A Standardized Approach for Improving Hospital Infection Control Practices

South Africa's Dept. of Health; USAID; SIAPS (2010) C1
The ICAT is a simple and practical approach for assessing the adequacy of existing infection prevention and control practices and provides specific recommendations for improving practices and monitoring their effectiveness over time
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Disaster risk management systems analysis: A guide book

Baas, Stephan; Ramasamy, Selvaraju; Dey de Pryck, Jenny et al. Food and Agriculture Organization of the United Nations (FAO) (2008) C1
The guide book provides a set of tools and methods to assess existing structures and capacities of national, district and local institutions with responsibilities for Disaster Risk Management (DRM) in order to improve their effectiveness and the int ... more
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An Overview of Current Social Distancing Measures and Required Evidence for Determining Optimal Time for Relaxing Such Measures

Pan American Health Organization PAHO (2020) C_WHO
In the context of an unprecedented event such as the COVID-19 pandemic, at present, the effectiveness of stringent social distancing and international traffic-related measures in decreasing the rate of spread of SARS-CoV-2, and related mortality, is ... more
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Situation Analysis and Recommendations: Antibiotic Use and Resistance in Nepal

Nepal Public Health Foundation (2015) C2
Antibiotic resistance is no longer a concern for the distant future but is a pressing issue, both globally and in Nepal. As part of global effort to preserve the effectiveness of antibiotics, the Global Antibiotic Resistance P ... more
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TACKLING ANTIMICROBIAL RESISTANCE (AMR) TOGETHER Working Paper 5.0: Enhancing the focus on gender and equity

World Health Organization WHO (2018) C_WHO
This document aims to assist countries to take the first step towards better considering gender and equity issues in their efforts to tackle antimicrobial resistance (AMR), to inform the implementation of strategies in national action plans and contribute to improved reach and ... more
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Tracking Official Development Assistance for Reproductive Health in Conflict-Affected Countries

Patel P.; Roberts B.; Gury S. et al. PLOS Medecine (2009) CC
Reproductive health needs are particularly acute in countries affected by armed conflict. Reliable information on aid investment for reproductive health in these countries is essential for improving the efficiency and effectiveness of aid. The pur ... more
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استر استئصال شلل ةالأطفال للفتر 2026-2022

Global Polio Eradication Initiative GPEI; Organisation mondiale de la Santé (2022) C_WHO
The strengthened plan aims to achieve and sustain a polio-free world through a focus on implementation and accountability. Emphasis will be on cutting outbreak response times; increasing vaccine demand; transforming campaign effectiveness; working ... more