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Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Smith, E.E.; Saposnik, G.; Biessels. G.J. et al. American Heart Association (2016) CC
Two decades of epidemiological research shows that silent cerebrovascular disease is common and is associated with future risk for stroke and dementia. It is the most common incidental finding on brain scans. To summarize evidence on the diagnosis a ... more
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NLM Malaria Screener

National Library of Medicine (NLM) Lister Hill National Center for Biomedical Communications (2021) C2
The NLM Malaria Screener is a mobile app developed by the U.S. National Library of Medicine to support the diagnosis of malaria through automated analysis of blood smear images. It uses smartphone microscopy and machine learning to detect malaria pa ... more
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Integrated Management of Malaria Training - Health Workers Manual

The Ruepublic of Uganda - Ministry of Health (2019) C2
The "Integrated Management of Malaria Training – Health Worker’s Manual" is a practical guide developed by Uganda’s Ministry of Health to train healthcare workers at all levels in the effective diagnosis, treatment, prevention, and management ... more
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Leptospirosis – Fact Sheet - zoonotic disease with epidemic potential

Pan American Health Organization PAHO; World Health Organization World Health Organization WHO (2017) C_WHO
Leptospirosis is a zoonotic disease with epidemic potential, especially after a heavy rainfall, caused by a bacterium called Leptospira. Leptospira interrogans is pathogenic to humans and animals, with more than 200 serologic variants or serovars. Humans usually acquire leptospirosis through dire ... more
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Current challenges for confronting the public health problem of snakebite envenoming in Central America

Gutiéerrez, J. (2014) CC
Snakebite envenoming is a serious public health problem in Central America, where approximately 5,500 cases occur every year. Panama has the highest incidence and El Salvador the lowest. The majority, and most severe, cases are inflicted by the pit viper Bothrops asper (family Viperidae), locally kn ... more
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Waterborne Outbreaks of Hepatitis E: recognition, investigation and control

World Health Organization (WHO) (2014) C_WHO
Technical report
This manual aims to provide information about the methods for investigating outbreaks of hepatitis E, and measures for their prevention and control. In addition, the manual gives information about the causative agent – known as the hepatitis E virus (HEV) – its epidemiology ... more
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The natural history of chronic obstructive pulmonary disease

Mannino, D.M.; Watt, G.; Hole, D.; et al. European Respiratory Journal (ERJ) (2006) CC2
The article from the European Respiratory Journal discusses the natural history of chronic obstructive pulmonary disease (COPD), emphasizing its increasing global impact on morbidity and mortality. It highlights that while cigarette smoking is a primary risk factor, other influences such as environm ... more
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Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy

World Health Organization WHO (2017) C_WHO
The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all people living with HIV.
WHO recommends that a ... more
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2020 Heart Failure Society of South Africa perspective on the 2016 European Society of Cardiology Chronic Heart Failure Guidelines

Hitzeroth, J.; Mpe, M.; Klug, E. et al. The South African Medical Journal (2020) CC
Heart failure with a reduced ejection fraction (HFrEF) is a condition frequently encountered by healthcare professionals and, in order to achieve the best outcomes for patients, needs to be managed optimally. This guideline document is based on the European Society of Cardiology Guidelines for the t ... more
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Global breast cancer initiative implementation framework: assessing, strengthening and scaling up of services for the early detection and management of breast cancer: executive summary

World Health Organization WHO (2023) C_WHO
Breast cancer is the most common cancer worldwide and the leading cause of cancer deaths among women, disproportionately affecting low- and middle-income countries. The Global Breast Cancer Initiative strives to reduce breast cancer mortality by 2.5 percent per year, which over a 20-year period can ... more
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Guidelines for Diagnosing and Managing Disseminated Histoplasmosis among People Living with HIV
recommended

World Health Organization WHO (2020) C_WHO
Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum. This disease is highly endemic in some regions of North America, Central America, and South America and is also reported in certain countries of Asia and Africa. It often affects people with impaired immunity, including people ... more
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Integrated control of Chagas disease for its elimination as public health problem - A Review

Sosa-Estani, S.; Segura, E.L. Memórias do Instituto Oswaldo Cruz (2015) C2
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America. Chagas disease, as determined by the factors and determinants, shows that different contexts require different actions, ... more
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Human African trypanosomiasis. Seminar

Büscher P., Cecchi G., Jamonneau V. et al (2017) C2
The Lancet Volume 390, Issue 10110p2397-2409November 25, 2017. Human African trypanosomiasis (HAT), also called sleeping sickness, is a parasitic infection that almost invariably progresses to death, unless treatment is provided. HAT caused devastating epidemics during the 20th century. Thanks to ... more
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Diagnostic methods for the control of strongyloidiasis, Virtual meeting, 29 September 2020

World Health Organization WHO (2021) C_WHO
23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the ... more
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Neurology in Africa
recommended

William Howlett (2012) C1
The whole book has 50.3 MB!!!! To download chapter by chapter: http://www.uib.no/cih/en/resources/neurology-in-africa Africa is a vast continent and neurological disorders are a common cause of disability and death. This practical neurology textbook is specifically written for Sub-Saharan Africa. ... more
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Mycetoma: Training of health workers at national and district levels on skin-NTDs

Open WHO; World Health Organization WHO (2021) C_WHO
Mycetoma is a chronic, progressively destructive infectious disease of the subcutaneous tissues, affecting skin, muscle and bone. Mycetoma occurs in tropical and subtropical environments characterized by short rainy seasons and prolonged dry seasons that favour the growth of thorny bushes. Global bu ... more
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.

Bernhard, S.; Kaiser, M.; Burri, C.; Mäser, P. Diseases (2022) CC
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-cli ... more
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Diagnosis Prevention and Management of Cryptococcal Disease in HIV-infected Adults and Children

WHO (2011)
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Diagnosis and treatment of Ebola and Marburg virus disease

M. Bray, M.S.Hirsch, D.Mitty (2014)
The publisher agreed to open UptoDate and the full content of the Ebola section is now freely available here
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Background document: the diagnosis, treatment, and prevention of typhoid fever

World Health Organization (2003) C_WHO