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Vaccines are designed to give you immunity without the dangers of getting the disease. It’s common to experience some mild to moderate side effects when receiving vaccinations. This is because your immune system instructs your body to increase blo
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od flow so more immune cells can circulate, and it raises your body temperature to kill the virus. Vaccines help protect us against disease and feeling mild or moderate side effects after receiving one is a sign that the vaccine and our immune system is working.
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This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series.
Vaccines are supported by decades of medical research.
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They work by preparing the body's own immune system to recognise and defend against a specific disease. The volume of information available about vaccination can be overwhelming, so it’s important to talk through the topic.
Available in different languages
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WHO and Psyon Games have joined forces to launch a new tower defense game called the Antidote COVID-19 to turn complex, scientific information into a fun learning experience. During the course of the game, players will learn about their immune system
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, pathogens, vaccines and how to protect themselves from COVID-19.
The game comes at a critical point of the pandemic where misinformation is hindering COVID-19 vaccine acceptance and adherence to other public health measures due to fear, mistrust and doubt. By putting players in the driver’s seat, the game urges everyone to play a role in fighting harmful misinformation online, and learning and sharing the facts from trusted sources of information.
The game starts just before the pandemic begins. The player is recruited to halt the spread of SARS-COV-2, the virus that causes COVID-19, by developing vaccines and helping the human immune system fight off the virus. Based on real events, this online adventure takes the player to the frontline of science, ultimately providing lifesaving information in the palms of their hands.
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The aim of this survey was to provide evidence-based recommendations to improve the overall quality of Emergency Medical Services (EMS) in Ukraine, with a special focus on the oblasts (administrative regions) of Luhansk and Donetsk. The objectives were to: describe the EMS
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system in Ukraine with regards to its capacity, utilization and efficiency across selected geographic regions and catchment areas to assess the utilization and outcomes of current prehospital EMS care; identify perceived needs in key areas based on input from local stakeholders, including EMS providers, hospital-care providers administrative staff and patients; create an evaluation model of EMS performance; and provide recommendations for improvements to the EMS system in Ukraine.
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Resource platform.
The Global Atlas of medical devices (GAMD) provides global, regional and country data on availability of:
national policy on health technology
regulation of medical devices
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health technology assessment national unit
health technology management
use of medical devices nomenclature system
national lists of priority medical devices
high cost medical equipment.
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Rabies is a vaccine-preventable, zoonotic, viral disease affecting the central nervous system. Once clinical symptoms appear, rabies is virtually 100% fatal. In up to 99% of cases, domestic dogs are responsible for rabies virus transmission to human
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s. Yet, rabies can affect both domestic and wild animals. It spreads to people and animals via saliva, usually through bites, scratches or direct contact with mucosa (e.g. eyes, mouth or open wounds). Children between the age of 5 and 14 years are frequent victims.
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Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease. Infection occurs when filarial parasites are transmitted to humans through mosquitoes. Infection is usually acquired in childhood causing hidden damage to the lymphatic
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system.
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The International Conference on Population and Development in 1994 set targets for donor funding to support family planning programmes, and recent initiatives such as FP2020 have renewed focus on the need for adequate funding to rights-based family planning. Disbursements supporting family planning
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disaggregated by donor, recipient country and year are not available for recent years. We estimate international donor funding for family planning in 2003–13, the period covering the introduction of reproductive health targets to the Millennium Development Goals and up to the beginning of FP2020, and compare funding to unmet need for family planning in recipient countries. We used the dataset of donor disbursements to support reproductive, maternal, newborn and child health developed by the Countdown to 2015 based on the Organization for Economic Cooperation and Development Creditor Reporting System.
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This document provides practical guidance on planning and implementing next-generation sequencing (NGS) technology for characterization of Mycobacterium tuberculosis complex (MTBC) bacteria. The aim is to detect mutations associated with drug resistance in the context of a surveillance
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system for tuberculosis (TB).
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The WHO Global Respiratory Syncytial Virus (RSV) Surveillance page describes a World Health Organization initiative under the Global Influenza Programme to monitor RSV infections worldwide. It explains that WHO uses the existing Global Influenza Sur
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veillance and Response System (GISRS) to collect standardized epidemiological and laboratory data on RSV, in order to understand patterns such as seasonality, disease burden, and age groups at highest risk, especially in young children. The surveillance system aims to support countries in tracking RSV activity, improve detection and laboratory capacity, and generate evidence that can guide public health policies, including the use of vaccines and preventive measures. Overall, the text emphasizes building a global platform for RSV surveillance integrated with influenza monitoring to inform better respiratory virus control strategies.
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This Mobile user guidance is aimed at supporting implementation of EWARS in a box, WHO’s electronic early warning, alert and response system in emergencies. This guidance fulfills a long felt need to have an easy to use resource with step-by-step
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instructions in establishing EWARS in a box, facilitating field epidemiologists, surveillance officers and emergency responders.
