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Tuberculosis (TB) remains a serious public health threat in South Africa and is the
leading cause of death in people living with HIV (PWH). Pre-hospital and early in-
hospital mortality is of particular concern in PWH. Significant progress has been made
to date, but a monumental effort is require
...
d to reach the END TB target of zero deaths
due to TB by 2035. One of the measures would be to curb early in-hospital mortality
due to TB. This goal provided impetus for the development of this package of care.
more
FORTBILDUNG – SCHWERPUNKT TUBERKULOSE HIV & More
Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV K-19 Tuberculosis/HIV Coinfection
Updated: September 12, 2024 Key Considerations and Recommendations
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
In: Antenatal Care, Maternal Care, Under 5 Clinics, Family Planning Clinics and HIV Exposed Child Follow Up.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretrovir
...
al therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written for medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
more
Bhana A et al. Journal of the International AIDS Society 2021, 24(S2):e25713
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes
organization of adolescent-friendly services to guide heath management teams and health
care workers (HCWs) on their roles. It also outlines important aspects to consider when
offering comprehensive care to adolescents an
...
d their parents/caregivers at health facilities
and in the community. Comprehensive care should include the provision of quality clinical
and psychosocial support (PSS) services with clear linkages to the community. These
services need to be adolescent-friendly at any health facility with clear prescription of
minimal standards, and has to be integrated into existing services at the health facility
more
A Training Manual for Community Service Providers
National Policy
Final Policy
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
more
The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
...
e outbreak, establishing a case definition, collecting epidemiological and laboratory data, identifying the source and mode of transmission, and implementing control measures. The guidelines also explain how to organize outbreak response teams, communicate findings, and document results in outbreak reports. Overall, the document aims to support systematic and effective outbreak investigations in order to control disease spread and protect public health.
more
PLoS ONE 18(12): e0295920. https://doi.org/10.1371/journal.pone.0295920. PLHIV were largely unaware and sceptical of U = U as the message appeared to contradict
the mainstream HIV prevention clinical guidance.
This guideline document is a publication of the National AIDS & STI Control Program, Ministry of Health
Kenya
Sustaining HIV Community-led Responses: Technical guidelines for costing and budgeting
UNAIDS
(2026)
Community-led responses (CLRs) are a vital pillar of the HIV response and central to achieving national and global targets, including the 30-80-60 commitments outlined in the 2021 Political Declaration on HIV and AIDS. These guidelines provide practical, step-by-step methods for costing and budgetin
...
g community-led responses (CLRs), tailored to the unique features of CLRs. They are designed for use by community-led organizations (CLOs), their partners, national governments, policy-makers, donors, and researchers involved in planning, implementing, financing or evaluating CLRs that address HIV.
more
Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
recommended
New
The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
...
s Guidelines outlines a structured approach to decentralization, focusing on:
Strategic Goals: Strengthening laboratory capacity at subnational levels to ensure timely detection and control of epidemic-prone diseases.
Guiding Principles: Equity, country ownership, multisectoral collaboration and evidence-based decision-making.
Implementation Framework: Practical steps for planning, executing, and sustaining decentralized diagnostic networks, with intra- and post-implementation reviews for continuous improvement.
Integration: Alignment with existing surveillance, case management and infection prevention and control (IPC) systems, with a focus on the One Health approach.
While the Guidelines is informed by the Mpox outbreak response, it is adaptable to other priority diseases and aligned with the International Health Regulations (IHR 2005), the Africa CDC Strategic Plan (2022-2027), and the WHO Health Security Framework.
more
Préparatiom et la riposte aux Épidémies er Afrique guide de Décentralisation des capacités de Laboratoire
recommended
New
L’augmentation en fréquence et en ampleur des urgences de santé publique en Afrique met en évidence
l’importance cruciale d’un dépistage précoce, d’une intervention rapide et d’un accès équitable aux
capacités de laboratoire. Les systèmes centralisés se sont souvent révélés
...
insuffisants, notamment
dans les zones reculées ou mal desservies, entraînant des retards dans la confirmation des cas et
réduisant l’efficacité des mesures de contrôle des épidémies.
La décentralisation des capacités de laboratoire constitue une stratégie transformative pour combler
ces lacunes. En rapprochant les examens diagnostiques des points de prestation de soins, les États
Membres de l’Union Africaine peuvent détecter les épidémies plus tôt, réagir plus efficacement et
renforcer la confiance du public dans les systèmes de santé.
Ce document propose un cadre global pour aider les États Membres à concevoir, mettre en œuvre
et pérenniser des réseaux de diagnostic décentralisés. Il met l’accent sur l’équité, l’appropriation
nationale, la collaboration multisectorielle et l’intégration avec les autres fonctions du système de santé.
De plus, il souligne l’importance du maintien des normes de qualité dans les contextes décentralisés,
en recommandant la mise en place de dispositifs de contrôle qualité adaptés, de mécanismes de
supervision ciblés et l’harmonisation avec les cadres nationaux d’assurance qualité.
Africa CDC, l’OMS et leurs partenaires restent déterminés à soutenir les États Membres à travers une
assistance technique, des plateformes de coordination et la mobilisation de ressources. Ensemble,
nous pouvons bâtir un écosystème de diagnostic résilient, réactif et inclusif, protégeant la santé de
toutes les communautés africaines.
more
Pediátrico Recomendaciones GRADE accessed August 2022
