To generate and manage resources towards this goal, the UN Secretary-General in collaboration with UN Agencies, Funds and Programmes (UN AFP) has launched the UN Zika Response Multi-Partner Trust Fund (Zika Response MPTF). The aim of this inter-agency pooled funding mechanism is to rapidly resource ...the UN system responses to Zika virus, in accordance with the overview of needs and requirements and the Zika Response Framework.
more
Documento de trabajo
Considerando, las Alertas Epidemiológicas sobre el nuevo coronavirus (COVID-19) publicadas en enero y la más reciente 5 de febrero del 2020 (disponibles en: https://www.paho.org/hq/index.php?option=com_docman&view=download&category_slug=coronavir us-alertas-epidemiologicas&...alias=51567-5-de-febrero-de-2020-nuevo-coronavirus-ncov-actualizacionepidemiologica-1&Itemid=270&lang=es que refieren la circulación de este virus en al menos 23 países, según lo reportado a la Organización Mundial de la Salud (OMS).
Así mismo, que a esta fecha, continua la incertidumbre sobre el nuevo patógeno y el espectro de manifestaciones que pueda causar, la fuente de infección, el modo de transmisión, el periodo de incubación, la gravedad de la enfermedad y las medidas específicas de control: y que, existe un riesgo teórico de transmisión del virus a través de la transfusión de productos sanguíneos lábiles como: sangre completa, preparaciones de glóbulos rojos, preparaciones de plaquetas, preparaciones de granulocitos, plasma fresco congelado y crioprecipitado.
more
14 July 2021 This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series.
COVID-19 vaccines have proven to be safe, ...effective and life-saving. Like all vaccines, they do not fully protect everyone who is vaccinated, and we do not yet know how well they can prevent people from transmitting the virus to others. So as well as getting vaccinated, we must also continue with other measures to fight the pandemic.
Available in English, French, Spanish, Arabic, Chinese and Russian
more
Immunizations are an essential health service that protect susceptible individuals from vaccine-preventable diseases (VPD).2 By providing timely immunizations, individuals and communities remain protected and the likelihood of a VPD outbreak decreases, Preventing a VPD ...outbreak not only saves lives but requires fewer resources than responding to the outbreak and helps reduce burden on a health system already strained by the COVID-19 pandemic, While committing to sustaining immunization systems, countries should use approaches that respect the principle of do-no-harm and limit transmission of COVID-19 while providing immunization activities, Immunization visits can also be used as opportunities to disseminate messages to encourage behaviours to reduce transmission risk of the COVID-19 virus, to identify signs and symptoms of COVID-19 disease, and to provide guidance on what to do if symptoms emerge
more
Os sistemas de saúde estão enfrentando um rápido aumento na demanda gerada pelo surto da COVID-19. Quando os sistemas de saúde ficam sobrecarregados, há um aumento drástico na mortalidade direta causada por um surto e também na mortalidade indireta por doenças imunopreveníveis e por aquelas... doenças que possuem tratamento. Análises do surto de ebola em 2014-2015 sugerem que o aumento no número de óbitos causados por sarampo, malária, HIV/AIDS e tuberculose atribuíveis a falhas no sistema de saúde ultrapassou o número de óbitos causados pelo ebola. A capacidade de um sistema de manter a prestação de serviços essenciais de saúde dependerá de sua capacidade inicial e da carga da doença e do contexto de transmissão do vírus COVID-19 (classificado como nenhum caso, transmissão esporádica, em clusters ou comunitária). Manter a confiança da população na capacidade do sistema de saúde de atender, com segurança, as necessidades essenciais e de controlar o risco de infecção nas unidades de saúde é fundamental para garantir que as pessoas continuem a buscar atendimento quando necessário e que sigam as orientações de saúde pública.
more
The growing understanding of how sequence information can contribute to improved public health is driving global investments in sequencing facilities and programmes. The falling cost and complexity of generating GSD provides opportunities for expanding sequencing capacity; however, challenges to wid...espread implementation remain. This document provides policy-makers and stakeholders with guidance on how to maximize the public health benefit of SARS-CoV-2 genomic sequencing activities in the short and long term as the pandemic continues to unfold. Practical considerations for the implementation of a virus genomic sequencing programme and an overview of the public health objectives of genomic sequencing are covered. This guidance focuses on SARS-CoV-2 but is applicable to other pathogens of public health concern.
more
The World Health Organization (WHO) projects a global shortfall of 18 million health workers by 2030, mostly in low- and lower-middle-income countries. Contributing to the global deficit are chronic under-investment in education and training of health workers; workforce migration; an aging health wo...rkforce; rapid increases in chronic diseases; and inability to track existing human resources using health information systems. Health care worker shortages are compounded by the increased portability and virulence of infections. Rapid population growth, climate change, deforestation, international travel, migration, poverty, and social inequality have dramatically increased the risk of pandemics and highlighted the need for skilled health workforce to effectively respond to emerging health threats. This is evident now more than ever as COVID-19 exacerbates health inequity and barriers to access, and further strains the already fragile health systems in many countries.
more
Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
more
A major objective of this open access book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatmen...t of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans. ; Supports further investigation by summarizing state of the art in the field of Buruli ulcer research Enriches understanding of epidemiology of Buruli ulcer in different geographic regions Reviews exhaustively the characteristics of Mycobacterium ulcerans disease
more
n light of the potential risk posed by SARS-CoV-2 variants, in January 2021 WHO organized an ad hoc consultation to discuss the development of an R&D agenda in response to existing and emerging SARS-CoV-2 variants.
The key objectives were to identify the critical research questions related to var...iants and agree on a research approach to address them. Six breakout groups covered a range of specific issues related to COVID-19 variants: Epidemiology and mathematical modelling; evolutionary biology; animal models; assays and diagnostics; clinical management and therapeutics; and vaccines.
This report is a summary of presentations and panel discussions.
more
What do we know about Omicron variant so far? WHO's Dr Maria Van Kerkhove updates on the transmissibility, severity, symptoms and ways to protect yourself in Science in 5.
If Omicron is less severe, why are people ending up in the hospital and dying from it? Is it true that everyone will eventually get Omicron? Why is it important to reduce transmission? WHO's Dr Maria Van Kerkhove explains in Science in 5.
Interim guidance, 12 August 2020This interim guidance has been updated with advice on safe and appropriate home care for patients with coronavirus disease 2019 (COVID-19) and on the public health measures related to the management of their contacts.
Updated 24 March 2020 (24 Maart 2020)
BMJ 2020;368:m800 doi: 10.1136/bmj.m800 (Published 5 March 2020)
Outline
• Welcome and objectives
• Microbiology, epidemiology and clinical presentation
• Surveillance for imported cases including case definitions
• Laboratory diagnosis • Infection prevention and hospital readiness
• Patient flow and actions required at each step
• Co-ord...inating a public health response
more
Accessed: 31.03.2020
French:
ÉTATS MEMBRES DE L’UNION AFRICAINE NUMÉROS D’URGENCE DE LA COVID-19 (HOTLINES) - Centres africains de prévention et de contrôle des maladies
Arabic:
أرقام الطوارئ المخصصة للكوفيد-١٩ في الدول... الأعضاء في) الاتحاد الأفريقي (الخطوط الساخنة)
more
Временные рекомендации
13 марта 2020 г.
Настоящий документ является вторым изданием руководства (версия 1.2), которое первоначально представляло собой адаптированн...ый вариант Руководства по клиническому ведению тяжелой острой респираторной инфекции при подозрении на инфекцию MERS-CoV (ВОЗ, 2019 г.).
more