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1
Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, with airway reversibility. Management of chronic inflammation with anti-asthma medication improves asthma control and quality of life. The aim of this journal is to provide an eviden
...
ce-based approach for chronic asthma management in young children and adolescents and provide guidance on the use of new asthma drugs in children.
For that, the South African Childhood Asthma Working Group (SACAWG) convened in January 2017. The asthma treatment task group reviewed the available scientific literature and international asthma treatment guidelines. The evidence was then graded according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system and recommendations were made based on scientific evidence and local context. Asthma management recommendations were made for children ˂6 years of age and older children and adolescents, as well as for stepping up and stepping down of therapy. This review does not include biologics or novel asthma drugs, which are covered in another CME article in this edition of SAMJ.
The final conclusions are that it is important to ensure good response, treatment and adherence, type of medication, device and checking of technique are all critical. Stepping up of therapy should be done only after ensuring good adherence and technique. Once therapeutic response is achieved, medication administration has to be stepped down to improve ease of use and avoid unnecessary side-effects.
more
Diagnosing asthma in children represents an important clinical challenge. There is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-diagnosis of asthma is frequent in children. A task force supported by the European Respiratory Society has developed these evidence
...
-based clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years using nine Population, Intervention, Comparator and Outcome (PICO) questions. The task force conducted systematic literature searches for all PICO questions and screened the outputs from these, including relevant full-text articles. All task force members approved the final decision for inclusion of research papers. The task force assessed the quality of the evidence using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.
The task force then developed a diagnostic algorithm based on the critical appraisal of the PICO questions, preferences expressed by lay members and test availability. Proposed cut-offs were determined based on the best available evidence. The task force formulated recommendations using the GRADE Evidence to Decision framework.
Based on the critical appraisal of the evidence and the Evidence to Decision framework, the task force recommends spirometry, bronchodilator reversibility testing and exhaled nitric oxide fraction as first-line diagnostic tests in children under investigation for asthma. The task force recommends against diagnosing asthma in children based on clinical history alone or following a single abnormal objective test. Finally, this guideline also proposes a set of research priorities to improve asthma diagnosis in children in the future.
more
Although asthma is very common, affecting 5–10% of the population, the diagnosis of asthma in adults remains a challenge in the real world, which results in both over- and under-diagnosis. A taskforce was set up by the European Respiratory Society to systematically review the literature on the dia
...
gnostic accuracy of tests used to diagnose asthma in adult patients and provide recommendations for clinical practice.
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This articel summarises the evidence base underpinning supported self-management for asthma. It provides clinicians with a practical approach to providing supported self-management for asthma and suggests an appropriate strategy for implementing supported self-management.
Asthma prevalence is increasing worldwide and surveys indicate that the majority of patients in developed and developing countries do not receive optimal care and are therefore not well controlled. The aim of these guidelines is to promote a better standard of treatment based on advances in the unde
...
rstanding of the pathophysiology and pharmacotherapy of asthma and to encourage uniformity in the management of asthma.
more
Time has seen management for Cystic Fibrosis (CF) advance drastically, most recently in the development of the disease-modifying triple combination therapy ivacaftor/tezacaftor/elexacaftor. There is currently limited evidence regarding both the global epidemiology of CF and access to this transforma
...
tive therapy - and therefore where needs are not being met. Therefore, this study aims to define gaps in access to CF treatment. The results show that a significant CF patient burden exists in countries where disease-modifying drugs are unavailable, and final figures are likely underestimates. This analysis shows the potential to improve rates of diagnosis and treatment for CF, so a higher percentage of patients receive the most effective triple combination treatment.
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Heliyon 2023 Oct 20;9(11):e21286. doi: 10.1016/heliyon.2023.e21286. This study conducted a systematic review of observational, community-based studies from 2013 to 2022, aiming to estimate the prevalence of prediabetes and its associated risk factors within the adult East African population. Twenty
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-one studies were analysed, revealing an overall prediabetes prevalence of 12.58%.
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The Early Warnings for All (EW4All) initiative aims to ensure universal protection from hazardous hydrometeorological, climatological and related environmental events through life-saving multi-hazard early warning systems, anticipatory action and resilience efforts by the end of 2027, as called for
...
by the United Nations Secretary-General António Guterres in 2022.
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Renforcement de la surveillance et du partage d’informations à l’échelle transfrontalière en Afrique
Le document intitulé « Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa » présente une stratégie coordonnée élaborée par Africa CDC afin d’améliorer la surveillance de la santé publique et la collaboration au-delà des frontières national
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es en Afrique. Il met en évidence le défi posé par le fait que les maladies infectieuses se propagent fréquemment au-delà des frontières en raison des mouvements de population, du commerce et des migrations, tandis que les systèmes de surveillance et les mécanismes de partage des données restent souvent centrés sur le niveau national et fragmentés.
Le cadre stratégique propose de renforcer la coordination régionale, d’harmoniser les systèmes de surveillance, d’améliorer le partage d’informations entre les pays et de développer les capacités des laboratoires ainsi que des ressources humaines. Il souligne également l’importance de la détection rapide des menaces sanitaires transfrontalières, des enquêtes conjointes sur les flambées épidémiques et d’une meilleure communication entre les États membres. Dans l’ensemble, le document vise à renforcer la préparation, les systèmes d’alerte précoce et la réponse collective aux menaces de santé publique sur le continent africain.
