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The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project has conducted a multi-year, multi-country study that provides stark insights on the under-reported depth of the antimicrobial resistance (AMR) crisis across Africa and lays out urgent policy recommendations to addr
...
ess the emergency.
MAAP reviewed 819,584 AMR records from 2016-2019, from 205 laboratories across Burkina Faso, Cameroon, Eswatini, Gabon, Ghana, Kenya, Malawi, Nigeria, Senegal, Sierra Leone, Tanzania, Uganda, Zambia, and Zimbabwe. MAAP also reviewed data from 327 hospital and community pharmacies and 16 national-level AMC datasets.
more
The Mapping Antimicrobial Resistance and Antimicrobial Use Partnership (MAAP) project has conducted a multi-year, multi-country study that provides stark insights on the under-reported depth of the antimicrobial resistance (AMR) crisis across Africa and lays out urgent policy recommendations to addr
...
ess the emergency.
MAAP reviewed 819,584 AMR records from 2016-2019, from 205 laboratories across Burkina Faso, Cameroon, Eswatini, Gabon, Ghana, Kenya, Malawi, Nigeria, Senegal, Sierra Leone, Tanzania, Uganda, Zambia, and Zimbabwe. MAAP also reviewed data from 327 hospital and community pharmacies and 16 national-level AMC datasets.
more
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus (DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with cardiovascular death. Diabetes is associated with a 2- to 4-fold increased risk for heart failure (HF). Moreover, HF patients wit
...
h DM have a worse prognosis than those without DM. Diabetes can cause myocardial ischemia via micro- and macrovasculopathy and can directly exert deleterious effects on the myocardium. Hyperglycemia, hyperinsulinemia, and insulin resistance can cause alterations in vascular homeostasis. Then, reduced nitric oxide and increased reactive oxygen species levels favor inflammation leading to atherothrombotic progression and myocardial dysfunction. The classification, diagnosis, and treatment of HF for a patient with and without DM remain the same. Until now, drugs targeting neurohumoral and metabolic pathways improved mortality and morbidity in HF with reduced ejection fraction (HFrEF). Therefore, all HFrEF patients should receive guideline-directed medical therapy. By contrast, drugs modulating neurohumoral activity did not improve survival in HF with preserved ejection fraction (HFpEF) patients. Trials investigating whether sodium-glucose cotransporter-2 inhibitors are effective in HFpEF are on-going. This review will summarize the epidemiology, pathophysiology, and treatment of HF in diabetes.
more
Pharmaceuticals 2024, 17(6), 691; https://doi.org/10.3390/ph17060691
The ILO has joined forces with Gallup to carry out a groundbreaking global survey covering 50 countries that sheds further light on the causes of the persistence of HIV-related stigma and discrimination in the world of work.
Technology and digital tools are transforming everyday life, opening new opportunities for women and girls—but they are also being weaponized to harass, threaten, and silence them online. Technology-facilitated violence against women and girls (TF VAWG) is now a defining challenge for gender equal
...
ity, closely linked to violence offline and shaped by deep-rooted discrimination.
more
The UNICEF Gender Equality Action Plan, 2026–2029 provides the road map
for the organization’s key commitments to advancing gender equality and the
empowerment of all girls and women, anchored in the UNICEF Strategic Plan,
2026–2029.
Strategic Advice
The companion Handbook on Humanitarian Access presents the normative framework pertaining to humanitarian access in situations of armed conflict, and therefore serves as a useful reference source for humanitarian practitioners on the normative framework.
This initial version of the Field Manual –
...
labeled Version 1.0 – was elaborated by Conflict Dynamics International in collaboration with the FDFA and the UN Office for the Coordination of Humanitarian Affairs (OCHA).
Development of the structured approach and guidance contained in this Manuel
involved a consultation process which included bilateral meetings with humanitarian organizations, regional consultation events and consultations during several field visits, including dedicated field missions
more
Gender-based violence and child protection among Syrian refugees in Jordan, with a focus on early marriage
UNWomen
(2013)
Findings from this report reveal that, rates of early marriage are high, a significant percentage of children contribute to the household’s income or are its main source of income, and restrictions on the mobility of women and girls constrain their participation in social and economic activities a
...
nd their access to basic services. As the overwhelming majority of refugees do not have paid employment and rely mainly on aid and dwindling family resources, the more the situation of displacement is prolonged the greater the likelihood of higher rates of child labour for boys and early marriage for girls.
more
Report commissioned by the IASC Inter-Agency Humanitarian Evaluations Steering Group as part of the Syria Coordinated Accountability and Lessons Learning Initiative
Recovering from the Ebola Crisis
Magdy Martínez-Solimán; Abdoulaye Mar Dieye; Izumi Nakamitsu et al.
United Nations, The World Bank, European Union and African Development Bank
(2015)
Full Report.
In response to a call by the United Nations Secretary-General and the Governments of Guinea, Liberia and Sierra Leone, an international team conducted an Ebola Recovery Assessment. The aim was to contribute towards laying the foundation for short-, medium- and long-term recovery while
...
the medical emergency response continues to tackle the epidemic. This report is a contribution to ongoing efforts by the Governments of Guinea, Liberia and Sierra Leone to design their national Ebola virus disease recovery strategies
more
Disaster Recovery Toolkit
Too important to fail - addressing the humanitarian financing gap
High-Level Panel on Humanitarian Financing Report to the Secretary-General
World Humanitarian Summit
(2016)
C1
Sphere for Monitoring and Evaluation
recommended
Sphere Unpacked
