Heart failure with a reduced ejection fraction (HFrEF) is a condition frequently encountered by healthcare professionals and, in order to achieve the best outcomes for patients, needs to be managed optimally. This guideline document is based on the European Society of Cardiology Guidelines for the t...reatment of acute and chronic heart failure published in 2016, and summarises what is considered the best current management of patients with the condition. It provides information on the definition, diagnosis and epidemiology of HFrEF in the African context. The best evidence-based treatments for HFrEF are discussed, including established therapies (beta-blockers, ACE-i/ARBs, mineralocorticoid receptor antagonists (MRAs), diuretics) that form the cornerstone of heart failure management as well as therapies that have only recently entered clinical use (angiotensin receptor-neprilysin inhibitor (ARNI), sodium/glucose cotransporter-2 (SGLT2) inhibitors). Guidance is offered in terms of more invasive therapies (revascularisation, implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy (CRT) by implantation of a biventricular pacemaker with (CRT-D) or without (CRT-P) an ICD, left ventricular assist device (LVAD) use and heart transplantation) in order to ensure efficient use of these expensive treatment modalities in a resourcelimited environment. Furthermore, additional therapies (digoxin, hydralazine and nitrates, ivabradine, iron supplementation) are discussed and advice is provided on general preventive strategies (vaccinations). Sections to discuss conditions that are particularly prevalent in sub-Saharan Africa (HIV-associated cardiomyopathy (CMO), peripartum CMO, rheumatic heart disease, atrial fibrillation) have been added to further improve clinical care for these commonly encountered disease processes.
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Time has seen management for Cystic Fibrosis (CF) advance drastically, most recently in the development of the disease-modifying triple combination therapy ivacaftor/tezacaftor/elexacaftor. There is currently limited evidence regarding both the global epidemiology of CF and access to this transforma...tive therapy - and therefore where needs are not being met. Therefore, this study aims to define gaps in access to CF treatment. The results show that a significant CF patient burden exists in countries where disease-modifying drugs are unavailable, and final figures are likely underestimates. This analysis shows the potential to improve rates of diagnosis and treatment for CF, so a higher percentage of patients receive the most effective triple combination treatment.
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Diabetes is a major public health problem. The rising incidence of Diabetes Type 2 is related to the effects of urbanization and unhealthy lifestyles. Research studies show that healthy eating and regular physical activity can prevent or delay the onset of Diabetes Type 2, even in high-risk individu...als.
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Work can be beneficial or harmful to mental health depending on
the circumstances. If a person has a mental health problem, being
at work in a supportive workplace can assist in their recovery. The
level of support needed will fluctuate, as the symptoms of most
mental health problems come and go... over time.
Providing mental health first aid when a worker is showing the
early signs and symptoms of a mental health problem is important,
as it can assist the person to return to their usual performance
quickly. Failing to provide mental health first
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HRH SA 2030 | Draft HR Strategy for the Health Sector: 2012/13 – 2016/17 Consultation Document
In Paraguay, 1.8% of the population are indigenous people. The Maká community
29 mainly live in urbanized areas in the Central Region. This study focuses on the epidemiology
30 of tuberculosis (TB) among indigenous Maká and the non-indigenous people living in the
31 Central Region, the biggest ...metropolitan area of the Paraguay.
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Во Всемирном докладе о наркотиках содержится комплексная информация по положению в области незаконных наркотиков. В нем представлены подробные оценки и тенденци..., относящиеся к производству, незаконному обороту и потреблению на рынках опиума/героина, коки/кокаина, каннабиса и стимуляторов амфетаминового ряда. Масштабы проблемы наркотиков удается ограничивать, но существуют признаки того, что стабилизация, достигнутая за последние несколько лет, может подвергаться риску. Среди этих признаков – расширение культивирования в 2007 году опийного мака и коки, некоторый прирост потребления в развивающихся странах и в определенной степени развитие новых схем незаконного оборота. Также отмечалось обнадеживающее сокращение некоторых из основных потребительских рынков.
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These guidelines provide a framework for effective action to facilitate access to safe and ethical
testing services for different population groups. The implementation of the a comprehensive
approach, known as HIV Testing Services (HTS) is cardinal as an effective package of services
that diminis...hes the impact of the HIV epidemic in our country. All forms of HTS adhere to
the 5Cs: Confidentiality, Counselling, Consent, Correct results and Connection, or linkage
to care, with all based within a human right context. In addition to the 5Cs, however, the
MOHCDGEC emphasizes the use of a variety of approaches to HTS that will reduce the
number of missed opportunities. These include Provider-Initiated Testing and Counselling
testing, Couple counselling and testing, Index testing, and infant and children counselling and
testing in alignment to the revised WHO guidelines. Furthermore, these guidelines accentuate
on the continual provision of integrated HTS service at all levels of the public and private
health service delivery system.
The HTS Providers, managers and other stakeholders
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Свод методических рекомендаций по вопросам политики и оказания услуг в области психического здоровья. На долю психических расстройств приходится значительная ча...сть бремени болезней во все странах. Несмотря на то, что уже имеются действенные виды вмешательств, они недоступны для большинства людей, нуждающихся в них. Обеспечить их полноценную доступность
можно путем внесения изменений в политику и законодательство, через создание новых
служб, обеспечение адекватного финансирования и проведение подготовки соответствующих кадров.
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World Drug Report 2018
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A workshop methodology for children, young people and adults
The “Tree of Life” is a psychosocial support tool based on narrative practices that is designed to help participants accept the hardships of their past and identify the strengths that can help them achieve a better future. It uses th...e different parts of a tree as metaphors to represent the different parts of our lives. The workshop generally takes one day.
Participants draw their own “Tree of Life” in which they get to speak of their ‘roots” (where they come from), their skills and knowledge, their hopes and dreams and the special people in their lives
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This South-East Asia Regional Strategy for Primary Health Care: 2022-2030 aims to accelerate progress in all countries of the Region towards universal health coverage (UHC), health security and the health-related Sustainable Development Goals (SDGs). It is intended to provide Member States with guid...ance on facilitating PHC-orientation through the identification of seven values and 12 strategic actions that collectively embody the philosophy and practice of PHC, enunciated in the 1978 Declaration of Alma-Ata and reaffirmed in the 2018 Declaration of Astana.
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DHS Analytical Studies No. 36