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The document provides comprehensive guidelines on cholera outbreak management, including prevention, diagnosis, and treatment. It emphasizes rapid response measures, the importance of rehydration therapy (oral and intravenous), and public health int
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erventions such as water sanitation, hygiene promotion, and disease surveillance to control the spread of cholera in affected communities. It is designed as a resource for healthcare providers and public health officials.
more
The second ECDC/EFSA/EMA joint report on the integrated analysis of antimicrobial consumption (AMC) and antimicrobial resistance (AMR) in bacteria from humans and food-producing animals addressed data obtained by the Agencies’ EU-wide surveillance
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networks for 2013–2015. AMC in both sectors, expressed in mg/kg of estimated biomass, were compared at country and European level. Substantial variations between countries were observed in both sectors. Estimated data on AMC for pigs and poultry were used for the first time. Univariate and multivariate analyses were applied to study associations between AMC and AMR. In 2014, the average AMC was higher in animals (152 mg/kg) than in humans (124 mg/kg), but the opposite applied to the median AMC (67 and 118 mg/kg, respectively). In 18 of 28 countries, AMC was lower in animals than in humans. Univariate analysis showed statistically-significant (p < 0.05) associations between AMC and AMR for fluoroquinolones and Escherichia coli in both sectors, for 3rd- and 4th-generation cephalosporins and E. coli in humans, and tetracyclines and polymyxins and E. coli in animals. In humans, there was a statistically-significant association between AMC and AMR for carbapenems and polymyxins in Klebsiella pneumoniae. Consumption of macrolides in animals was significantly associated with macrolide resistance in Campylobacter coli in animals and humans. Multivariate analyses provided a unique approach to assess the contributions of AMC in humans and animals and AMR in bacteria from animals to AMR in bacteria from humans. Multivariate analyses demonstrated that 3rd- and 4th-generation cephalosporin and fluoroquinolone resistance in E. coli from humans was associated with corresponding AMC in humans, whereas resistance to fluoroquinolones in Salmonella spp. and Campylobacter spp. from humans was related to consumption of fluoroquinolones in animals. These results suggest that from a ‘One-health’ perspective, there is potential in both sectors to further develop prudent use of antimicrobials and thereby reduce AMR.
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Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the endemic areas in sub-Saharan Africa. HAT transmission l
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ast soared in the late 1990s, triggering a renewed, coordinated and very successful control effort. In this paper, we present achievements towards HAT elimination, with a focus on the WHO road map targets for 2020. In particular, reported cases continue to decline, from over 30,000 cases per year at the turn of the century to 663 cases in 2020. Despite the impact of the COVID-19 pandemic, HAT surveillance was largely sustained, and the network of health facilities able to diagnose and treat the disease further expanded. Looking to the future, the World Health Organization (WHO) set bold new targets for HAT in its 2021–2030 road map for NTDs, namely: the elimination of transmission of gambiense HAT, which occurs in western and central Africa, and the elimination as a public health problem of rhodesiense HAT, which is found in eastern and southern Africa. The strong commitment of national health authorities and the international community will be essential if these goals are to be achieved.
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This UNHCR guidance note provides comprehensive recommendations for the prevention and control of malaria in refugee settings worldwide. Aligned with the WHO Global Technical Strategy for Malaria, it outlines strategies to ensure access to effective prevention, diagnosis and treatment, implement sus
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tainable transmission reduction measures and strengthen surveillance systems. The document is intended as a practical resource for humanitarian actors, public health officials and partners involved in planning and implementing malaria programmes in refugee operations, with the aim of reducing malaria-related morbidity and mortality among vulnerable populations.
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The emergence of SARS-CoV-2 has significantly altered the epidemiology of other infectious diseases, making investigations into its co-infection with malaria particularly relevant in endemic regions. This review examines the epidemiological, incubation and clinical features of the two diseases, high
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lighting the diagnostic challenges and strategies for accurate detection. Emerging immunological and genetic evidence indicates that prior exposure to malaria may reduce the severity of outcomes of SARS-CoV-2 infection through mechanisms involving ACE2 downregulation, TLR signalling, T-cell activation and upregulation of coinhibitory receptors. Additionally, potential control measures are discussed, including vaccine development, the repurposing of antimalarial drugs, the exploration of natural products, innovations in bioinsecticides, and the strengthening of electronic disease surveillance. These insights provide valuable guidance for clinical management and public health policy, while emphasising the need for continued research into the complex interactions between SARS-CoV-2 and malaria.
