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1
Publication Years
3206
3668
414
29
2
1
1
Category
2981
459
269
263
211
101
78
3
Toolboxes
1941
745
420
350
274
190
176
153
145
136
129
121
91
77
73
65
64
64
57
54
47
31
20
18
6
1
Travelers planning to conduct humanitarian work in areas where outbreaks of Ebola hemorrhagic fever and Marburg hemorrhagic fever are known to occur need to be familiar with how Ebola virus and Marburg vir
...
us are transmitted
more
Ethical considerations for use of unregistered interventions for Ebola viral disease
World Health Organization
(2014)
West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus disease in history. On 11 August 2014, WHO convened a consultation where the participants concluded that in the particular context of the current Ebola outbre
...
ak in West Africa, it is ethically acceptable to offer unproven interventions that have shown promising results in the laboratory and in animal models but have not yet been evaluat-
ed for safety and efficacy in humans as potential treatment or prevention
more
Infection prevention and control (IPC) guidance summary
recommended
World Health Organization
(2014)
The summary of the infection prevention and control (IPC) measures is for anyone providing direct and non-direct care to patients with suspected or confirmed Ebola virus disease (EVD) in health-care facilities (HCFs). Essential IPC measures are also
...
included in the Table which can be used as a stand-alone tool.
more
Médecins Sans Frontières (MSF) Guidance App
recommended
For those with smartphones, you can install the free ‘MSF Guidance’ app by the Open Medicine Project from the app store. It includes the MSF guidelines on Ebola and Marburg virus disease. MSF guidance is an easily searchable app with all the la
...
test MSF clinical protocols and essential drug information for medical field workers. All content can be downloaded before mission and accessed at any time.
MSF Guidance for Android devices:
https://play.google.com/store/apps/details?id=org.msf.medical.guidelines&hl=en_US&gl=US
MSF Guidance for Apple devices:
https://apps.apple.com/si/app/msf-medical-guidelines/id1282995934
more
The Directorate General of Epidemiology announces the virtual self-instruction course:
"Vigilance, Prevential and Control of Ebola Virus Disease"
Interim Assessement Report
The EMA review was started by the Agency’s Committee for Medicinal Products for Human Use (CHMP) to support decision-making by health authorities. This first interim report includes information on seven experimental medicines intended for the treatment of people infecte
...
d with the Ebola virus:
BCX4430 (Biocryst);
Brincidofovir (Chimerix);
Favipiravir (Fujifilm Corporation/Toyama);
TKM-100802 (Tekmira);
AVI-7537 (Sarepta);
ZMapp (Leafbio Inc.);
Anti-Ebola F(ab’)2 (Fab’entech).
The amount of information available for the seven treatments is highly variable. For some compounds there is no data from use in human subjects available. A small number of treatments have been administered to patients in the current Ebola outbreak as compassionate use. Finally, there are also medicines included in this review that have already been studied in humans, albeit for the treatment of other viral diseases.
more
Key considerations for the implementation of Community Care Centres
World Health Organization
(2014)
Community Care Centres (CCCs) are small facilities (10 beds maximum), located within the community and run by community health workers. CCCs provide isolation facilities for Ebola patients in order to prevent further transmission of the virus within
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their households and communities. People with Ebola virus can also receive basic curative and palliative care in these centres in an environment supported by their family and communities. This document describes key principles and main considerations for implementation of a community approach.
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mBio, Vol. 6 Issue 2, March/April 2015
Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited number of studies. In this
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review, the authors address what we know and what we do not know about Ebola virus transmission. They also hypothesize that Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.
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The only way to prevent future Ebola epidemics of this magnitude is to address the fundamental social and political vulnerabilities that have allowed the virus to flourish, such as weak health systems and local services, poor governance, chronic pov
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erty, and a legacy of conflict and social divisions
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Recovering from the Ebola Crisis
Magdy Martínez-Solimán; Abdoulaye Mar Dieye; Izumi Nakamitsu et al.
United Nations, The World Bank, European Union and African Development Bank
(2015)
Full Report.
