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Advances in preclinical approaches to Chagas disease drug discovery

Villalta, F.; Rachakonda, G. (2019) CC
Chagas disease affects 8-10 million people worldwide, mainly in Latin America. The current therapy for Chagas disease is limited to nifurtimox and benznidazole, which are effective in treating only the acute phase of the disease but with severe side ... more
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The many faces of diabetes. Is there a need for re-classification? A narrative review

Sakran, N.; Graham, Yiitka.; Pintar, T.; et al. BMC Endocrine Disorders Volume 22 Article Number 9 (2022) CC
The alarming rise in the worldwide prevalence of obesity and associated type 2 diabetes mellitus (T2DM) have reached epidemic portions. Diabetes in its many forms and T2DM have different physiological backgrounds and are difficult to classify. Baria ... more
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The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 680 102 adults

Flood, D.; Seiglie, J.A.; Dunn, M.; et al. The Lancet healthy Longevity (2021) C2
Approximately 80% of the 463 million adults worldwide with diabetes live in low-income and middle-income countries (LMICs). A major obstacle to designing evidence-based policies to improve diabetes outcomes in LMICs is the scarce availability of nat ... more
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Global report on health equity for persons with disabilities

World Health Organization WHO (2022) C_WHO
An estimated 1.3 billion people – or 16% of global population worldwide – experience a significant disability today. Persons with disabilities have the right to the highest attainable standard of health as those without disabilities. However, th ... more
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The Global Burden of Cardiovascular Diseases and Risk: A Compass for Future Health

Vaduganathan, M.; Mensah, G.A.; Turco, J.V. et al. Journal of the American College of Cardiology (2022) CC
Cardiovascular diseases (CVDs) have collectively remained the leading causes of death worldwide and substantially contribute to loss of health and excess health system costs. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study has ... more
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“Chagas Express XXI”: Anew ArtScience social technology for health and science education

Araujo-Jorge, T.; Ferreia, R.; Rocha, R. PLoS Neglected Tropical diseases (2021) CC
Chagas Disease (CD) affects 6–7 million people worldwide and isrelated topoverty-promo ting conditions. Chronic asymptomatic cases are mostly invisible tohealth systems. Aiming totranslate CD discoveries into education/information practices torais ... more
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Antimicrobial resistance and access to antibiotics

World Health Organization WHO EMHJ – Vol. 30 No. 12 – 2024 (2024) C_WHO
It is estimated that around 2 billion people worldwide do not have access to essential medicines. Access to medicines in the Eastern Mediterranean Region varies among countries, depending on their income level and allocation of domestic resources to ... more
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Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial

Biccard, B.M.; V. Msosa, A.L Samateh et al. TheLancet (2021) CC
Surgical site infection (SSI) is the most common postoperative complication worldwide. WHO guidelines to prevent SSI recommend alcoholic chlorhexidine skin preparation and fascial closure using triclosan-coated sutures, but called for assessment of ... more
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Soil-transmitted helminthiases (STH)

World Health Organization World Health Organization WHO (2022) C_WHO
Soil-transmitted helminth (STH) infections are among the most common infections worldwide and affect the poorest and most deprived communities. They are transmitted by eggs present in human faeces which in turn contaminate soil in areas where sanita ... more
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Network of WHO Collaborating centers for trachoma

World Health Organization World Health Organization WHO (2016) C_WHO
International commitment to eliminate trachoma as a public health problem worldwide is supported by resolution WHA51.11 of the World Health Assembly .1 Important progress towards this goal has been made by harnessing the mostly informal relationship ... more
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An estimate of asthma prevalence in Africa: a systematic analysis

Adeloye, D.; Chan, K. Y.; Rudan, I.; Campell, H. National Library of Medicine (2013) CC2
Chronic respiratory diseases (CRDs) are among the leading causes of death worldwide, with asthma rated the most common chronic disease affecting children (1). Globally, about 300 million people have asthma, and current trends suggest that an additio ... more
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Global Burden of Disease (GBD). The Lancet

(2019) CC
The Global Burden of Disease Study (GBD) is the most comprehensive worldwide observational epidemiological study to date. It describes mortality and morbidity from major diseases, injuries and risk factors to health at global, national and regional ... more
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Trachoma Key facts

World Health Organization World Health Organization WHO (2022) C_WHO
Trachoma is the leading infectious cause of blindness worldwide. It is caused by an obligate intracellular bacterium called Chlamydia trachomatis. The infection is transmitted by direct or indirect transfer of eye and nose discharges of infected peo ... more
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Cholera prevention, control strategies, challenges and World Health Organization initiatives in the Eastern Mediterranean Region: A narrative review

Buliva E., Elnossery S., Okwarah P. et al. Heliyon (2023) C2
Cholera remains a significant public health threat in many countries worldwide. In resource-constrained settings, it disproportionately affects thousands of poor and vulnerable population
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Rehabilitation 2030: A Call for Action

World Health Organization WHO (2018) C_WHO
There is a substantial and ever-increasing unmet need for rehabilitation worldwide, which is particularly profound in low- and middle -income countries. The availability of accessible and affordable rehabilitation is necessary for many people with ... more
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Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme

Cooper, P. J.; Figueiredo, C. A.; Rodriguez, A.; et al. (2023) CC2
Asthma is the most common chronic respiratory disease (CRD) worldwide and is estimated to affect 262 million causing significant mortality and morbidity, and has emerged as an important public health problem in many Latin American (LA) countries ove ... more
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COP24 special report: health and climate change
recommended

World Health Organization WHO WHO (2018) C_WHO
Exposure to air pollution causes 7 million deaths worldwide every year and costs an estimated US$ 5.11 trillion in welfare losses globally. In the 15 countries that emit the most greenhouse gas emissions, the health impacts of air pollution are esti ... more
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Vaccines/COVID-19 vaccine EUL issued

World Health Organization WHO (2022) C_WHO
This chronology of facts has challenged public health systems worldwide and regulatory bodies are no exception. Regulatory authorities with mechanisms in place to authorize the use of investigational products had to development guidelines and proced ... more
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Rapport mondial sur l’équité en santé pour les personnes handicapées : résumé d’orientation

World Health Organisation (WHO) (2022) C_WHO
An estimated 1.3 billion people – or 16% of global population worldwide – experience a significant disability today. Persons with disabilities have the right to the highest attainable standard of health as those without disabilities. However, th ... more