The Knowledge Translation Unit is a group within the University of Cape Town’s Lung Institute and Department of Medicine who has worked on primary care programmes to strengthen provision of evidence-informed care in low-resources settings in South Africa, Ethiopia, Nigeria and Brazil for two decad...es. See here for more information. We are working around the clock to help health workers in these and similar settings to manage the COVID-19 pandemic. These can be accessed below. We are also working to expand these to support primary healthcare workers, patients and households. You can also access our free online training.
For purposes of assisting communities during the COVID-19 pandemic, we are making our COVID-19 and related materials freely available for others to use subject to some simple conditions.
more
COVID-19 has triggered the deepest global recession since the 1930s. Extreme poverty has risen for the first time in 22 years, and unemployment has increased dramatically. Women and young people aged 15 – 29 working in the informal sector are being hit the hardest. School closures have affected 91... per cent of students worldwide.
Political conflicts are more intense and taking a heavy toll on civilians, disproportionately affecting children. Women and girls are at increased risk of conflict-related sexual violence. Attacks against aid and health workers persist. For the ninth consecutive year, more than 90 per cent of casualties from explosive weapons in populated areas were civilians.
The last decade saw the highest-ever number of people internally displaced by conflict and violence, with many locked in a state of protracted displacement. There are an estimated 51 million new and existing IDPs, and the number of refugees has doubled to 20 million.
more
sobre la base de las orientaciones actuales de la OMS, 31 de mayo de 2021. Memorando
This aide-mémoire presents information on use and procurement of masks for community outreach interventions, with a focus on those for malaria, neglected tropical diseases, tuberculosis, HIV/AIDS and vaccine-preve...ntable diseases. It details requirements for the different types of professionals involved (e.g. health workers, social mobilizers, data collectors, logisticians, insecticide spraying personnel, etc.), based on their level of risk of potential exposure to SARS-CoV-2.
more
The marathon to eradicate polio is on its final lap: the world is more than 99% of the way to success. After millennia of living with poliovirus and suffering the paralysis it causes, today nearly all the world’s people live in polio-free countries; two of the three strains of wild poliovirus (WPV...) have been eradicated. Some 20 million people are walking who would have been paralysed had it not been for the efforts of national governments and health workers. If eradicating polio has been a marathon, the finishing line is in sight.
more
Cardiovascular diseases, principally ischemic heart disease (IHD), are the most important cause of death and disability in the majority of low- and lower-middle-income countries (LLMICs). In these countries, IHD mortality rates are significantly greater in individuals of a low socioeconomic status (...SES).
Three important focus areas for decreasing IHD mortality among those of low SES in LLMICs are (1) acute coronary care; (2) cardiac rehabilitation and secondary prevention; and (3) primary prevention. Greater mortality in low SES patients with acute coronary syndrome is due to lack of awareness of symptoms in patients and primary care physicians, delay in reaching healthcare facilities, non-availability of thrombolysis and coronary revascularization, and the non-affordability of expensive medicines (statins, dual anti-platelets, renin-angiotensin system blockers). Facilities for rapid diagnosis and accessible and affordable long-term care at secondary and tertiary care hospitals for IHD care are needed. A strong focus on the social determinants of health (low education, poverty, working and living conditions), greater healthcare financing, and efficient primary care is required. The quality of primary prevention needs to be improved with initiatives to eliminate tobacco and trans-fats and to reduce the consumption of alcohol, refined carbohydrates, and salt along with the promotion of healthy foods and physical activity. Efficient primary care with a focus on management of blood pressure, lipids and diabetes is needed. Task sharing with community health workers, electronic decision support systems, and use of fixed-dose combinations of blood pressure-lowering drugs and statins can substantially reduce risk factors and potentially lead to large reductions in IHD. Finally, training of physicians, nurses, and health workers in IHD prevention should be strengthened.
more
COVID-19 has triggered the deepest global recession since the 1930s. Extreme poverty has risen for the first time in 22 years, and unemployment has increased dramatically. Women and young people aged 15 – 29 working in the informal sector are being hit the hardest. School closures have affected 91... per cent of students worldwide.
Political conflicts are more intense and taking a heavy toll on civilians, disproportionately affecting children. Women and girls are at increased risk of conflict-related sexual violence. Attacks against aid and health workers persist. For the ninth consecutive year, more than 90 per cent of casualties from explosive weapons in populated areas were civilians.
The last decade saw the highest-ever number of people internally displaced by conflict and violence, with many locked in a state of protracted displacement. There are an estimated 51 million new and existing IDPs, and the number of refugees has doubled to 20 million.
more
Welcome to the Lancet COVID-19 Resource Centre, bringing together all COVID-19 research, reviews, commentary, news, and analysis from across the Lancet family of journals as it is published. The resource aims to assist health workers, policy makers, and researchers to bring the COVID-19 pandemic to ...a close. All of our COVID-19 content is free to access.
more
Please find all relevant guidelines and information in our new Pharmacy Toolbox.
