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Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Weekly epidemiological record.
This report presents progress made in 2023–2024 towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021–2030 (the road map), including several important analytical updates
July 2023 version .The 2023 ART guideline introduces simplified ART provision and harmonised methods of management of children, adolescents and adults, as well as pregnant women living with HIV/AIDS, TB and other common opportunistic infections.
The guidelines also provide guidance on the use of D
...
olutegravir (DTG) dispersible tablets for children from 3kg and 4 weeks old.
These guidelines have been revised with the Differentiated Models of Care SOPs to ensure simultaneous consideration and alignment of clinical, adherence and service delivery updates.
more
A toolkit for health facilities. This toolkit highlights successful differentiated-care approaches implemented in a number of settings and countries in sub-Saharan Africa. The toolkit will be further updated as more experience is gained with these and similar
approaches
This is the 2025 draft Malawi Guidelines for Syndromic Management of Sexually Transmitted Infections which is yet to be approved by the SMT.
This 5th Edition of the Malawi Guidelines for Clinical Management of HIV in Children and Adults is implemented from January 2022. It replaces all previous editions of the Malawi Antiretroviral therapy (ART) and Prevention of Mother to Child Transmission (PMTCT) guidelines.This document is written fo
...
r medical doctors, clinical officers, medical assistants, nurses, midwives, laboratorians, health surveillance assistants (HSAs) and medical records clerks who are working in public and private sector health facilities in Malawi. It is designed to be a practical guide for implementation of integrated HIV Services
more
Essential triple EMTCT services include testing for HIV, syphilis and HBV in ante-
natal care (ANC) settings; prompt and efficacious interventions to treat women
who test positive; prevent transmission of any of the infections to their children;
counseling for women and their partners to reduce t
...
ransmission risk and ensure
appropriate treatment; encourage clean and safe delivery; appropriate follow
up of exposed infants including provision of HBV vaccine birth dose; promoting
optimal infant-feeding; and lifelong treatment and care for mothers living with
HIV or those eligible for treatment for hepatitis B infections and treatment for
syphilis.
more
Technical Document
Bhana A et al. Journal of the International AIDS Society 2021, 24(S2):e25713
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes
organization of adolescent-friendly services to guide heath management teams and health
care workers (HCWs) on their roles. It also outlines important aspects to consider when
offering comprehensive care to adolescents an
...
d their parents/caregivers at health facilities
and in the community. Comprehensive care should include the provision of quality clinical
and psychosocial support (PSS) services with clear linkages to the community. These
services need to be adolescent-friendly at any health facility with clear prescription of
minimal standards, and has to be integrated into existing services at the health facility
more
This comprehensive analysis outlines the recommended mental health services in HIV
care, delivery modalities, required resources, guideline integration, special population
considerations, and implementation strategies with real-world examples
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health
Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for
HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact
...
urers long-term arrangements
(LTAs) to supply WHO prequalified product
more
A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14) in Orphans and Vulnerable Children (OVC) Programs
Ces orientations opérationelles ont pour but de soutenir les pays dans le processus d’introduction d’un antibiotique. Leur objectif est de garantir un accès rapide aux antimicrobiens et l’utilisation appropriée de ces produits ainsi que des résultats optimaux pour les patients, tout en ré
...
duisant le risque de résistance émergente, en offrant des conseils sur la manière d’introduire un antibiotique dans les systèmes de santé nationaux. Elles se concentrent principalement sur les antibiotiques relevant des groupes de classification « Watch » (utilisation sélective) et « Reserve » (dernier recours), qui sont généralement utilisés comme traitements de deuxième et troisième intention en milieu hospitalier. Ceux-ci sont essentiels pour traiter les organismes multirésistants mais sont souvent confrontés à des difficultés spécifiques en matière d’accès, en particulier dans les pays à revenu faible ou intermédiaire. Les présentes orientations décrivent une approche de planification pour l’introduction et la mise en oeuvre de ces produits, en tenant compte de leurs caractéristiques uniques et des besoins connexes, dans le but d’améliorer l’accès au traitement pour les patients et de promouvoir globalement l’utilisation appropriée des antibiotiques.
more
medRxiv- The preprint server for health sciences
recommended
Preprints are preliminary reports of work that have not been certified by peer review. They should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv
Researchers are devising a clinical-trial protocol to test three medicines in Africa's latest outbreak
Nature doi: 10.1038/d41586-018-06132-7
NICE Scientific Advice is providing free fast track advice for researchers who are developing novel diagnostics or therapeutics for COVID-19. The team is working to help researchers from around the world optimise their approach to generating the essential evidence required for health technology ass
...
essments, which inform decision making.
more