This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is
a key component of leprosy treatment, as it is vital to prevent the progression of the infection.
Treatment with rifampin and other antibiotics is highly effective and cures 98% of patients with
the ...leprosy infection. Furthermore, the relapse rate is very low, at about 1% over 5–10 years.
There is little M. leprae drug resistance in leprosy and few reports of multi-drug resistance (1, 2, 3,
4, 5, 6, 7, 8). An antibiotic treatment may take months or years to produce clinical improvement,
especially in patients with an initial high bacterial index (BI).
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Antibiotics 2022, 11(3), 329; https://doi.org/10.3390/antibiotics11030329.
The authors found that the most-represented antibiotics on the Rwandan market were amoxicillin, co-trimoxazole and cloxacillin. No counterfeit antibiotics were found in this study. However, substandard batches with moderate ...deviations were found, suggesting that regular quality control of antibiotics is needed in Rwanda.
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(African Development Bank policy research document 1)
The report examines financing in the battle against malaria, focusing on the role of foreign aid. It analyzes whether or not a disease such as malaria can be controlled or eliminated in Africa without health aid. It also presents a theoretic...al model of the economics of malaria and shows how health aid can help avoid the “disease trap.” While calling for increased funding from international sources to fight malaria, it also recommends that African countries step up their own efforts, including on domestic resource mobilization. In 2016, governments of endemic countries contributed 31% of the estimated total of US $ 2.7 billion.
Between 2000 and 2014, malaria control efforts were scaled up and worldwide deaths were cut in half. But declining health aid and deprioritized vertical aid (as for malaria), despite its potentially great efficiency, have led to rising numbers of cases. In 2016, 216 million cases of malaria were reported, up from 211 million in 2015. Africa was home to 90% of all malaria cases and 91% of malaria deaths in 2016. Progress appears to have stalled in the global fight against the disease.
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While many of the countries hit by the COVID-19 in the first few months of the year are now beginning to relax lockdown measures as infection and death rates fall, in the regions most affected by HIV, TB and malaria, such as Africa, South Asia and Latin America, the pandemic continues to accelerate.... In lower resource settings, lockdowns are less effective and hard to sustain, and clinical care facilities are extremely limited. In such environments, the response to COVID-19 must focus on containing the pandemic’s spread as far as possible through testing, contact tracing and isolation, protecting the health workforce through training and the provision of personal protective equipment (PPE) and minimizing the knock-on impact on other diseases through shoring up fragile health systems, and adapting existing disease programs.
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Lancet Oncol 2022; 23: e251–312Published OnlineMay 9, 2022 https://doi.org/10.1016/S1470-2045(21)00720-8
In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality.
Without rapid interventions, data estimates show a major increase in cancer mo...rtality from 520 348 in 2020 to about
1 million deaths per year by 2030. Here, we detail the state of cancer in SSA, recommend key actions on the basis of
analysis, and highlight case studies and successful models that can be emulated, adapted, or improved across the
region to reduce the growing cancer crises. Recommended actions begin with the need to develop or update national
cancer control plans in each country. Plans must include childhood cancer plans, managing comorbidities such as
HIV and malnutrition, a reliable and predictable supply of medication, and the provision of psychosocial, supportive,
and palliative care. Plans should also engage traditional, complementary, and alternative medical practices employed
by more than 80% of SSA populations and pathways to reduce missed diagnoses and late referrals. More substantial
investment is needed in developing cancer registries and cancer diagnostics for core cancer tests.
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This regional report on the situation of tuberculosis (TB) in the Americas contains information from 2019, provided by the countries of the Region through the World Health Organization TB data collection system. These data have been consolidated and analyzed at the regional level. In addition to pre...senting the epidemiological and programmatic situation of TB in the Americas, the report aims to raise awareness and to motivate and encourage all stakeholders in the prevention and control of this disease, to accelerate efforts towards TB elimination in the Region, and to achieve the targets of the End TB Strategy. The report records the Region's achievements, but also the gaps in the work being carried out in diagnosis, treatment, comorbidities, vulnerable populations, risk factors, and funding, among other issues. Based on the information presented, specific recommendations are provided for further progress.
