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This edition provides detailed guidance on essential components such as infrastructure, human resources, equipment, logistics, governance, and monitoring and evaluation (M&E). These elements are crucial for the successful establishment and sustainable operation of NPHIs, which are envisioned as Cent
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res of Excellence for public health in Africa.
more
This document suggests mechanisms that countries can use to respond to emergencies and disasters taking a whole of society and whole of government approach ensuring multisectoral engagement for health actions. It helps to run a participatory process of developing the national health response operati
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ons plan that brings together all relevant sectors, public health experts, civil society and the international community under government leadership and facilitate ownership, adoption, testing through simulation and finally successful implementation in responding to emergencies and disasters from multiple hazards.
more
Hand hygiene is a simple yet powerful tool in interrupting the transmission of the monkeypox virus (MPXV) and other infectious disease both in healthcare facilities and communities. However millions still lack access to basic hygiene services particularly in vulnerable and resource limited settings.
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Governments must urgently ensure universal access to functioning hand hygiene stations in public and healthcare facilities, promote correct hand hygiene practices, and integrate hand hygiene into national polices and response strategies, to contain mpox. There is a need for multimodal approach- combining political leadership, availability of supplies, evidence based behavioral change strategies and strengthened healthcare practices is critical.
more
The ultimate aim of the framework is to assist the user to thoughtfully, deliberately, ethically, and rationally determine whether or not the delivery of one or more vaccines to specific target populations during the acute phase of an emergency would result in an overall saving of lives, a reduction
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in the population burden of disease, and generally more favourable outcomes than would otherwise be the case.
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Key resources include the Manual for Disaster Response Teams, which helps experts plan public communication, exchange information, and manage media, ensuring crucial data reaches humanitarian actors
Lessons learned around RCCE in outbreak responses in East and Southern Africa recognise the need to learn from and strengthen national and cross-border collaboration in the face of frequent public health emergencies. In October 2023, One Health partners conducted a Simulation Exercise in the Mandera
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region between Ethiopia, Kenya, and Somalia to test cross-border readiness. One of the key recommendations from this workshop was that current and future agreements, plans, and SOPs on One Health Emergency Preparedness and Response (EPR) in all three countries should include RCCE for cross-border situations.
more
This toolkit lays out a framework for a waterborne disease investigation and consolidates resources to assist investigation activities.
The Waterborne Disease Outbreak Investigation Toolkit was designed to assist state and local health departments in conducting waterborne disease outbreak invest
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igations. Using experiences of epidemiologists at the state and local levels, this toolkit describes best practices in preparing for, identifying, and responding to a waterborne disease outbreak.
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The manual elaborates on a wide rang of logistics management issues such as carrying assessements, procurement, storing, transporting and distribution of emergency supplies
Sustaining HIV Community-led Responses: Technical guidelines for costing and budgeting
UNAIDS
(2026)
Community-led responses (CLRs) are a vital pillar of the HIV response and central to achieving national and global targets, including the 30-80-60 commitments outlined in the 2021 Political Declaration on HIV and AIDS. These guidelines provide practical, step-by-step methods for costing and budgetin
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g community-led responses (CLRs), tailored to the unique features of CLRs. They are designed for use by community-led organizations (CLOs), their partners, national governments, policy-makers, donors, and researchers involved in planning, implementing, financing or evaluating CLRs that address HIV.
more
Epidemic Preparedness and Response in Africa | Guidelines for the Decentralization of Laboratory Capacity
recommended
The decentralization of laboratory capacities is a critical strategy for improving epidemic preparedness and response in Africa. Centralized systems often delay case confirmation, hinder timely interventions, and exacerbate the impact of outbreaks, especially in rural and hard-to-reach areas.
Thi
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s Guidelines outlines a structured approach to decentralization, focusing on:
Strategic Goals: Strengthening laboratory capacity at subnational levels to ensure timely detection and control of epidemic-prone diseases.
Guiding Principles: Equity, country ownership, multisectoral collaboration and evidence-based decision-making.
Implementation Framework: Practical steps for planning, executing, and sustaining decentralized diagnostic networks, with intra- and post-implementation reviews for continuous improvement.
Integration: Alignment with existing surveillance, case management and infection prevention and control (IPC) systems, with a focus on the One Health approach.
While the Guidelines is informed by the Mpox outbreak response, it is adaptable to other priority diseases and aligned with the International Health Regulations (IHR 2005), the Africa CDC Strategic Plan (2022-2027), and the WHO Health Security Framework.
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Préparatiom et la riposte aux Épidémies er Afrique guide de Décentralisation des capacités de Laboratoire
recommended
L’augmentation en fréquence et en ampleur des urgences de santé publique en Afrique met en évidence
l’importance cruciale d’un dépistage précoce, d’une intervention rapide et d’un accès équitable aux
capacités de laboratoire. Les systèmes centralisés se sont souvent révélés
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insuffisants, notamment
dans les zones reculées ou mal desservies, entraînant des retards dans la confirmation des cas et
réduisant l’efficacité des mesures de contrôle des épidémies.
