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Launch of the WHO Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019). Key findings
PLOS Glob Public Health 3(7): e0001132. https://doi.org/10.1371/journal. pgph.0001132 This paper proposes a framework for strategic communications for malaria governance that involves five key elements: knowing the audience, defining the message, designing a medium, identifying a messenger, and ... more
Malaria in children presents significant clinical challenges, with variations in presentation based on the malaria parasite involved and the child's underlying health conditions. The World Health Organization reports high incidence rates, particularly in sub-Saharan Africa, and emphasizes the import ... more
4th edition, Reference Manual
Presentation Current WHO guidance, strategies and lessons learnt of pre- and post-validation surveillance of NTDs
Anopheles stephensi is an invasive mosquito species which has been found spreading across Africa. While this species presents a new challenge for malaria control on the continent, its surveillance and management have been ongoing in Asia for many years. This document aims to summarize key lessons fr ... more
2nd edition. The purpose of this document is to present updated standardized protocols that P. falciparum-endemic countries can use to determine the prevalence of parasites with pfhrp2/3 gene deletions causing negative HRP2 RDT results among symptomatic falciparum patients. The findings should be us ... more
Clinical Pharmacology: Advances and Applications, 2025:17 29–47
Technical Report
Preferred product characteristics and clinical development considerations
Two malaria vaccines are currently WHO prequalified and recommended1 for use to prevent P. falciparum malaria in young children, the RTS,S/AS01 vaccine, currently manufactured by GlaxoSmithKline (GSK), and the R21/Matrix-M vaccine, manufactured by Serum Institute of India Pvt (SII)
The aim of this protocol is to support the conduct of entomological comparative efficacy assessments for vector control products and the associated non-inferiority analysis. This evidence is used to inform discussions within the guidelines development context as to whether a new vector control prod ... more
The purpose of the guideline is to provide information to stakeholders on the necessary requirements for a complete prequalification dossier for insecticide-treated nets (ITNs). Its aim is to establish the baseline for dossier requirements which are necessary to assess ITN products for the purposes ... more
Fragile Beginnings. The Fragile Beginnings series examines the growing body of research on the unique vulnerabilities of children: in utero and at birth, during infancy and childhood and throughout adolescence. Its purpose is to enable evidence-based advocacy and action on children’s environmental ... more
Thematic brief. Climate change and malaria are two defining challenges of our generation. Both affect disproportionately the poorest and the most vulnerable, especially in Africa, and may further jeopardize human wellbeing in the future
Note d'orientation
APMEN Case study
The National Strategic Plan for Malaria Elimination 2021–2025 outlines Bangladesh’s roadmap to achieve zero indigenous malaria cases by 2030, with an interim goal to reduce transmission to near-zero levels by 2025. The strategy builds upon earlier successes in malaria control and shifts focus to ... more
The framework recommends expanded coverage of malaria diagnostic and treatment services, intensified vector control to drive down transmission, strengthened malaria surveillance, and increased transborder collaboration, especially in terms of efforts to control the sale and use of artemisinin monoth ... more
According to the WHO, there were an estimated 251 million malaria cases (95% of global cases) and 579,414 malaria deaths (97% of global deaths) in African Union Member States in 2023. 76% of these deaths were children under the age of five.