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This study investigated occupational risk factors and exposure–response relationships for airway disease among health workers (HWs) exposed to cleaning agents in two tertiary hospitals in South Africa and Tanzania.
Previous studies have demonstrated an association between asthma or respiratory
...
symptoms and exposure to broad categories of cleaning-related exposures in healthcare settings. However, few studies have identified the specific cleaning agents responsible for asthma and other health outcomes. Products used for medical instrument cleaning and disinfection such as glutaraldehyde, orthophthalaldehyde (OPA) and quaternary ammonium compounds (QACs) have been implicated in the causation and exacerbation of work-related asthma (WRA) and upper airway outcomes such as rhinitis.
more
The Mediclinic article on silicosis provides an overview of this occupational lung disease caused by inhaling silica dust. It explains that inhaled silica particles lead to lung scarring and nodule formation, progressively impairing breathing. The article outlines symptoms such as shortness of breat
...
h, severe cough, fatigue, loss of appetite, chest pains, and fever. Diagnosis involves a medical examination, detailed occupational history, lung function tests, and imaging like chest X-rays or CT scans to detect lung scarring and nodules. While silicosis is irreversible with no specific cure, management focuses on preventing further silica exposure and treating complications. Preventive measures include maintaining high occupational health standards to control silica dust exposure.
more
The document "Cystic Fibrosis Key Findings 2023 for Care Providers" by the Pennsylvania Department of Health summarizes recent findings and insights related to cystic fibrosis (CF). It highlights key statistics on the prevalence and outcomes of CF, emphasizes best practices for patient care, and pro
...
vides recommendations for healthcare providers. The document discusses improvements in treatment protocols, advances in medical research, and strategies to enhance patient quality of life. It also includes guidance on early detection, genetic testing, and comprehensive management plans to support affected individuals and their families.
more
The Cedars-Sinai webpage on occupational lung diseases provides an overview of various lung conditions caused by exposure to harmful substances in the workplace. It outlines common types of occupational lung diseases, including asbestosis, silicosis, coal workers’ pneumoconiosis, and chemical-rela
...
ted lung disorders. The page details symptoms such as coughing, difficulty breathing, and chest pain, emphasizing the importance of early detection and treatment. Preventative measures, including workplace safety practices and protective equipment, are also highlighted to reduce risk. The information underscores the role of medical evaluation and ongoing management for individuals exposed to occupational hazards.
more
About Cystic Fibrosis - What is Cystic Fibrosis?
South Africa Cystic Fibrosis Association (SACFA)
South African Cystic Fibrosis Association (SACFA)
(2024)
CC2
The South African Cystic Fibrosis Association (SACFA) is a non-profit organization dedicated to supporting individuals with cystic fibrosis (CF) in South Africa. Their website provides comprehensive information about CF, including its causes, symptoms, and treatment options. CF is described as an in
...
herited genetic disorder that primarily affects the lungs and pancreas, leading to the production of thick, sticky mucus that can cause severe respiratory and digestive issues. The site emphasizes the importance of early diagnosis and proper management to improve the quality of life for those affected. Additionally, SACFA outlines its mission to raise public awareness, promote medical advancements, and offer support to the CF community through various initiatives and resources.
more
The Mediclinic Infohub article on silicosis provides an overview of this occupational lung disease caused by inhaling silica dust. It explains that inhaled silica particles lead to lung scarring and nodule formation, progressively impairing breathing. The article outlines symptoms such as shortness
...
of breath, severe cough, fatigue, loss of appetite, chest pains, and fever. Diagnosis involves a medical examination, detailed occupational history, lung function tests, and imaging like chest X-rays or CT scans to detect lung scarring and nodules. While silicosis is irreversible with no specific cure, management focuses on preventing further silica exposure and treating complications. Preventive measures include maintaining high occupational health standards to control silica dust exposure.
more
Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review
Iheanacho, I.; Zhang, S.; King, D.; et al.
