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Tuberculosis (TB) remains a serious public health threat in South Africa and is the leading cause of death in people living with HIV (PWH). Pre-hospital and early in- hospital mortality is of particular concern in PWH. Significant progress has been made to date, but a monumental effort is require ... more
This issue brief provides information about TB and HIV clinical trials and research programs impacted by U.S. government funding disruptions, and proposes urgent actions that donor agencies, governments, and philanthropies can take to preserve scientific advances underway and prevent the collapse ... more
July 2023 version .The 2023 ART guideline introduces simplified ART provision and harmonised methods of management of children, adolescents and adults, as well as pregnant women living with HIV/AIDS, TB and other common opportunistic infections. The guidelines also provide guidance on the use of D ... more
This booklet is aimed at HCP’s, and serves to raise awareness, and emphasize the need for the inclusion and integration of psychosocial support in the Comprehensive HIV and AIDS Care, Management and Treatment (CCMT) of children and adolescents.
A Clinical Guideline for the Diagnosis and Treatment of Drug-susceptible TB in Children and Adolescents in South Africa. This new guidance is aligned with the updated WHO guidelines but has been adapted specifically for the South African context. The intention of this publication is to provide g ... more
Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un ... more
What is new in this guideline. Fact Sheet
Annexure 6 National Guidelines South Africa 2023

A Flipchart for Child an Adolescent Disclosure Counseling (CADC) SOP3

Levin, L.; M. Vujovic, and J. Turner Ministry of Health, South Africa; PEPFAR; USAID; Right to Care; et al. (2024) C1
Right to Care mini flipster
National Policy
SOP number SOP000108/2020
These guidelines focus on the provision of PrEP as part of comprehensive combination prevention, drawing on implementation and research evidence and WHO recommendations.
Annex A
April 2025 – MARCH 2026
39th African Union (AU) Summit, Addis Ababa, Ethiopia, February 2026
Journal of the International AIDS Society 2024, 27:e26233. Most adult ART clients in South Africa were satisfied with their care, but those enrolled in DSD models expressed slightly greater satisfaction than those remaining in conventional care. Efforts should focus on enrolling more eligible patie ... more
Southern African HIV Clinicians Society (SAHCS) Clinical Update, May 2022
There has been major progress in the HIV response in eastern and southern Africa, the region most affected by the HIV pandemic.
Southern African Journal of HIV Medicine
medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC commitments in the largest HIV epidemic in the world leads to increased incidence and mortality and threatens decades of progress in KZN, South Africa. Rest ... more