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Malaria in Children

Temu A., Kabyemela G. (2025) C2
Malaria in children presents significant clinical challenges, with variations in presentation based on the malaria parasite involved and the child's underlying health conditions. The World Health Organization reports high incidence rates, particularly in sub-Saharan Africa, and emphasizes the import... more
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Malaria amongst children under five in sub-Saharan Africa: a scoping review of prevalence, risk factors and preventive interventions

Sarfo, J.O.; M. Amoadu, P.Y. Kordorwu, et al. (2023) CC2
Eur J Med Res 28, 80 (2023). https://doi.org/10.1186/s40001-023-01046-1. Africa has a higher burden of malaria-related cases and deaths globally. Children under five accounted for over two-thirds of all malaria deaths in sub-Saharan Africa (SSA). This scoping review aims to map evidence of the preva... more
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National Guidelines for the Treatment of Malaria, South Africa 2019

National Department of Health, South Africa (2019) C1
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WHO technical consultation on preferred product characteristics for drugs used in malaria chemoprevention

World Health Organization WHO (2022) C_WHO
On 15–16 December 2020, WHO and the Medicines for Malaria Venture co-convened a technical consultation to consider the preferred product characteristics (PPCs) for drugs used in malaria chemoprevention. The main goal of the technical consultation was to agree on the most important PPCs for drugs t... more
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Gaps in service Utilization and service provision: an analysis of DHS and SPA Malaria data from Malawi, Senegal, and Tanzania

C. Taylor, A. Linn, W. Wang, and H. Moussa (2018) C2
Barriers to the prompt and effective diagnosis and treatment of malaria exist at both the community and health facility level. Household surveys measure malaria case management at the population level with standard indicators that assess treatment-seeking behavior, access to diagnostic testing, and ... more
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National Guidelines for the Treatment of Malaria - 2019

South African Malaria Elimination Committee (SAMC) National Department of Health South Africa (2019) CC
These guidelines are based on the 3rd Edition of the WHO Guidelines (Published 2015) World Health Organization’s Guidelines for the treatment of malaria. Additional literature surveys have been undertaken. Factors that were considered in the choice of therapeutic options included effectiveness, sa... more
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WHO Guidelines for Malaria

World Health Organisation (WHO) (2024) C_WHO
The conditionality of this recommendation is largely driven by the current higher unit cost of pyrethroid-PBO ITNs compared to pyrethroid-only LLINs and therefore the uncertainty of their cost-effectiveness. Furthermore, as PBO is less wash-resistant than pyrethroids, its bioavailability declines ... more
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Liberia Malaria Indicator Survey 2016

National Malaria Control Program (NMCP) [Liberia], Ministry of Health (MOH), Liberia Institute of Statistics and Geo-Information Services (LISGIS), and ICF (2017) C2
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Malaria vaccines. Summary of the WHO position paper

World Health Organization WHO (2024) C_WHO
WHO position paper on malaria vaccines, Weekly Epidemiological Record 10 May 2024
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Malaria “chemoprevention and vaccination strategies” for children living in endemic areas of Africa: a review

Nambatya, W.; M. Ocan, B. Robberstad , et al. (2025) CC
Front. Malar. 3:1336324. doi: 10.3389/fmala.2025.1336324
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Seasonal malaria chemoprevention with sulfadoxine–pyrimethamine plus amodiaquine in children: a field guide

World Health Organization WHO (2023) C_WHO
2nd edition. This second edition builds on the experience of more than 10 years of SMC deployment, and reflects changes introduced in the WHO guidelines for malaria, 3 June 2022. The goal of this publication is to share these best practices to improve SMC implementation, coverage, and monitoring and... more
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Preventive malaria treatment among school-aged children in sub-Saharan Africa: a systematic review and meta-analyses

Cohee, LM.; C. Opondo, S. E Clarke, et al. (2020) C1
Lancet Glob Health 2020 Published Online October 22, 2020 https://doi.org/10.1016/S2214-109X(20)30325-9
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Spatial distribution and determinants of asymptomatic malaria risk among children under 5 years in 24 districts in Burkina Faso

Ouédraogo M., Samadoulougou S., Rouamba T. et. al. Malaria Journal (2018) C2
Malaria Journal (2018) 17:460 https://doi.org/10.1186/s12936-018-2606-9 In malaria endemic countries, asymptomatic cases constitute an important reservoir of infections sustaining transmission. Estimating the burden of the asymptomatic population and identifying areas with elevated risk is import... more
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Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double- blind, randomised, phase 3 trial

Datoo, M.S.; A. Dicko, H.Tinto, et al. (2024) CC
Lancet 2024; 403: 533–44 R21/Matrix-M was well tolerated and offered high efficacy against clinical malaria in African children. This low-cost, high-efficacy vaccine is already licensed by several African countries, and recently received a WHO policy recommendation and prequalification, offerin... more
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Yobe, WHO and Malaria Consortium target close to 200,000 children for malaria prevention in high risk areas

World Health Organization WHO, Regional Office for Africa (2019) C_WHO
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Malaria - Children for Health

Children for Health (2025) C1
Older children play a crucial role in preventing malaria by encouraging the use of insecticide-treated bed nets and preventing mosquito breeding. They also support younger children during illness by assisting with nutrition and recovery activities. Recent advancements include the introduction of a m... more
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Caring for Newborns and Children in the Community. Facilitator Notes

World Health Organization; UNICEF (2011) C_WHO
Treat diarrhoea, confirmed malaria, and fast breathing
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Children and malaria: treating and protecting the most vulnerable

Medicines for Malaria Venture MMV (2019) C1
This document by Medicines for Malaria Venture (MMV) highlights the significant burden of malaria on children worldwide, emphasizing the need for effective prevention, diagnosis, and treatment strategies. It reviews current challenges and progress in combating pediatric malaria, advocating for conti... more
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Guidelines for the Diagnosis and Treatment of Malaria in Somalia

Federal Government of Somalia, Puntland & Somaliland, Zonal NMCPsMoH (2016) C1
The main objective of the malaria prevention and control programme in Somalia is to prevent mortality and reduce morbidity due to malaria. The groups most vulnerable to the disease, children aged under 5 years and pregnant women, are especially targeted. Effective case management - early diagnosis a... more
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Pre-referral treatment with rectal artesunate of children with suspected severe malaria: a field guide

World Health Organization WHO (2023) C_WHO
Prompt, effective antimalarial treatment, and supportive care can substantially reduce the rate of mortality from severe malaria. However, many children in malaria-endemic countries do not have access to health facilities or a qualified health care provider and do not receive the necessary care in a... more