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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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WHO country cooperation strategy 2014-2018, Myanmar

World Health Organization (WHO), Country Office for Myanmar (2014) C_WHO

The strategic priorities of the CCS 2014–2018 are:
(1) Strengthening the health system.
(2) Enhancing the achievement of communicable disease control targets.
(3) Controlling the growth of the noncommunicable disease burden.
(4) Promoting health throughout the life course.
... more

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The compound impact of extreme weather events and COVID-19

Walton D., Arrighi J., et al. IFRC - International Federation of Red Cross (2021) C2

From the start of the COVID-19 pandemic until August 2021, extreme weather events have affected at least 139.2 million people and killed at least 17,242 people in at least 433 unique events. These figures are certainly an underestimate, as they do not include estimates of numbers of people affected ... more

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Encopresis - spanish

A. von Gontard IACAPAP (2017) C2

Transtornos del desarrollo Capítulo C.5 Edición en español Editor: Nieves Hermosín Carpio Traducción: María Carballo Novoa, María Esteban Arenós

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Mass Casualty Management Systems. Strategies and guidelines for building health sector capacity

Health Action in Crisis Word Health Organization (2007)

Disaster planning - organization and administration. 2.Emergency medical services - methods. 3.Emergency medical services - organization and administration. 4.Emergencies. 5.Health policy. 6.Health facilities.7.Guidelines.

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Guidelines for antiretroviral therapy in Ghana

Ghana AIDS Commission (2010) C1

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Preparing for and responding to global health emergencies

Cochrane Convenes (2022) C1

Learnings from the COVID-19 evidence response and recommendations for the future. Reflections and recommendations from the evidence synthesis community.

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Novel vaccination approaches to prevent tuberculosis in children

J. A. Triccas, C. Counoupas Pneumonia; BioMed Central (2016) CC

Review Triccas and Counoupas Pneumonia (2016) 8:18; DOI 10.1186/s41479-016-0020-z

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Assessment of Learning Disabilities: Cooperation between Teachers, Psychologists and Parents

Tuija Aro and Timo Ahonen Niilo Mäki Institute (2011) C2

African edition

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Report of the United Nations High Commissioner for Human Rights on the situation of Human rights in the Bolivarian Republic of Venezuela (A/HRC/41/18)

UN Human Rights Council (2019) C1

(Advance unedited version)

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Management of febrile seizures

World Health Organization WHO (2012) C_WHO

Q3: Can febrile seizures (simple or complex) be managed at first or second level care by non-specialist health care providers in low and middle income country settings? What is the role of diagnostic tests in the management of febrile seizures by non-specialists in low and middle income settings? Fo... more

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The treatment of epilepsy in developing countries: where do we go from here?

Robert A. Scott, Samden D. Lhatoo & Josemir W.A.S. Sander WHO (2001) C_WHO

Bulletin of the World Health Organization, 2001, 79 (4)

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WHO Country Cooperation Strategy 2017-2021, Zambia

World Health Organization WHO, Regional Office for Africa (2017) C_WHO

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Improving Cultural Competence - QUICK GUIDE FOR CLINICIANS

SAMSHA (2016) C1

Treatment Improvement Protocol (TIP) Series No. 59 This Quick Guide is based entirely on information contained in TIP 59, published in 2014. No additional research has been conducted to update this topic since publication of TIP 59. | This Quick Guide provides succinct, easily accessible informatio... more

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Invisible Wounds. The impact of six years of war on the mental health of Syria’s children

Save the Children (2017) C1

“The children are psychologically crushed and tired. When we do activities like singing with them, they don’t respond at all. They don’t laugh like they would normally. They draw images of children being butchered in the war, or tanks, or the siege and the lack of food.” Teacher in the... more

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National Community Health Worker Strategy in Zambia

Ministry of Health, Zambia (2010) C1

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WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update
recommended

World Health Organization WHO (2021) C_WHO

6 July 2021. The “WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update” is the latest document replacing the one issued in 2020. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included in the... more

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WHO's Response to the Ukraine Crisis. Interim Report. February to June 2022

World Health Organization (WHO) (2022) C_WHO

The military offensive by the Russian Federation in Ukraine which began February 2022 has triggered one of the world’s fastest-growing displacement and humanitarian crisis, with geopolitical and economic ripples felt across the globe. The ongoing war has caused large-scale disruptions to the deliv... more

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Towards a Human Rights-Based Approach to Migration: Training Guide

UN Office of the High Commissioner for Human Rights OHCHR (20023) CC

This training guide is designed to enable participants to understand the human rights perspective on migration, and how human rights laws and standards can be operationalized to make migration safer and an empowering experience for all. It provides an introduction to related principles and issues an... more

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The West African Initiative for Climate-Smart Agriculture (WAICSA)

Chiriac, D.; et al. GIZ; Bloomberg Philatrhopies, IFAG; et al. (2019) CC

The Lab identifies, develops, and launches sustainable finance instruments that can drive billions to a low-carbon economy. The 2019 Global Lab Cycle targets four specific sectors across mitigation and adaptation: blue carbon in marine & coastal ecosystems; sustainable agriculture for smallholde... more

WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update recommended

WHO consolidated guidelines on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update
recommended