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The widespread termination of US government contracts and PEPFAR stop work orders have had a devastating impact on access to HIV prevention. To find out more about what happened and understand the ongoing impacts in detail, click on the link
This brief from Audere and AVAC explains how artificial intelligence (AI) can support the HIV field by expanding reach, enhancing prevention, and improving care.
The Lancet HIV. Volume 12, Issue 10e712-e721October 2025. This article from The Lancet HIV estimates the impact of the PEPFAR funding pause for PrEP on HIV infections in sub-Saharan Africa.
2025 is the first year of this century where child deaths will increase. But we can stop this reversal before it becomes a trend, even in a time of tight budgets. With proven solutions and next-generation innovations that do more with less, we can save millions of children's lives, protect the pro ... more
2025 ist das erste Jahr dieses Jahrhunderts, in dem die Kindersterblichkeit steigen wird. Aber wir können diese Umkehrung stoppen, bevor sie zu einem Trend wird, selbst in Zeiten knapper Budgets. Mit bewährten Lösungen und Innovationen der nächsten Generation, die mit weniger mehr erreichen, k ... more
2025 sera la première année de ce siècle où le nombre de décès d'enfants augmentera. Mais nous pouvons mettre fin à ce renversement de tendance avant qu'il ne devienne une norme, même en période de restrictions budgétaires. Grâce à des solutions éprouvées et à des innovations de nou ... more
2025 es el primer año de este siglo en el que aumentará la mortalidad infantil. Pero podemos detener este retroceso antes de que se convierta en una tendencia, incluso en una época de presupuestos ajustados. Con soluciones probadas e innovaciones de última generación que permiten hacer más c ... more
Policy information sheet
This issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse ... more
Recent suspensions and reductions in official development assistance (ODA) have posed significant challenges to HIV programme continuity in several countries. These funding disruptions have impacted people living with HIV and other vulnerable populations who rely on these essential services, like a ... more
These targets define what is required to reach the global goal of ending AIDS as a public health threat by 2030 and will be proposed for adoption by United Nations Member States at the 2026 United Nations High-Level Meeting on HIV/AIDS. Finalization of the recommended targets will be followed by the ... more
The Private Sector Engagement Strategy on HIV, STIs and TB is a is a guide that is both comprehensive and focused, and it is to be used by businesses and corporations to actively participate in the HIV, STIs and TB and Noncommunicable diseases (NCDs) response. The goal of this strategy is to devel ... more
Why we need Targets for 2025. 1.2020 Fast Track targets will soon elapse; 2. Current UNAIDS strategy concludes in 2021; 3. Informs possible UN General Assembly Special Session on AIDS in 2021; where a new Political Declaration on AIDS would be adopted; 4. Informs the strategies of other organisatio ... more
Disability inclusive shelter programming enables persons with disabilities to contribute more to their communities, participate more in consultations and decision-making, and facilitate their own protection. The key concepts include: Disability inclusive shelter programming is both a process and an ... more
This Guidance was developed in response to the increase in HIV-related human rights crises and the shrinking civic space for rights-related responses to HIV in recent years across the world. This document builds upon existing guidance documents, offering updated guidance for country-based United Nat ... more
This report is the first of a series of biennial progress reports on the implementation of the Global health sector strategies on HIV, viral hepatitis and sexually transmitted infections for the period 2022–2030. It draws attention to areas of progress and gaps in preparation for the mid-term revi ... more
Technical Brief
Providing quality, stigma-free services is essential to equitable health care for all and achieving global HIV goals and broader Sustainable Development Goals related to health. Every person has the right to the highest attainable standard of physical and mental health. Countries have a legal obliga ... more
The indicators and questions in this document are designed for use by national AIDS programmes and partners to assess the state of a country’s HIV and AIDS response, and to measure progress towards achieving national HIV targets. Countries are encouraged to integrate these indicators and questions ... more
Human Rights Fact Sheet Series