In response to a call by the United Nations Secretary-General and the Governments of Guinea, Liberia and Sierra Leone, an international team conducted an Ebola Recovery Assessment. The aim was to contribute towards laying the foundation for short-, medium- and long-term recovery while
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the medical emergency response continues to tackle the epidemic. This report is a contribution to ongoing efforts by the Governments of Guinea, Liberia and Sierra Leone to design their national Ebola virus disease recovery strategies
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The audit was undertaken in order to ascertain whether allocations and donations received directly by the Government of Sierra Leone, in the fight against the Ebola Virus Disease were utilised with due regard to economy and efficiency and that inter
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nal controls were observed accordingly. The audit found that more than US$ 10 million in spending was inadequately documented and US$ 6 million may have been diverted to non-existent or “ghost” workers. The Quote: “It makes one wonder how a serious humanitarian crisis was used as money-making machine,” said Ibrahim Tommy, coordinator for Sierra Leone’s Centre for Accountability and Rule of Law
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When Ebola hit Liberia in 2014, an atmosphere of fear and confusion contributed to the spread of the virus by making people unwilling to come forward for testing and treatment. Oxfam trained and equipped community health volunteers to go door-to-doo
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r, giving information and advice, encouraging anyone showing symptoms to go for tests, and keeping their family members informed about the progress of their treatment. The approach won the trust of communities and helped to slow the spread of the disease. This case study gives an overview of the programme, including aims, results and a personal story.
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Technical Update
Areas of Africa endemic for Buruli ulcer (BU), caused by Mycobacterium ulcerans, also have a high prevalence of human immunodeficiency virus (HIV), with adult prevalence rates between 1% and 5% (Maps). However, there is limited inf
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ormation on the prevalence of BU–HIV coinfection. Preliminary
evidence suggests that HIV infection may increase the risk of BU disease (1–3). In the Médecins Sans Frontières project in Akonolinga, Cameroon, HIV prevalence was approximately 3–6 times higher among BU patients than the regional estimated HIV prevalence (2). Similarly in Benin and Ghana, BU
patients were 8 times and 3 times respectively more likely to have HIV infection than those without BU (1, 3). Further study is needed to clarify this association and enhance knowledge about the prevalence ofBU–HIV coinfection in endemic areas.
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The strategy focuses on mobilizing and coordinating partners, experts and resources to help countries enhance surveillance of the Zika virus and disorders that could be linked to it, improve vector control, effectively communicate risks, guidance an
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d protection measures, provide medical care to those affected and fast-track research and development of vaccines, diagnostics and therapeutics
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The use of safe and efficacious insecticides against the adult and larval populations of mosquito vectors is one of the most effective ways to rapidly interrupt transmission of Zika virus, as well as other viruses transmitted by Aedes mosquitoes suc
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h as chikungunya and dengue.
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The World Health Organization has created a Zika app.
The app gathers all of WHO's guidance for agencies and individuals involved in the response to Zika Virus Disease and its suspected complications such as microcephaly, and for health care worker
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s such as doctors, nurses and community health workers.
Currently supported languages are English, Portuguese and Spanish. Please download directly from the iTunes Store.
Soon available in all the United Nations' official languages!
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WHO Zika App for Android
recommended
The World Health Organization has created a Zika app. The app gathers all of WHO's guidance for agencies and individuals involved in the response to Zika Virus Disease and its suspected complications such as microcephaly, and for health care workers
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such as doctors, nurses and community health workers. Currently supported languages are English, Portuguese and Spanish. Please download directly from the Google Play Store.
Soon available in all the United Nations' official languages!
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Plaza Sésamo: Si el Mosquito no te Pica, Adiós Zika! 2
Sesame Workshop
Unicef, Organización Panamericana de la Salud Organización Mundial de la Salud, Oficina Regional para las Américas
(2016)
Los "Muppets" de Plaza Sésamo Elmo y Raya están dando a conocer información importante sobre el zika y llamando la atención sobre la manera de reducir la propagación de virus que transmite el mosquito, y que hasta el momento se ha reportado en
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33 países y territorios de las Américas.
Los dos mensajes de servicio público de 30 segundos estarán disponibles en español e inglés, así como en portugués para el público de Brasil.
To view the video, please click on the external link.
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Plaza Sésamo: Si el Mosquito no te Pica, Adiós Zika! 1
Sesame Workshop
Unicef, Organización Panamericana de la Salud Organización Mundial de la Salud, Oficina Regional para las Américas
(2016)
Los "Muppets" de Plaza Sésamo Elmo y Raya están dando a conocer información importante sobre el zika y llamando la atención sobre la manera de reducir la propagación de virus que transmite el mosquito, y que hasta el momento se ha reportado en
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33 países y territorios de las Américas. Los dos mensajes de servicio público de 30 segundos estarán disponibles en español e inglés, así como en portugués para el público de Brasil.
To view the video, please click on the external link.
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PAHO has systematically identified and collected basic information on all investigations related to Zika, both those already published and those on track to be published.
Each study has been categorized in the areas of virus, vectors and reservoir
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s; epidemiology; disease pathogenesis and consequences of Zika infection; clinical management; public health interventions; health systems and services response; research and product development; and causality. You can also search by publication type: published articles, protocol and publication of preliminary results.
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