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O documento intitulado “Fortalecimento da Vigilância Transfronteiriça e do Compartilhamento de Informações na África” apresenta uma estratégia coordenada elaborada pelo Africa CDC para melhorar a vigilância em saúde pública e a colaboração além das fronteiras nacionais na Áfric
...
a. Ele destaca o desafio de que as doenças infecciosas frequentemente se propagam através das fronteiras devido ao movimento de pessoas, ao comércio e à migração, enquanto os sistemas de vigilância e os mecanismos de compartilhamento de dados permanecem muitas vezes centrados no nível nacional e fragmentados.
O quadro estratégico propõe fortalecer a coordenação regional, harmonizar os sistemas de vigilância, melhorar o intercâmbio de informações entre os países e desenvolver a capacidade dos laboratórios e dos recursos humanos. Também enfatiza a importância da detecção oportuna de ameaças sanitárias transfronteiriças, de investigações conjuntas de surtos e de uma comunicação aprimorada entre os Estados-membros. De modo geral, o documento visa reforçar a preparação, os sistemas de alerta precoce e a resposta coletiva às ameaças à saúde pública no continente africano.
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The UNDP webpage “Climate Information and Early Warning Systems” explains how climate information and early warning systems help countries and communities better prepare for and respond to climate-related hazards such as extreme weather events, floods, heatwaves and droughts. It describes UNDP
...
s approach to strengthening climate data collection, forecasting, communication and decision-making, as well as building partnerships and capacity to reduce risk, protect lives and support sustainable development in the face of a rapidly changing climate.
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L'objectif est de veiller à ce que les IPNS soient non seulement présents dans chaque État membre, mais qu'ils disposent également des cadres juridiques, des ressources et de l'expertise r à la réalisation de cet objectif, l'Africa CDC a élaboré un Plan de développement des instituts nation
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aux de santé publique en Afrique 2025-2027. L'objectif nécessaires pour mener efficacement les efforts de sécurité sanitaire en Afrique.
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The Healthy Living Toolkit is developed to educate refugees, immigrants, resettlement agencies, clinics, community based organizations, and other service providers on refugee health issues. The toolkit presents material in a culturally appropriate m
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anner and is intended to help health care-related professionals more effectively assist refugees and immigrants and reduce health disparities among these populations. The toolkit is available in multiple languages
more
Updated: 27 December 2013
Basic Indicators | Nutrition | Health | HIV/AIDS | Education | Demographic Indicators | Economic Indicators | Women | Child Protection | The Rate Of Progress | Adolescents | Disparities By Residence | Disparities By Hous
...
ehold Wealth | Early Childhood Development
more
Disability Inclusion | Published by Child Development & Rights and Sustainable Health on behalf of World Vision International.
Chapter 29: Refugees and Displaced Women:
Flight and Arrival,
Basic Needs,
Reproductive Health,
Mental Health,
Women as Leaders
This manual aims to provide an overview of this subject to health care professionals, paramedics and other voluntary services involved in health care promotion
Antibiotic resistance has been recognized as a major global health threat and optimizing prescribing is one of the most effective measures to preserve the effectiveness of antibiotics. The quality of prescribing depends mostly on those pres
...
cribers belonging to clinical medical specialties having direct contact with patients. These doctors, who comprise the majority of antibiotic prescribers,undergo long-term undergraduate and postgraduate training that shapes their professional knowledge and behaviour
J Antimicrob Chemother2019;74: 3611–3618doi:10.1093/jac/dkz375 Advance Access publication 3 September 2019
more
The COVID-19 pandemic has had an unprecedented impact on health care systems that, in many instances, worsened the already existing assistance gaps. When it comes to Latin America and Central America, this challenge adds to the consequences mass mob
...
ilizations have had in recent years, which have exceeded the national capacities to provide prompt assistance and social protection, particularly in the health care field. This pandemic has a direct impact on people on the move since the movement restriction policies and the lockdown and social distancing measures have reduced their ability to insert themselves into economic activities that were already precarious in many cases. Consequently, they have less access to food, housing, medicines and other essential consumer goods, and fewer possibilities of getting to their countries of destinati
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GO VIRAL! helps protect you against COVID-19 misinformation. You’ll learn about some of the most common ways false and misleading information about the virus are spread. Understanding these tricks allows you to resist them the next time you come across them online. Scientists who worked with us on
...
the development of GO VIRAL! found that playing the game significantly improves people’s ability to spot misinformation about COVID-19.
The recommended age for GO VIRAL! is 15+. Although the game has received a PEGI-age rating of 3 (i.e., the game has been deemed suitable for persons age 3 and up), the game does include some themes that may be interpreted as sensitive, especially to people under the age of 15. If you are unsure, always ask for parental consent.
Spread the word – fight the spread of misinformation by challenging your friends and family to GO VIRAL!
Available in different languages
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