The PHARMACY TOOLBOX is a comprehensive knowledge repository to provide its users with practical, up-to-date information on medicines and good pharmaceutical practices. It collates basic documents on (essential) medici...nes, guidelines, rational use, access, and good quality of medicines. All health workers who prescribe, handle or dispense medicines find an electronic key pharmacy knowledge hub.
more
As slight hints of recovery begin to surface in West Africa, UNICEF is looking at the impact of Ebola on children and the response and work of the affected communities in the report, Ebola: Getting to zero – for communities, for children for the future. The document traces some of the outbreak’s... history along with the stories of survivors, health care workers and those working to make things better on the ground. The report also helps map out the actions that urgently must continue to help build resiliency and resuscitate basic services and systems decimated by Ebola.
more
The PDF "Vamos proteger-nos da Cólera" provides comprehensive guidance on cholera prevention and response strategies, particularly for use in community health settings. It emphasizes the importance of safe water use by treating water with bleach, boiling it for at least 5 minutes, or using purifica...tion tablets like Aquatabs. Handwashing is highlighted as a key measure, especially after using the latrine, before preparing food, and before eating. Sanitation practices include using and maintaining clean latrines or, if unavailable, burying feces far from homes and water sources.
The document also addresses diarrhea treatment, recommending the preparation and use of Oral Rehydration Solution (ORS) with added zinc for effective recovery. It encourages breastfeeding for infants with diarrhea and stresses the importance of cooking food thoroughly, keeping it covered, and ensuring all utensils and surfaces are clean. Proper waste management, including the disposal of household waste, is highlighted to maintain a clean and safe environment.
In emergency situations, the guide advises seeking immediate medical attention for severe diarrhea and emphasizes the prompt burial of bodies during outbreaks to prevent contamination. Additionally, it provides visuals and strategies for community engagement, empowering health workers and communities to promote awareness and adopt effective cholera prevention measures.
more
The "Hygiene Awareness Manual" focuses on promoting improved hygiene practices within communities, emphasizing personal and household hygiene, water safety, and environmental health. It highlights the importance of handwashing, oral hygiene, and maintaining cleanliness of the skin and clothing as ke...y aspects of personal and family hygiene. Specific practices such as regular bathing and wearing clean clothes are also emphasized.
For household hygiene, the manual provides guidance on safe food preparation and storage, as well as keeping living spaces, kitchens, and latrines clean to prevent contamination. It also addresses water safety, emphasizing the need to store water in clean containers, treat it for safe consumption, and dispose of wastewater properly to avoid environmental contamination.
The manual underscores the significance of balanced nutrition and food safety, offering guidelines for cooking and preserving food to reduce health risks. It also delves into disease prevention, explaining the causes and transmission of waterborne and hygiene-related diseases, such as cholera and dysentery, and outlining effective methods to prevent them through proper sanitation and hygiene.
This comprehensive guide serves as a practical resource for community health workers and households, aiming to foster better hygiene practices, prevent diseases, and enhance overall health and well-being.
more
For full publication see: https://drtbnetwork.org/mdr-tb-patient-education-flipchart
This tool can be used to educate new patients about TB and MDR-TB. The healthcare provider should review the material together with the patient. A treatment supporter can also use this flipchart at community lev...el to reinforce the concepts covered.
Major concepts covered in the flipchart:
TB is a contagious disease, which means it can be spread from person to person.
TB generally lives in the lungs, but it can also infect other parts of the body.
If TB is left untreated, it can kill the patient.
TB can be cured with the right medicine.
The flipchart can be adapted and modified as needed. The Mongolian Anti-Tuberculosis Association has adapted the flipchart for use in physician counseling training and in training of community health workers providing home-based care.
more
This page presents all our content related to COVID-19. It aims to: 1. Help people who want to understand or work on COVID-19 right now. 2. Help people who are considering biosecurity careers longer term.