International Journal of Chronic Obstructive Pulmonary Disease
(2022)
CC2
The article "Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review" examines the financial impact associated with moderate-to-very severe COPD. The review analyzes studies published between 2006 and 2016 that discuss healthcare resource utilization (HRU), di
...
rect costs, and indirect costs related to COPD, with a focus on Europe and North America. It highlights that direct costs, including hospitalizations and medical treatments, increase with the severity of COPD and the frequency of exacerbations. Multivariate analyses identify key factors driving these costs, such as comorbidities and prior treatment history. The findings underscore the significant economic burden of COPD on healthcare systems and emphasize the need for improved management strategies to reduce costs and optimize patient care.
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The document provides information on managing chronic obstructive pulmonary disease (COPD). It emphasizes the importance of recognizing early symptoms such as persistent coughing, shortness of breath, and wheezing. The guide offers practical advice, including quitting smoking, avoiding lung irritant
...
s, regular consultations with healthcare providers, and seeking support from friends and caregivers. It also highlights the value of preparing for medical visits, noting symptoms, understanding risk factors, and taking notes during appointments to maximize treatment effectiveness.
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What You Can Do About a Lung Disease Called COPD
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
Global Initiative for Chronic Obstructive Lung Disease (GOLD)
(2019)
CC2
The "GOLD Patient Guide 2019" explains Chronic Obstructive Pulmonary Disease (COPD), its causes, symptoms, and stages. It provides practical advice for managing COPD, including the importance of quitting smoking, following medical treatment plans, e
...
xercising, maintaining a healthy diet, and creating a supportive living environment. The guide emphasizes early diagnosis, regular medical checkups, and strategies for managing severe COPD to improve quality of life.
more
Read me – About the Health Financing Toolbox
recommended
The Health Financing Toolbox is designed to equip development cooperation stakeholders with essential information on the internal and external financing of nation states, with a particular emphasis on health financing. To achieve this, the Health Financing Toolbox includes a comprehensive collection
...
of topic-specific documents, along with numerous interactive world maps and data tables. These digital tools enable users to explore key aspects of health financing across all countries, with data categorized into both economic and medical dimensions.
more
Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu
...
s diagnoses by three pediatricians who were guided by study definitions that were based on medical history, physical examination findings, laboratory and radiological tests, and response to bronchodilators. Children with asthma or bronchiolitis were categorized as “asthma syndrome”. Using this approach, 253 (41.2%) had asthma syndrome. History of and present breathing difficulties and present cough and wheezing was the best performing combination of four questionnaire items [sensitivity 80.8% (95% CI 77.6–84.0); specificity 84.7% (95% CI 81.8–87.6)]. The screening tool for asthma syndrome in ‘under-fives’ may provide a simple, cheap and quick method of identifying children with possible asthma. The validity and reliability of this tool in primary care settings should be tested.
more
he aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and allergic disease, by establishing a standardized m
...
ethodology and facilitating international collaboration. Its specific aims are: 1) to describe the prevalence and severity of asthma, rhinitis and eczema in children living in different centres, and to make comparisons within and between countries; 2) to obtain baseline measures for assessment of future trends in the prevalence and severity of these diseases; and 3) to provide a framework for further aetiological research into genetic, lifestyle, environmental, and medical care factors affecting these diseases. The ISAAC design comprises three phases. Phase 1 uses core questionnaires designed to assess the prevalence and severity of asthma and allergic disease in defined populations. Phase 2 will investigate possible aetiological factors, particularly those suggested by the findings of Phase 1. Phase 3 will be a repetition of Phase 1 to assess trends in prevalence.
more
The global burden of asthma: executive summary of the GINA Dissemination Committee report
Masoli, M.; Fabian, D.; Holt, S.; Beasley, R.
European Journal of allergy and clinical immunology: Volume59, Issue5 May 2004 Pages 469-478
(2004)
CC2
It is estimated that as many as 300 million people of all ages, and all ethnic backgrounds, suffer from asthma and the burden of this disease to governments, health care systems, families, and patients is increasing worldwide. In 1989 the Global Initiative for Asthma (GINA) program was initiated in
...
an effort to raise awareness among public health and government officials, health care workers, and the general public that asthma was on the increase. The GINA program recommends a management program based on the best available scientific evidence to provide effective medical care for asthma tailored to local health care systems and resources.
more
Read about our flagship publication, The Global Asthma Report 2022, a 102-page cutting edge State-of-the-Art report, with contributions from 97 experts from, 31 countries.