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The NIAID Pandemic Preparedness Plan describes the strategy of the National Institute of Allergy and Infectious Diseases (NIAID) to strengthen research and development for future pandemic threats. The plan focuses on identifying and studying viruses with the potential to cause epidemics or pandemics
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and developing medical countermeasures such as vaccines, therapeutics and diagnostics. A key concept is the research on “prototype pathogens,” which represent virus families that may cause future outbreaks, allowing scientists to prepare tools and knowledge in advance. The document also outlines the importance of surveillance, epidemiological research, technological innovation, clinical trials and international collaboration to enable a faster and more effective response to emerging infectious diseases. Overall, the plan aims to improve scientific preparedness so that new health threats can be detected earlier and controlled more rapidly.
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Epidemiology of type 2 diabetes in India
Pradeepa, R.; Mohan, V.
Indian Journal of Ophthalmology 69(11):p 2932-2938, November 2021.
(2021)
CC2
The burden of diabetes is high and increasing globally, and in developing economies like India, mainly fueled by the increasing prevalence of overweight/obesity and unhealthy lifestyles. The estimates in 2019 showed that 77 million individuals had diabetes in India, which is expected to rise to over
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134 million by 2045. Approximately 57% of these individuals remain undiagnosed. Type 2 diabetes, which accounts for majority of the cases, can lead to multiorgan complications, broadly divided into microvascular and macrovascular complications. These complications are a significant cause for increased premature morbidity and mortality among individuals with diabetes, leading to reduced life expectancy and financial and other costs of diabetes leading to profound economic burden on the Indian health care system. The risk for diabetes is largely influence by ethnicity, age, obesity and physical inactivity, unhealthy diet, and behavioral habits in addition to genetics and family history. Good control of blood sugar blood pressure and blood lipid levels can prevent and/or delay the onset of diabetes complications. The prevention and management of diabetes and associated complications is a huge challenge in India due to several issues and barriers, including lack of multisectoral approach, surveillance data, awareness regarding diabetes, its risk factors and complications, access to health care settings, access to affordable medicines, etc. Thus, effective health promotion and primary prevention, at both, individual and population levels are the need of the hour to curb the diabetes epidemic and reduce diabetes-related complications in India
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This manual has been developed to guide rapid risk assessment of acute public health risks from any type of hazard in response to requests from Member States of the World Health Organization (WHO).
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The manual is aimed primarily at national departments with health-protection responsibilities, National Focal Points (NFPs) for the International Heath Regulations (IHR) and WHO staff. It should also be useful to others who join multidisciplinary risk assessment teams, such as clinicians, field epidemiologists, veterinarians, chemists, food-safety specialists.
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This document provides countries with recommendations for structuring a public health entomology laboratory network. The document will help countries to identify their areas of need and determine how the entomology network can be strengthened, espec
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ially in the context of a decentralized health system. The recommendations also consider the different degrees of development and different entomological research needed to support disease prevention and control activities.
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The webpage introduces the “Health Cluster Coordination” channel on World Health Organization’s OpenWHO platform, focusing on training and resources for coordinating
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health-cluster operations in humanitarian emergencies. It outlines how participants can learn about setting up and managing health clusters, establishing collaboration among partners, and ensuring effective service delivery in crisis settings.
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The WHO Health Security Learning Platform (HSLP) is an online training hub that provides courses and toolkits to strengthen countries’ capacities in public-health preparedness, emergency response,
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and implementation of the International Health Regulations (IHR). It offers self-paced modules and practical training materials on topics such as outbreak response, points-of-entry management, One Health, and laboratory preparedness, helping health professionals build essential skills for global health security.
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Renforcement de la surveillance et du partage d’informations à l’échelle transfrontalière en Afrique
Le document intitulé « Strategic Framework for Strengthening Cross-Border Surveillance and Information Sharing in Africa » présente une stratégie coordonnée élaborée par Africa CDC afin d’améliorer la
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surveillance de la santé publique et la collaboration au-delà des frontières nationales en Afrique. Il met en évidence le défi posé par le fait que les maladies infectieuses se propagent fréquemment au-delà des frontières en raison des mouvements de population, du commerce et des migrations, tandis que les systèmes de surveillance et les mécanismes de partage des données restent souvent centrés sur le niveau national et fragmentés.
