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Publication Years
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These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
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ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
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In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
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al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
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The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access
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to integrated services. Based on these pillars, the AEVT plan guides galvanizing political advocacy for the last mile toward the elimination of vertical transmission of HIV, syphilis and HBV in Africa by 2030
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The family-centered approach to reaching every child living with HIV. This report examines the structural barriers impeding equitable access to HIV testing, treatment initiation and long-term adherence – essential elements for sustaining health and well-being for children, adolescents and young wo
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men. Rooted in socio-cultural norms, gender disparities and systemic inequalities, these barriers obstruct progress by perpetuating stigma, limiting healthcare access and destabilizing treatment continuity, stalling efforts toward the 10-10-106 and 95-95-957 targets.
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The document Integrated Disease Surveillance and Response Technical Guidelines, Booklet Four: Sections 8 and 9 (Third Edition, 2019) provides guidance for strengthening public health surveillance and response systems in the WHO African Region. It focuses on monitoring, supervision, evaluation, and f
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eedback mechanisms to improve the performance and quality of Integrated Disease Surveillance and Response (IDSR) systems. The text outlines key surveillance core functions—such as case detection, reporting, data analysis, outbreak investigation, preparedness, response, and feedback—and introduces indicators to measure system effectiveness, including timeliness, completeness, and data quality. Additionally, it discusses the implementation of electronic IDSR (eIDSR) to enhance real-time reporting and outbreak management. Overall, the booklet aims to strengthen early detection, rapid response, and health security capacity across all levels of the health system.
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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
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ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
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Paving the Way for One Health: Highlights of the Global Programme Pandemic Prevention and Response, One Health
Haensel L., Argote K., Stübel E.
Deutsche Gesellschaft für Internationale Zusammenarbeit GIZ
(2024)
CC
The document “Paving the Way for One Health: Highlights of the Global Programme Pandemic Prevention and Response, One Health” presents the work and achievements of the global programme implemented by the German development agency GIZ to strengthen pandemic prevention using the One Health approac
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h. The report highlights how collaboration between the human health, animal health, and environmental sectors can help detect and prevent zoonotic diseases before they spread. It describes activities carried out in partner countries, such as improving surveillance systems, strengthening laboratory capacities, supporting cross-sector cooperation, and building the skills of health professionals. The document also showcases practical examples and project results that demonstrate how integrated One Health strategies contribute to better preparedness and more effective responses to future health threats. Overall, the report illustrates how international cooperation and interdisciplinary approaches can reduce the risk of pandemics and improve global health security.
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The World report on promoting the health of refugees and migrants: Monitoring progress on the WHO global action plan provides the first global baseline for assessing implementation of the 2019-2030 WHO Global Action Plan on Promoting the Health of Refugees and Migrants (GAP). Building on the 2022 Wo
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rld report on the health of refugees and migrants, it examines how countries are integrating refugee and migrant health into broader public health, migration governance, development, and universal health coverage (UHC) agendas.
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Incorporating epidemics risk in the INFORM Global Risk Index
Poljanšek K., Marin-Ferrer M., Vernaccini L., Messina L.
European Commission – Joint Research Centre (JRC)
(2018)
C2
The document focuses on integrating epidemic risk into the INFORM Global Risk Index, a tool used to assess and compare crisis and disaster risks across countries. It explains how epidemics can significantly impact vulnerability and hazard exposure, and therefore should be systematically included in
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risk assessments. The report outlines methods, indicators, and data sources for incorporating epidemic risk into the index, improving its ability to capture health-related threats. Overall, the document aims to enhance risk analysis and support better preparedness, planning, and decision-making by providing a more comprehensive understanding of global risks.
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Guía de manejo clínico del paciente grave con fiebre amarilla
recommended
New
Las recomendaciones aquí presentadas fueron elaboradas a partir de una síntesis sistemática de la evidencia disponible y adoptan un enfoque pragmático, orientado a facilitar su aplicación en escenarios clínicos complejos y de alta demanda. Su desarrollo se fundamenta en los principios de la me
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todología GRADE, lo que garantiza transparencia en la evaluación de la evidencia y claridad en la formulación de las recomendaciones.
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This guideline provides global, evidence-informed recommendations on a number of specific issues related to the management of severe acute malnutrition in infants and children, including in the context of HIV.