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In the area of nutrition and HIV, children deserve special attention because of their additional needs to ensure growth and development and their dependency on adults for adequate care. It was therefore proposed to first develop guidelines for children and thereafter consider a similar approach for
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other specific groups.
The content of these guidelines acknowledges that wasting and undernutrition in HIV-infected children reflect a series of failures within the health system, the home and community and not just a biological process related to virus and host interactions. In trying to protect the nutritional well-being or reverse the undernutrition experienced by infected children, issues of food insecurity, food quantity and quality as well as absorption and digestion of nutrients are considered. Interventions are proposed that are practical and feasible in resource-poor settings and offer a prospect for clinical improvement.
The guidelines do not cover the feeding of infants 0 to 6 months old, because the specialised care in this age group is already addressed in other WHO guidelines and documents.
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Laboratory diagnosis of Buruli ulcer
recommended
A manual for health care providers.
This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists w
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orking on this disease, the manual details the exact procedures to follow when performing a range of diagnostic tests. Recommended procedures, intended for use throughout the health system, are presented at levels appropriate for peripheral, district and central services and in accordance with the varying resources, skills and equipment typically found in countries where Buruli ulcer is endemic.
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WHO Pharmacovigilance indicators: a practical manual for the assessment of pharmacovigilance systems
This manual provides a practical method for determining the pharmacovigilance indices. It is designed to be simple and can be understood by any worker in pharmacovigilance without formal training in monitoring and evaluation. Pharmacovigilance as a medical discipline is crucial in preventing medicin
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e-related adverse effects in humans, promoting patient safety, and the rational use of medicines. The indicators proposed in this manual are based on the expected functions of pharmacovigilance centres as described in the WHO Mimimum Requirements for a Functional Pharmacovigilance System (1) (see Annex 1 of the manual).
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Antimicrobial resistance (AMR) occurs when disease-causing pathogens are able to withstand the killing or suppressing power of antimicrobial medicines. This phenomenon increases the global burden of infectious diseases and strains health systems.Thi
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s course aims to improve the learner's awareness and understanding of the basic principles of AMR, the impact AMR has on individuals and society, and why it is a major public health concern.
A complementary course, Antimicrobial Resistance (Part 2), describes interventions that address the multiple factors contributing to AMR across the health system.
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Notable progress has also been made on other key health indicators such as reducing maternal, infant and child deaths and malnutrition, increasing immunization coverage, eliminating infectious diseases such as polio and reducing the incidence of mal
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aria, tuberculosis and diarrhoeal diseases.
But despite such substantial progress, the country now faces new and emerging new challenges such as the rising burden of noncommunicable diseases, increased risks associated with disasters, environmental threats and health emergencies during disease outbreaks including the COVID-19 pandemic that is a serious public health threat to Bangladesh. To establish a resilience system for future potential pandemics, the national capacity for emergency preparedness and early response to health emergencies needs to be bolstered considerably.
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This document is a situation report (#6) from October 2, 2017, describing the cholera outbreak in Yemen. By October 1, 2017, there were 777,229 suspected cholera cases and 2,134 deaths across 22 of Yemen's 23 governorates. The response involves WASH partners providing hygiene supplies and water trea
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tment, health cluster partners operating treatment centers, and communication campaigns reaching over 16 million people. Major challenges include limited supplies, security risks hindering access to affected communities, a weakened health system with over 55% of facilities closed or partially functional, and difficulties importing medicines and medical supplies. Children under 18 represent 60% of cases, while people over 60 report the highest death rates.
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RBC/IHDPC/ EID Division | November2011 - The aim of the standard operating procedures is to guide health care providers and public health
experts from various levels of the
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health system in the implementation of enhanced surveillance of meningococcal meningitis.
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The aim of the Annual Inspection Report is to present findings of public sector health establishments inspected by the OHSC to monitor compliance with the National Core Standards (NCS) during the 2016/2017 financial year in South Africa.
The NCS de
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fine fundamentals for quality of care based on six dimensions of quality: Acceptability,Safety, Reliability, Equity, Accessibility, and Efficiency.
The NCS structured assessment tools were used to collect data during inspections across the seven domains namely: Patient Rights; Patient Safety, Clinical Governance and Clinical Care; Clinical Support Services; Public Health; Leadership and Governance; Operational Management and Facilities and Infrastructure. A total of 851 routine inspections were conducted with 201 of these facilities re-inspected. Inspection data was captured on District Health Information System (DHIS) data entry forms and exported for analysis to Statistical Analysis Software (SAS) version 9.4.
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The guidelines presented in this document are designed to provide a useful resource for healthcare professionals involved in clinical case management. They were developed taking into consideration services provided at different levels within the health
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system and resources available. These guidelines are intended to standardize care at both tertiary and secondary levels of service delivery across different socio economic stratifications of our society.
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