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Report of the fifth WHO stakeholders meeting on gambiense and rhodesiense human African trypanosomiasis elimination

World Health Organization WHO (2023) C_WHO
WHO convened the fifth stakeholders meeting on the elimination of HAT due to infection with Trypanosoma brucei gambiense (g-HAT) and Trypanosoma brucei rhodesiense (r-HAT) in Geneva, Switzerland, on 7–9 June 2023. The meeting was held again in person after the coronavirus disease (COVID-19) pandem... more
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Criteria and procedures for the verification of elimination of transmission of "T. b. gambiense" to the human population in a given country

World Health Organization WHO (2023) C_WHO
Having established the goal of eliminating transmission of gambiense human African trypanosomiasis (g-HAT) to humans, the HAT-e-TAG considered which elements should be developed to assess this goal.
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Human African trypanosomias: Number of new reported cases of human African trypanosomiasis (T.b. gambiense) 2023

World Health Organization WHO (2023) C_WHO
Database with maps and country-specific numbers
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Human African Trypanosomiasis (sleeping sickness): Current knowledge and future challenges

Papagni, R.; et al. (2023) CC
Front. Trop. Dis. , 09 May 2023 Sec. Neglected Tropical Diseases Volume 4 - 2023 | https://doi.org/10.3389/fitd.2023.1087003
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Reported cases of chronic African trypanosomiasis, 2022

Our World in Data (2023) CC
The number of reported cases of chronic African trypanosomiasis (sleeping sickness). The disease is caused by parasites that are spread by tsetse flies and otherinsects. The disease is typically fatal if not treated.
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Target product profile for a gambiense human African trypanosomiasis test to identify individuals to receive widened treatment

World Health Organization WHO (2022) C_WHO
The development of this target product profile (TPP) was led by the WHO Department of Control of Neglected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was form... more
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Vector control and the elimination of gambiense human African trypanosomiasis

World Health Organization WHO (2022) C_WHO
The main purpose of the meeting was to review tsetse control tools, activities and their contribution to the elimination of gHAT and the monitoring thereof. Seven endemic countries provided reports on recent and ongoing vector control interventions at the national level (Angola, Cameroon, Côte d’... more
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African Trypanosomiasis (African Sleeping Sickness; Human African Trypanosomiasis; HAT)

Chelsea, M.; and W.A. Petri (2022) CC
MSD Manual Professional Version
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African Trypanosomiasis (African Sleeping Sickness; Human African Trypanosomiasis; HAT) Patient Information

Chelsea, M.; and W.A. Petri (2022) CC
MSD Manual Consumer Version
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Human African trypanosomiasis cases diagnosed in non-endemic countries (2011– 2020)

Franco. J.R.; G. Cecchi, G. Priotto, et al. (2022) CC
PLoS Negl Trop Dis 16(11): e0010885. https://doi.org/10.1371/journal.pntd.0010885 HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and surveillance must be maintained to contribute to WHO’s elimination goals. Early detection is particularly important as it co... more
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Target product profile for a test for rhodesiense human African trypanosomiasis diagnosis usable in peripheral health facilities

World Health Organization WHO (2021) C_WHO
The development of this target product profile (TPP) was led by the WHO Department of Control of Ne- glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was... more
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An atlas of tsetse and animal African trypanosomiasis in Zimbabwe

Shereni, W.; L. Neves, R. Argilés, et al. (2021) CC
Parasites Vectors 14, 50 (2021). https://doi.org/10.1186/s13071-020-04555-8
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Human African Trypanosomiasis (Sleeping Sickness). The Road to Elimination Revisited—Achievements and Remaining Challenges

Burri, E. MDPI (2020) CC
Printed Edition pdf
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African Sleeping Sickness (Trypanosomiasis) | Causes, Symptoms and Treatment

JJ Medicine (2019) CC
Video. Lesson on African Trypanosomiasis (African Sleeping Sickness): Causes, Symptoms and Treatment. African Trypanosomiasis is caused by parasitic protozoa from the genus trypanosoma. Trypanosoma protozoa are carried in the tsetse fly, and when a person is bitten by a tsetse fly, trypomastigotes ... more
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Sleeping Sickness - an introduction to African Trypanosomiasis

Let's learn about bugs (2017) C2
Video. Human African Trypanosomiasis, also known as sleeping sickness is a devastating parasitic disease. It is a neglected tropical disease affecting communities in Africa. In this video we take a look at the disease, how it presents and and ways to control it.
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Human African trypanosomiasis. Seminar

Büscher P., Cecchi G., Jamonneau V. et al (2017) C2
The Lancet Volume 390, Issue 10110p2397-2409November 25, 2017. Human African trypanosomiasis (HAT), also called sleeping sickness, is a parasitic infection that almost invariably progresses to death, unless treatment is provided. HAT caused devastating epidemics during the 20th century. Thanks to ... more
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Trypanosomiase humaine africaine : lutte et surveillance

World Health Organization WHO (2014) C_WHO
Un comité OMS d’experts sur la trypanosomiase humaine africaine (THA) : lutte et surveillance, s’est réuni à Genève (Suisse), du 22 au 26 avril 2013. Le Dr H. Nakatani, sous-directeur général pour le VIH/SIDA, la tuberculose, le paludisme et les maladies tropicales négligées, a ouvert la... more
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The Atlas of HAT

World Health Organization WHO (2008) C_WHO
In February 2008, WHO launched the Atlas of HAT as a collaborative initiative with the Food and Agriculture Organization of the United Nations (FAO), within the framework of the Programme Against African Trypanosomosis (PAAT). The Atlas database is built by the systematic collection of information a... more