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Presently, there is no evidence that the virus responsible for the current COVID-19 pandemic is carried by domestic food-producing animals, such as chickens, ducks, other poultry, pigs, cattle, camels, horses, sheep, goats, rabbits, guinea pigs or fish. While live animals can be a source of pathogen...s, all types of food can potentially be contaminated through contact with contaminated equipment, surfaces or environments. Proper cleaning and the prevention of cross-contamination are critical in the control of foodborne illnesses. The application of sound principles of environmental sanitation, personal hygiene and established food safety practices will reduce the likelihood that harmful pathogens will threaten the safety of the food supply, regardless of whether the food is sourced from intensive agriculture, small stakeholders or wildlife.
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Bulletin of the World Health Organization 2016. doi: http://dx.doi.org/10.2471/BLT.16.171082
Objective: To describe the temporal and geographical distribution of Zika virus infection, and associated neurological disorders, from 1947 to February 2016.
Chapter 1 provides new data on the latest developments in the global treatment effort, highlighting positive trends as well as aspects that require improvement. Chapter 2 summarizes the impact of the scale-up in reducing AIDS-related mortality and new HIV infections. Chapter 3 examines the sequence ...of steps in the continuum of care from HIV diagnosis to successful provision of ART services and outlines key supportive innovations. Chapter 4 discusses the implications and anticipated impact of the new "Consolidated guidelines on the use of ARV drugs for treating and preventing HIV infection
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PEPFAR Malawi’s Country Operational Plan 2022 (COP22) embodies joint priorities from national and subnational dialogues building on the 2020-2025 National Strategic Plan for HIV/AIDS. The interagency team has developed a person-centered, district-tailored and Malawi Population-Based HIV Impact Ass...essment (MPHIA)-informed strategy through extensive engagement with Government of Malawi (GoM) and Civil Society Organizations (CSOs) to sustain HIV epidemic control. At the end of COP21, PEPFAR Malawi was commended for contributing to reaching epidemic control in strong collaboration with GoM and stakeholders including the Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund). This includes enrollment of 88% of recipients of care on three or more months of antiretroviral treatment (ART), better outcomes for Malawian children through remarkable efforts in Orphans and Vulnerable Children (OVC) programming and progress made towards reaching men with more intentional and focused programming.
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La méningite est mortelle et débilitante ; elle frappe brutalement ; elle a de graves conséquences sanitaires, économiques et sociales et touche tous les âges de la vie dans tous les pays du monde. La méningite bactérienne peut être à l’origine d’épidémies, entraîner la mort dans les... 24 heures et un patient sur cinq peut rester handicapé à vie à la suite d’une infection. La plupart des cas et des décès dus à la méningite pourraient être évités par la vaccination mais les progrès obtenus pour la vaincre sont bien moins rapides que ceux réalisés contre d’autres maladies à prévention vaccinale.
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Le présent document donne des lignes directrices provisoires afin de garantir l’efficacité des communications sur les risques relatives à la transmission du virus Zika et aux complications potentielles. Le lien de causalité entre l’infection à virus Zika et ces complications potentielles n...a pas encore été prouvé. Malgré ces incertitudes, des stratégies de communication efficaces devraient être mises en œuvre afin de permettre aux gens de prendre les meilleures décisions éclairées pour se protéger et protéger leurs familles et leurs communautés. Les présentes lignes directrices sont destinées à être utilisées par les responsables, le personnel et les bénévoles chargés de la communication sur les risques et la santé à l’échelle mondiale, régionale ou nationale; les professionnels de la communication; les anthropologues; les sociologues; les agents de santé; les administrateurs des hôpitaux; les responsables communautaires; les gestionnaires de programme et les décideurs politiques.
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The 2013 RMIS is a nationally representative, household-based survey that provides data on malaria indicators, which are used to assess the progress of a malaria control program. The primary objective of the 2013 Rwanda Malaria Indicator Survey (2013 RMIS) was to provide up-to date information on th...e prevention of malaria to policymakers, planners, and researchers.
