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Antimicrobial resistance in Africa: a systematic review

Tilahun Tadesse, B., E. A. Ashley, S. Ongarello et al. BMC Infectious Diseases (2017) C2

Internationally, there is a growing concern over antimicro-bial resistance (AMR) which is currently estimated to ac-count for more than 700,000 deaths per year worldwide. If no appropriate measures are taken to halt its pro-gress, AMR will cost approximately 10 million lives andabout US$100 trillion... more

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Guidance on Emergency Expedited Regulatory Authorisation and Access to COVID-19 Vaccines in Africa

African Union; Africa CDC Centres for Disease Control and Prevention (2021) C1

Taking the whole of Africa approach to fighting the COVID-19 pandemic has and will continue to require coordinated efforts from multiple stakeholders from across the continent. Africa CDC would like to acknowledge the deep partnership and continued support of AUDA-NEPAD, AVAREF, WHO AFRO, the Bill a... more

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Situational Brief: Report on East Africa and Horn of Africa

Martini M, M. Abdiker Lancet Migration (2020) CC

The COVID-19 pandemic poses an additional and critical challenge in a fragile humanitarian context, where the population is already highly vulnerable and lives in often overcrowded settlements where distancing is impossible, and with limited access to basic health services and hygiene. Further sprea... more

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Cross-Border Female Genital Mutilation in East Africa

UNFPA ESARO UNFPA; UNICEF (2022) CC

In East Africa, the trend in cross-border FGM puts at risk the progress achieved in eliminating the practice. The only way we can reach zero FGM by 2030 is by concerted and immediate action to address all aspects of FGM. This policy brief highlights the cross-border dimension of FGM (Ethiopia, Keny... more

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Indigenous Healing of War Affected Children in Africa

Green, E.C. & Honwana, A. World Bank (WB) (1999) C2

IK Notes No. 10 July 1999 | IK Notes reports periodically on Indigenous Knowledge (IK) initiatives in Sub-Saharan Africa. It is published by the Africa Region's Knowledge and Learning Center as part of an evolving IK partnership between the World Bank, communities, NGOs, development institutions and... more

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WHO Guidelines for Malaria

World Health Organisation (WHO) (2024) C_WHO

The conditionality of this recommendation is largely driven by the current higher unit cost of pyrethroid-PBO ITNs compared to pyrethroid-only LLINs and therefore the uncertainty of their cost-effectiveness. Furthermore, as PBO is less wash-resistant than pyrethroids, its bioavailability declines ... more

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Determinants Of Coital Frequency Among Married Women In Central African Republic: The Role Of Female Genital Cutting

Stewart H.; L. Morrison; R. White Journal of Biosocial Science (2002) C1

Journal of Biosocial Science / Volume 34 / Issue 04 / October 2002, pp 525 - 539 DOI: DOI:10.1017/S0021932002005254, Published online: 24 September 2002 This paper examines determinants of one aspect of sexual behaviour – coital frequency – among 2188 married women in the Central African Re... more

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Mpox Surveillance Reporting Protocol for African Union Member States

Africa Center for Disease Control and Prevention CDC (2024) CC

On 13 August 2024, the Africa Centres for Disease Control (Africa CDC) declared the multi-country mpox outbreak a public health emergency of continental security, with strong recommendations to improve surveillance and vaccine deployment in all AU Member States. On 14 August 2024, the WHO Director-G... more

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West Africa Desert Locust Crisis Appeal (May–December 2020)

Food and Agriculture Organization of the United Nations FAO; reliefweb (2020) C2

Recent forecasts by the Food and Agriculture Organization of the United Nations (FAO) have indicated a risk of locust invasion in West Africa from June 2020. From East Africa, some swarms could reach the eastern part of the Sahel and continue westwards from Chad to Mauritania. Surveillance and co... more

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WHO Pharmaceutical Situation Assessment – Level II – Health Facilities Services Ghana

Daniel Kojo Arhinful Ministry of Health, Ghana (2009) C1

This field study to assess the pharmaceutical situation was undertaken in Ghana in May-June 2008 using a standardized methodology developed by the World Health Organization. The study assessed medicines availability and affordability, geographical accessibility, quality and r... more

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WHO Level II household survey to measure access to and use of medicines in Ghana

Daniel Kojo Arhinful Ministry of Health, Ghana (2011) C1

This field study to measure access to and use of medicines was undertaken in GHANA in May-June 2008. The study assessed information on the socio-economic level of households, and access to and use of medicines for acute and chronic conditions as well as opinions and perceptio... more

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WHO Methodology for Point Prevalence Survey on Antibiotic Use in Hospitals

World Health Organization WHO (2019) C_WHO

Version 1.1. The WHO protocol has been adapted to resource-limited settings and builds on existing methodologies from the European Centre for Disease Prevention and Control (ECDC), the Global PPS project from University of Antwerp, the US Centers for Disease Control and Prevention (CDC), and the Med... more

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Cancer in sub-Saharan Africa
recommended

Ngwa, W.; et al. Lancet Oncology Commission (2022) C2

Lancet Oncol 2022; 23: e251–312Published OnlineMay 9, 2022 https://doi.org/10.1016/S1470-2045(21)00720-8 In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality. Without rapid interventions, data estimates show a major increase in cancer mo... more

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Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ...is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more

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Covid-19 RCCE Strategies for Cross-Border Movement in Eastern and Southern Africa

Social Science in Humanitarian Action (2020) CC

Key Considerations This brief focuses on cross-border movement in Eastern and Southern Africa (ESA) and its implications for development of risk communication and community engagement (RCCE) strategies aimed at preventing transmission of COVID-19 in the ESA region. Given the extensive risk of cross... more

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Research and Evaluation Agenda for HIV and Maternal Health in sub-Saharan Africa

Kendall, Tamil; Danel, Isabella (2014) C1

Women and Health Initiative Working Paper No. 1. Women and Health Initiative
Improving maternal health in the context of the sub-Saharan African HIV epidemic requires greater understanding of the relationships between HIV disease and maternal morbidity and mortality, integrated and effective resp... more

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Africa CDC Consortium for COVID-19 Vaccine Clinical Trials (CONCVACT)

African Union; Africa CDC Centres for Disease Control and Prevention (2020) C1

August 2020, The Africa Joint Continental Strategy for COVID-19 is underpinned by the need to limit transmission, prevent deaths and reduce associated harms. Participation by African nations in clinical trials is an essential step to ensure that sufficient data is generated on the safety and efficac... more

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Coronavirus in Sub-Saharan Africa - How africans in 12 nations are responding to the COVID-19 outbreak

GeoPoll (2020) C2

The spread of COVID-19 poses a challenge for emerging markets such as those in Africa and Latin America. While governments around the world are suffering from a shortage of ventilators, hospital beds, and personal protective equipment, availability of these items is already extremely limited in some... more

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Guidelines for using the APCA African Children’s Palliative Outcome Scale

African Palliative Care Association APCA (2012) C2

In the absence of a such a measure, and building on the success of developing the APCA African Palliative Outcome Scale (POS) for adults, the African Palliative Care Association has developed the APCA African Children’s POS. The tool has been validated across diseases, countries, settings and ... more

Cancer in sub-Saharan Africa recommended

Cancer in sub-Saharan Africa
recommended