Le cadre stratégique propose de renforcer la coordination régionale, d’harmoniser les systèmes de surveillance, d’améliorer le partage d’informations entre les pays et de développer les capacités des laboratoires ainsi que des ressources humaines. Il souligne également l’importance de la détection rapide des menaces sanitaires transfrontalières, des enquêtes conjointes sur les flambées épidémiques et d’une meilleure communication entre les États membres. Dans l’ensemble, le document vise à renforcer la préparation, les systèmes d’alerte précoce et la réponse collective aux menaces de santé publique sur le continent africain.
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Register on the Website for free to receive the weekly briefing
This implementation plan sets out a series of programmatic objectives, activities and outcomes for malaria surveillance strengthening in Myanmar over the next two years. This period represents a key phase as the National Malaria Control Programme (N
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MCP) strives to build on recent achievements in strengthening core surveillance operations.
more
La surveillance épidémiologique est un processus continu de collecte, d’analyse et de diffusion d’informations pour la prise d’actions de riposte. Les activités de surveillance épidémiolo
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gique sont mises en œuvre au Sénégal selon la stratégie SIMR (Surveillance Intégrée de la Maladie et Riposte) et suivant le RSI (version 2005). Cependant, très souvent les données de surveillance des maladies, surtout au niveau communautaire, ne sont pas toujours bien enregistrées, notifiées et analysées. Aujourd’hui, les maladies transmissibles émergentes et ré-émergentes comme la maladie à virus Ebola (MVE), constituent une menace importante pour la santé et le bien-être de nos communautés.
more
Guide du Formateur en Communication des Acteurs Communautaires sur la Surveillance Epidémiologique Intégrée
recommended
La Surveillance épidémiologique est un processus continu de collecte, d'analyse et de diffusion d'informations pour la prise d'actions de riposte. Les activités de surveillance épidémiologique
...
sont mises en oeuvre au Sénégal selon la stratégie SIMR (Surveillance Intégrée de la Maladie et Riposte) et suivant le RSI (Version 2005). Cependant, très souvent les données de surveillance des maladies, surtout aux niveau communautaire, ne sont pas toujours bien enregistrées, notifiées et analysées.
Aujourd'hui, les maladies transmissibles emergentes et ré-émergentes comme la maldie à Virus Ebola (MVE), constituent une menace importante pour la santé et le bien-êtres de nos communautés. Fort heureusement, les interventions de lutte et de prévention sont bien connues pour certaines.
Il en résulte que des opportunités pour prendre et mettre en place des mesures de riposte appropriées de santé publique pour sauver des vies existens et doivent être clairement indentifiées. Pour cela, il s'avère nécessaire de former de manière adéquate les acteurs communautaires et de mettre en place un système perfomant de surveillance intégrée des maladies aux niveau communautaire soutenu par une communication appropriée avec les populations aussi bien en milieu urbain que rural.
more
Guide Technique pour la Surveillance Intégrée de la Maladie et la Riposte dans la Région Africaine
recommended
Troisième edition
19 August 2022. A monkeypox case investigation form (CIF) has been designed as a tool for Member States and researchers to conduct in-depth epidemiological investigation of suspected, probable and confirmed cases of monkeypox. This form allows to collect data prospectively or retrospectively for bot
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h cases and their contacts. The full form is meant to serve as a tool for in-country use and the data are not required to be reported to WHO.
more
Le présent guide opérationnel sert de feuille de route pour la surveillance et les interventions en matière de mortalité maternelle et périnatale dans les milieux cliniques et politiques, comme décrit dans les deux guides de référence de l
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Organisation mondiale de la santé (OMS) intitulés : Surveillance des décès maternels et riposte – Directives techniques – Prévention des décès maternels – Informations au service de l’action («Guide SDMR», 2013) et Pour que chaque enfant compte : audit et examens des mortinaissances et des décès néonatals» (2016).
Ces deux guides proposent des approches fondées sur l’utilisation de données de qualité sur les soins de santé pour mettre un terme aux décès maternels, aux mortinaissances et aux décès néonatals évitables.
more