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Globally, the cancer burden is rising, exerting significant strain on
populations and health systems at all levels of income. There are
concerted efforts towards enhancing access to comprehensive
cancer prevention and control initiatives.
Technical Update
Areas of Africa endemic for Buruli ulcer (BU), caused by Mycobacterium ulcerans, also have a high prevalence of human immunodeficiency virus (HIV), with adult prevalence rates between 1% and 5% (Maps). However, there is limited information on the prevalence of BU–HIV coinfection.... Preliminary
evidence suggests that HIV infection may increase the risk of BU disease (1–3). In the Médecins Sans Frontières project in Akonolinga, Cameroon, HIV prevalence was approximately 3–6 times higher among BU patients than the regional estimated HIV prevalence (2). Similarly in Benin and Ghana, BU
patients were 8 times and 3 times respectively more likely to have HIV infection than those without BU (1, 3). Further study is needed to clarify this association and enhance knowledge about the prevalence ofBU–HIV coinfection in endemic areas.
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Le Bénin est un pays à épidémie mixte car il existe des poches de concentration de fortes prévalences
au sein de certaines populations clés plus exposées aux risques d’infection, notamment les TS et
leurs partenaires, les prisonniers, les HSH et les UDI. Les sections suivantes présentero...nt la
prévalence dans les différents groupes.
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Le Bénin à l’instar des autres pays d’Afrique subsaharienne, fait face à une épidémie généralisée du VIH qui est actuellement au centre des préoccupations de santé publique et de développement. De 2002 à 2006, la prévalence nationale est stabilisée autour de 2% grâce à une améli...oration de la prise en charge des PVVIH, une augmentation du nombre de patients sous ARV, et un renforcement du partenariat avec la société civile y compris le secteur privé. En 2007, on a observé une légère inflexion à 1,7% de la prévalence.
Les conséquences multiples de l’infection par le VIH ont très vite imposé la nécessité d’une prise en charge globale des personnes infectées et affectées. Les interventions sont désormais multiples et intégrées allant de la prévention à la prise en charge en passant par le conseil - dépistage (CD).
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Le COVID-19 est un nouveau coronavirus, proche de celui du Syndrome Respiratoire Aigu Sévère (SRAS) qui avait été à l’origine d’une épidémie meurtrière en 2003. L’infection par ce nouveau coronavirus se manifeste le plus souvent par une fièvre et des signes respiratoires pouvant se co...mpliquer par un syndrome de détresse respiratoire aiguë. Jusqu’à présent, la plupart des cas graves ont été signalés chez des personnes souffrant d’autres problèmes de santé, comme le cancer, le diabète ou une maladie rénale ; ou encore parmi des travailleurs de la santé qui sont en contact étroit avec les malades.
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Note d’orientation | 16 March 2020
Ne pas causer de dommages, égalité, transparence et humanité - Les valeurs directrices pour guider la réponse de la justice pénale au Coronavirus
Au moment de la publication de cette note d’orientation, plus de 164’000 cas* de COVID-19, cette nouvell...e forme du coronavirus, avaient été enregistrés dans 100 pays, avec plus de 6’470 décès. Le présent document examine la situation en ce qui concerne les foyers d’infection au COVID-19 et les mesures de prévention dans les prisons**, ainsi que l’impact des réponses générales apportées par des gouvernements pour lutter contre la pandémie sur les personnes dans le système de justice pénale. Cette note d’orientation plaide pour une action immédiate au vu des risques auxquels sont exposés les personnes en milieu carcéral, y compris le personnel pénitentiaire.
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Orientations provisoires 16 décembre 2020
Le présent document résume les orientations de santé publique actuelles de l’OMS pour la surveillance de la maladie à coronavirus 2019 (COVID-19) chez l’homme due à une infection par le coronavirus 2 du syndrome respiratoire aigu sévère (SARS-Co...V-2) (ci-après désignée « surveillance de la COVID-19 »).
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