The theme for this year is "Asthma Education Empowers", and emphasizes the need to empower people with asthma with the approp
...
riate education to manage their disease, and to recognize when to seek medical help.
more
This threat assessment addresses the implications of the ongoing Marburg virus disease (MVD) outbreak in
Rwanda for the European Union/European Economic Area (EU/EEA). MVD is a severe disease in humans and,
although uncommon, it has the potential to cause epidemics with significant case fatality.
...
All recorded MVD
outbreaks to date have originated in Africa. MVD is not an airborne disease and is considered not to be
contagious before symptoms appear. Direct contact with the blood and other body fluids of infected people
and animals or indirect contact with contaminated surfaces and materials like clothing, bedding and medical
equipment is required for transmission. The risk of infection is minimised when proper infection prevention and
control precautions are strictly followed. There is no approved treatment or vaccine for MVD; however, several
pharmaceuticals and candidate MVD vaccines are under investigation.
more
The video titled "Ganemos tiempo: podría ser tuberculosis" (Let's save time: it could be tuberculosis) is part of a public health campaign aimed at raising awareness about tuberculosis (TB). It emphasizes the importance of early detection and timely treatment to combat the disease effectively. The
...
video highlights common symptoms of TB, such as persistent cough, weight loss, and fever, and encourages individuals experiencing these signs to seek medical attention promptly. By doing so, it aims to reduce transmission rates and improve health outcomes.
more
Health communication has proven to play a crucial role in addressing diseases such as dengue, Zika and chikungunya, for which there are no definitive or easily accessible vaccines. In this context, this discipline becomes a fundamental tool to promote the change behavior and promote preventive pract
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ices that reduce the transmission of these diseases. By not having a definitive medical solution, accurate and timely information, effectively disseminated through educational campaigns, media and communication channels public health, can significantly influence individual and community actions to control the spread of these mosquito-borne viruses. The accumulated research around the threat of the aforementioned arboviral diseases brings together a series of recommendations around specific communication activities, such as disseminating timely and accurate information that integrates public health concerns and the needs of information of the population, especially vulnerable groups such as women of childbearing age, pregnant women and health workers.
more
The World Health Organization (WHO) African Region website provides comprehensive information on cholera outbreaks across the continent. In 2024, 14 countries, including the Democratic Republic of the Congo, Ethiopia, and Nigeria, experienced significant outbreaks, with these three nations categoriz
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ed as being in acute crisis.
The site offers access to Monthly Regional Cholera Bulletins, such as the May 2024 edition, which details the status of outbreaks, affected countries, and response measures.
Additionally, the website emphasizes the importance of coordinated responses to cholera outbreaks, highlighting efforts to enhance surveillance, provide medical supplies, and implement vaccination campaigns in high-risk areas.
Overall, the WHO African Region's cholera page serves as a vital resource for understanding the scope of cholera outbreaks and the ongoing initiatives to control and prevent the disease across the continent.
more
Buruli ulcer is a disease caused by the environmental pathogen Mycobacterium ulcerans that affects skin and soft tissue. It was first described in Australia in 1948 and has been reported in several sub-Saharan African countries since the late 19th century. The disease mainly affects children in rura
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l areas and causes lesions and ulcers that can lead to disability if not treated. Recent research has identified a toxin produced by M. ulcerans that may be responsible for the disease's pathogenesis. Efforts are ongoing to understand transmission and develop effective control strategies, including through training of medical professionals and increased detection and treatment of cases.
more
The article "Malaria – MSD Manual Professional Edition" provides a comprehensive overview of malaria, an infection caused by Plasmodium species. It describes symptoms such as fever, chills, and anemia, explains diagnostic methods like parasite detection in blood smears, and discusses treatment opt
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ions including artemisinin-based combination therapies. In addition, it outlines prevention strategies such as medical prophylaxis and mosquito control measures. The article is intended for medical professionals and offers detailed information on the pathophysiology, clinical presentation, and management of malaria.
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