La décentralisation des capacités de laboratoire constitue une stratégie transformative pour combler
ces lacunes. En rapprochant les examens diagnostiques des points de prestation de soins, les États
Membres de l’Union Africaine peuvent détecter les épidémies plus tôt, réagir plus efficacement et
renforcer la confiance du public dans les systèmes de santé.
Ce document propose un cadre global pour aider les États Membres à concevoir, mettre en œuvre
et pérenniser des réseaux de diagnostic décentralisés. Il met l’accent sur l’équité, l’appropriation
nationale, la collaboration multisectorielle et l’intégration avec les autres fonctions du système de santé.
De plus, il souligne l’importance du maintien des normes de qualité dans les contextes décentralisés,
en recommandant la mise en place de dispositifs de contrôle qualité adaptés, de mécanismes de
supervision ciblés et l’harmonisation avec les cadres nationaux d’assurance qualité.
Africa CDC, l’OMS et leurs partenaires restent déterminés à soutenir les États Membres à travers une
assistance technique, des plateformes de coordination et la mobilisation de ressources. Ensemble,
nous pouvons bâtir un écosystème de diagnostic résilient, réactif et inclusif, protégeant la santé de
toutes les communautés africaines.
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The lack of an African research ethics framework during epidemic emergencies (EE) has been a glaring concern
amongst African scholars for decades. In the context of major public health emergencies of continental and global health concern over the last five years, such as Ebola in 2019, COVID in 202
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0 and Mpox in 2024, and ongoing epidemics, including those of pandemic potential, the need for such a framework is evident. Ethics frameworks for research during emergencies have been published (World Health Organisation, 2016; Nuffield Council on Bioethics, 2020). However, there is currently no African and continent-wide, coherent guidance that promotes African values, elaborated by Africans for hosting research during EE on the continent. To address this gap, the African Centre for Disease Control convened an Ethics Working Group (Ethics WG) to develop an African
framework that embraces dominant African principles/values that might guide the ethical conduct of research in
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The Marburg Virus Disease (MVD) Response Plan outlines Tanzania’s national strategy for responding to a Marburg virus outbreak declared in the Kagera Region in January 2025. The document describes the current epidemiological situation, assesses the risks posed by the outbreak, and sets strategic o
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bjectives to contain the disease and prevent further transmission. It details response measures across multiple sectors, including surveillance, laboratory testing, case management, infection prevention and control, risk communication, logistics, and community engagement. Furthermore, the plan defines coordination mechanisms, operational procedures, monitoring indicators, and the financial resources required to implement the response. Overall, the plan serves as a comprehensive framework to guide national and international stakeholders in controlling the outbreak and protecting public health.
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Between April 2018 and November 2020, the Democratic Republic of Congo (DRC) experienced its 11th Ebola virus disease (EVD) outbreak. Tanzania’s cross-border interactions with DRC through regular visitors, traders, and refugees are of concern, given the potential for further spread to neighboring
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countries. This study aimed to estimate the risk of introducing EVD to Tanzania from DRC. National data for flights, boats, and car transport schedules from DRC to Tanzania covering the period of May 2018 to June 2019 were analyzed to describe population movement via land, port, and air travel and coupled with available surveillance data to model the risk of EVD entry. The land border crossing was considered the most frequently used means of travel and the most likely pathway of introducing EVD from DRC to Tanzania. High probabilities of introducing EVD from DRC to Tanzania through the assessed pathways were associated with the viability of the pathogen and low detection capacity at the ports of entry. This study provides important information regarding the elements contributing to the risk associated with the introduction of EBV in Tanzania. It also indicates that infected humans arriving via land are the most likely pathway of EBV entry, and therefore, mitigation strategies including land border surveillance should be strengthened.
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Les maladies infectieuses peuvent se transmettre lorsqu'une personne non contaminée est en contact avec les liquides organiques d'une personne contaminée décédée.
La dimensión ambiental y los esfuerzos para combatir el cambio climático forman parte de la estrategia que propone la Comisión Económica para América Latina y el Caribe (CEPAL) para lograr el desarrollo sostenible en América Latina y el Caribe y enfrentar las trampas que obstaculizan el progre
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so: baja capacidad para crecer; alta desigualdad, baja movilidad social y débil cohesión social, y bajas capacidades institucionales y gobernanza poco efectiva.
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Links to to summarised versions of Cochrane Reviews from EPOC and other groups that may be of particular relevance in pandemic situations such as COVID-19:
Inclusive Project Cycle Management