This page will focus on leveraged opportunities in research, policy, technology and startups. ...Many people will find their best opportunities to help in their local community – supporting health workers, driving delivery vans, helping friends and family, looking after neighbours, and so on. If you already play a role in providing essential services it’s likely that working hard at your day job, while making efforts to avoid spreading the virus, is one of the most valuable things you can do.
more
Cardiovascular disease (CVD) is the leading cause of global deaths, with the majority occurring in low- and middle-income countries (LMIC). The primary and secondary prevention of CVD is suboptimal throughout the world, but the evidence-practice gaps are much more pronounced in LMIC. Barriers at the... patient, health-care provider, and health system level prevent the implementation of optimal primary and secondary prevention. Identification of the particular barriers that exist in resource-constrained settings is necessary to inform effective strategies to reduce the identified evidence-practice gaps. Furthermore, targeting modifiable factors that contribute most significantly to the global burden of CVD, including tobacco use, hypertension, and secondary prevention for CVD will lead to the biggest gains in mortality reduction. We review a select number of novel, resource-efficient strategies to reduce premature mortality from CVD, including: (1) effective measures for tobacco control; (2) implementation of simplified screening and management algorithms for those with or at risk of CVD, (3) increasing the availability and affordability of simplified and cost-effective treatment regimens including combination CVD preventive drug therapy, and (4) simplified delivery of health care through task-sharing (non-physician health workers) and optimizing self-management (treatment supporters). Developing and deploying systems of care that address barriers related to the above, will lead to substantial reductions in CVD and related mortality.
more
Many African countries were amongst the most rapid to respond to the emerging threat of COVID-19, implementing large-scale interventions at very early stages of their epidemic. As demonstrated in this document using very simple models, this rapid mobilization and timeliness of implementing control m...easures is likely to be an important determinant of their success. Indeed, as these measures were relaxed, subsequent waves of disease have been observed in many countries including South Africa, Kenya, Tunisia, Morocco, Sudan and the Democratic Republic of Congo (DRC) where such waves have severely impacted the health system by straining the supply of oxygen and ICU beds and inflicting a heavy toll on healthcare workers, often necessitating the re-imposition of control measures.
more
This core package of materials provides a comprehensive introduction to the FAST strategy: a focused approach to stopping TB spread in congregate settings. In English, FAST stands for:
Finding TB cases
Actively,
Separating safely, and
Treating effectively.
FAST focuses health care workers on ...the most important TB transmission control intervention: effective treatment.
FAST can also be extrapolated to national policy where it serves as a framework for allocating resources to interventions that will have the greatest impact on reducing TB transmission.
This core package is composed of a booklet, job aids, posters, and a button which serves as a visual reminder to staff and patients of the importance of this strategy in TB control. FAST can be implemented in both general and TB specific medical settings.
For full package visit: https://drtbnetwork.org/fast-tb-infection-control-strategy-core-package
more
This core package of materials provides a comprehensive introduction to the FAST strategy: a focused approach to stopping TB spread in congregate settings. In English, FAST stands for:
Finding TB cases
Actively,
Separating safely, and
Treating effectively.
FAST focuses health care workers on ...the most important TB transmission control intervention: effective treatment.
FAST can also be extrapolated to national policy where it serves as a framework for allocating resources to interventions that will have the greatest impact on reducing TB transmission.
This core package is composed of a booklet, job aids, posters, and a button which serves as a visual reminder to staff and patients of the importance of this strategy in TB control. FAST can be implemented in both general and TB specific medical settings.
For full package visit: https://drtbnetwork.org/fast-tb-infection-control-strategy-core-package
more
Evidence shows that oral pre-exposure prophylaxis (PrEP) reduces the risk of contracting HIV during sexual intercourse by more than 90% when taken daily. It is for this reason the National HIV Prevention Strategy 2015-2020 (2018 Revision) emphasises the role of preexposure prophylaxis (PrEP) in ...reducing new HIV infections in Malawi.
The Ministry of Health has prioritised PrEP use among the populations most at-risk of HIV infection in Malawi: young women ages 10 to 24 years, sero-discordant couples, female sex workers, men who have sex with men, and other priority populations (such as members of the uniformed services, prisoners, and mobile populations).
more
Clinical Presentation and Management for Haiti Cholera Outbreak, 2010
The document provides detailed guidelines for diagnosing and managing cholera cases, with a focus on rehydration therapy and preventing dehydration-related fatalities. It outlines the use of oral rehydration salts (ORS), intrav...enous fluids for severe dehydration, and appropriate antibiotics for severe cases. The guide also emphasizes the importance of hygiene, safe water usage, and monitoring patient recovery to effectively control cholera outbreaks. It is designed as a practical resource for healthcare workers and public health officials.
more
By the end of January 2020, UNHCR had created 25,664 places in the accommodation scheme as part of the ESTIA programme. These were in 4,606 apartments and 8 buildings, in 14 cities and 7 islands across Greece.
The Accommodation Scheme provides rented housing to vulnerable asylum-seekers and refug...ees in Greece. Urban accommodation helps restore a sense of normalcy and provides better access to services, including education and health. People are additionally supported by social workers and interpreters who help them access medical services, employment, language courses and recreational activities.
more