Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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El propósito general de la reunión fue analizar la interrelación entre la salud, la nutrición y el desarrollo infantil, dentro del marco de la “Estrategia Global para la Alimentación y Nutrición del Infante y Niño Pequeño” (OMS/UNICEF).
This study addresses part of the Terms of Reference for a scoping report ‘An analysis of approaches to laboratory capacity strengthening for drug resistant infections in low and middle income countries’. It has been produced as a separate report because it is also very relevant for a second stud...y ‘Supporting Surveillance Capacity for Antimicrobial Resistance: Regional Networks and Educational Resources’. This study compares antimicrobial surveillance systems in three low and middle income countries in order to describe the components of these systems and to understand which surveillance models are best suited to particular contexts. Ghana, Nigeria and Nepal were selected as study countries because they cover different continents and include one ‘fragile’ context (Nigeria). Brief information from Malawi is also included.
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La Commission européenne contre le racisme et l'intolérance (ECRI) a été créée par le Conseil de l'Europe. C'est un organisme indépendant qui veille au respect des droits de l'homme dans la lutte contre le racisme, la discrimination (fondée sur la "race", l'origine ethnique ou nationale, la ...couleur, la nationalité, la religion, la langue, l'orientation sexuelle et l'identité de genre), la xénophobie, l'antisémitisme et l'intolérance. Les membres de la Commission sont indépendants et impartiaux. Ils sont nommés sur la base de leur autorité morale et de leur expertise reconnue en matière de racisme, de xénophobie, d'antisémitisme et d'intolérance. Dans le cadre de son mandat statutaire, l'ECRI produit des rapports nationaux pour chaque pays qui analysent la situation en matière de racisme et d'intolérance dans chaque Etat membre du Conseil de l'Europe et font des propositions pour résoudre les problèmes identifiés.
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A manual for impact assessments. The SCH Practical and Precision Assessment (SPPA) strategy is an evidence-based approach for conducting impact assessments for SCH. The SPPA was identified by programme managers and SCH experts from the African region as a feasible and sufficiently accurate approach ...after reviewing and discussing the results of a multi-country study. This manual describes the resulting Practical and Precision Assessments approach and includes a discussion of the underlying concepts, factors to consider when determining what approach is appropriate, and how to interpret the collected data. The manual also includes annexes with standard operating procedures for conducting the stool and urine analyses.
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Médicaments et dispositifs médicaux pour une population de
10 000 personnes pendant environ 3 mois
The objective of this paper is to summarise and critically review the available data about onchocerciasis in Mozambique, in order to report epidemiological and clinical aspects related to the disease and identify gaps in knowledge. The paper is intended to raise awareness of the existence and import...ance of this disease and to define research priorities
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PLoS Med 16(3): e1002768. https://doi.org/10.1371/journal.pmed.1002768
Home delivery and late and infrequent attendance at antenatal care (ANC) are responsible for substantial avoidable maternal and pediatric morbidity and mortality in sub-Saharan Africa. This cluster-randomized trial aimed to de...termine the impact of a community health worker (CHW) intervention on the proportion of women who visit ANC fewer than 4 times during their pregnancy and deliver at home.
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BMC Health Services Research BMC series – open, inclusive and trusted201818:251; https://doi.org/10.1186/s12913-018-3072-3
23 February 2021
This document describes the medical devices required for the clinical management of COVID-19, selected and prioritized according to the latest available evidence and interim guidelines. This includes: oxygen therapy, pulse oximeters, patient monitors, thermometers, infusion and suc...tion pumps, X-ray, ultrasound and CT scanners as well as personal protective equipment. In order to facilitate access to quality assured priority medical devices, the document also includes technical and performance characteristics, related standards, accessories and consumables. It is intended for policy-makers and planning officers in Ministries of Health, procurement and regulatory agencies, intergovernmental and international agencies as well as the medical device industry.
This document is an update to the List of priority medical devices for COVID-19 case management and Technical specifications for invasive and non-invasive ventilators for COVID-19.
This document complements the Technical specifications of personal protective equipment for COVID-19.
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Provide guidance to HIV care practitioners on the optimal use of antiretroviral (ARV) agents for the treatment of HIV infection in adults and adolescents.
Supplement October 2010
HIV/AIDS, security and conflict: making the connections
The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.
Informe sobre poblaciones clave
Au cours des dix années à venir, la Fédération internationale œu
vrera, collectivement, à la réalisation des objectifs stratégiques
suivants:
1. Sauver des vies, protéger les moyens d’existence et renforcer
le relèvement après les catastrophes et les crises
2. Promouvoir des modes ...de vie sains et sûrs
3. Promouvoir l’intégration sociale et une culture de non-violenceet de paix.
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