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6
Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure rate (CR) and intensity reduction rate (IRR). Here,
...
we determined the efficacy of a single versus four repeated treatments with PZQ on Schistosoma mansoni infection in school-aged children from Côte d'Ivoire, using two different diagnostic tests.
more
Antimicrobial resistance (AMR) is a global human, animal, plant and environment health threat that needs to be addressed by every country. The impacts of AMR are wide-ranging in terms of human health, animal health, food security and safety, environmental effects on ecosystems and biodiversity, and
...
socioeconomic development. Just like the climate crisis, AMR poses a significant threat to the delivery of the 2030 Agenda for Sustainable Development. The response to the AMR crisis has been spearheaded through the global action plan on antimicrobial resistance (GAP-AMR), developed by the World Health Organization (WHO) in 2015, in close collaboration with the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (WOAH), and formally endorsed by the three organizations’ governing bodies and by the Political Declaration of the high-level meeting of the United Nations General Assembly on AMR in 2016. In 2022, the three organizations officially became the Quadripartite by welcoming the United Nations Environment Programme (UNEP) into the alliance “to accelerate coordination strategy on human, animal and ecosystem health”.
The aim of the GAP-AMR is to ensure the continuity of successful treatment with effective and safe medicines.
Its strategic objectives include:
• improving the awareness and understanding of AMR;
• strengthening the knowledge and evidence base through surveillance and research;
• reducing the incidence of infection through effective sanitation, hygiene and infection prevention measures; optimizing the use of antimicrobial medicines in human and animal health; and
• developing the economic case for sustainable investment that takes account of the needs of all countries and increasing investment in new medicines, diagnostic tools, vaccines and other interventions.
With the adoption of the GAP-AMR, countries agreed to develop national action plans (NAPs) aligned with the GAP-AMR to mainstream AMR interventions nationally. Individually, the Quadripartite took action to advance AMR interventions in their respective sectors. FAO adopted a resolution on AMR recognizing that it poses an increasingly serious threat to public health and sustainable food production, and developed an AMR action plan to support the resolution’s implementation. For its part, WOAH developed a strategy on AMR aligned with the GAP-AMR, acknowledging the importance of a One Health approach to AMR. Similarly, more recently, UNEP’s governing body, the United Nations Environment Assembly, recognized that AMR is a current and increasing threat and a challenge to global health, food security and the sustainable development of all countries, and welcomed the GAP-AMR and the NAPs developed in accordance with its five overarching strategic objectives
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Epidemics and pandemics of infectious diseases are occurring more often, and spreading faster and further than ever, in many different regions of the world. The background factors of this threat are biological, environmental and lifestyle changes, among others. A potentially fatal combination of new
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ly-discovered diseases, and the re-emergence of many long-established ones, demands urgent responses in all countries. Planning and preparation for epidemic prevention and control are essential. The purpose of the Managing epidemics handbook is to provide expert guidance on those responses. Building on the first edition, the second edition provides concise and basic up-to-date knowledge with which public health officials can respond effectively and rapidly at the very start of an outbreak. Part I of the handbook provides insights on epidemics of the 21st century and offers context on the upsurge of recent epidemics. Part II has been updated and offers 10 key facts about 19 deadly diseases including tips on the interventions required to respond. Part III presents various Tool boxes that summarize guidance on several important topics. The handbook focuses on practical and indispensable things to know about infectious diseases that are most important for national, political and operational decision-makers; it also links readers to more exhaustive WHO guidan
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2021 World Health Organization guideline on pharmacological treatment of hypertension: Policy implications for the region of the Americas
Campbell, N.R.C.; Burnens, M.P.; Whelton, P.K. et al.
The Lancet Regional Health - Americas
(2022)
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Cardiovascular disease (CVD) is the leading cause of death in the Americas and raised blood pressure accounts for over 50% of CVD. In the Americas over a quarter of adult women and four in ten adult men have hypertension and the diagnosis, treatment and control are suboptimal. In 2021, the World Hea
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lth Organization (WHO) released an updated guideline for the pharmacological treatment of hypertension in adults. This policy paper highlights the facilitating role of the WHO Global HEARTS initiative and the HEARTS in the Americas initiative to catalyze the implementation of this guideline, provides specific policy advice for implementation, and emphasizes that an overarching strategic approach for hypertension control is needed. The authors urge health advocates and policymakers to prioritize the prevention and control of hypertension to improve the health and wellbeing of their populations and to reduce CVD health disparities within and between populations of the Americas.
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Factors to take into account when choosing, reviewing and changing medicines.
Rescue therapy:
For symptomatic hyperglycaemia, consider insulin or a sulfonylurea and review when blood glucose control has been achieved.
Diet and lifestyle advice:
At each point reinforce advice about diet and life
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style.
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The article on the PAHO website discusses the health risks of excessive salt consumption, which contributes to numerous deaths worldwide. It highlights that average salt intake significantly exceeds WHO recommendations, particularly in the Americas, and suggests measures like reducing salt in foods
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and implementing clear nutritional labeling to prevent diseases.
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This leaflet is intended to inform physicians — mainly GPs — and medical students on how to recognize a possible radiation injury. It is important to note that radiation injury has no special signs and symptoms. However, the combination of some of them may be typical of radiation injury.
Arabic
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version available: http://www.who.int/ionizing_radiation/pub_meet/en/Arabicleaflet.pdf?ua=1
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Initial clinical management of patients exposed to clinical weapons: Emergency wet decontamination using the 'rinse-wipe-rinse' technique is simple, effective and requires minimal equipment and training. This technique may be adapted to the situation and available resources.
Also available in Arab
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ic: http://www.who.int/environmental_health_emergencies/deliberate_events/decontamination_steps_ar.pdf?ua=1
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Le présent manuel a pour objet d'orienter les États membres sur les aspects pratiques du maintien des normes sanitaires aux frontières internationales dans les ports, les aéroports et les passages à niveau (points d'entrée) énoncés dans le Règlement sanitaire international (2005). Il fourni
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t des conseils techniques pour l'élaboration d'un programme complet de surveillance systématique des vecteurs de maladies et de lutte intégrée contre les vecteurs aux points d'entrée.
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Orientierungsrahmen für die psychische Gesundheit und psychosoziale Unterstützung (MHPSS) in der Entwicklungszusammenarbeit
Sigmund Freud Privatuniversität; BAff; Charité; et al.
Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH
(2018)
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Am Beispiel des Kontexts der Syrien- und Irakkrise
Das Positionspapier zeigt auf, was gute psychosoziale Arbeit mit Geflüchteten ausmacht und welche Risiken es zu berücksichtigen gilt. Es richtet sich an Akteur*innen aus dem MHPSS-Sektor, die im Kontext der Syrien- und Irakkrisen mit Flüchtlinge
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n im Nahen Osten arbeiten sowie an Ministerien und wissenschaftliche Institutionen.
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This timely report comes at a decisive moment in history where
we can reshape urban environments and health systems for the
majority of the world’s population that live in cities. Enabling
this transformation are the SDGs, which have reconfigured how
governments and the international community
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need to plan and
implement actions to eradicate poverty and inequality, create
inclusive economic growth, preserve the planet and improve
population health. Central to this quest is to create equitable,
healthier cities for sustainable development.
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