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Evidence summary: systematic review of oral fexinidazole as first line treatment for rhodesiense Human African Trypanosomiasis

World Health Organization WHO (2024) C_WHO
Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
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PICO questions, EtD tables, GDG recommendations

World Health Organization WHO (2024) C_WHO
WHO Guidelines for the Treatment of Human African Trypanosomiasis. Web Annex B
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Total fat intake for the prevention of unhealthy weight gain in adults and children: WHO guideline

World Health Organization WHO (2023) C_WHO
This guideline provides updated, evidence-informed guidance on the percentage of total fat in the diet to reduce the risk of unhealthy weight gain. This guideline is intended for a wide audience involved in the development, design and implementation of policies and programmes in nutrition and pub... more
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Criteria and procedures for the verification of elimination of transmission of "T. b. gambiense" to the human population in a given country

World Health Organization WHO (2023) C_WHO
Having established the goal of eliminating transmission of gambiense human African trypanosomiasis (g-HAT) to humans, the HAT-e-TAG considered which elements should be developed to assess this goal.
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Care of the Newborn Training Guide

Deborah Armbruster, Diana Beck, Susan Goldman, Phyllis Long SAVE THE CHILDREN (2005)
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Human African trypanosomiasis cases diagnosed in non-endemic countries (2011– 2020)

Franco. J.R.; G. Cecchi, G. Priotto, et al. (2022) CC
PLoS Negl Trop Dis 16(11): e0010885. https://doi.org/10.1371/journal.pntd.0010885 HAT diagnosis in non-endemic countries is rare and can be challenging, but alertness and surveillance must be maintained to contribute to WHO’s elimination goals. Early detection is particularly important as it co... more
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New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
recommended

Lindner A. K.; V. Lejon, M.P. Barrett, et al. (2025) CC
The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
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Eliminating Trachoma: Accelerating Towards 2020

World Health Organization WHO (2020) C_WHO
Trachoma is the world’s leading infectious cause of blindness. It is one of 18 neglected tropical diseases (NTDs) that affect over one billion of the world’s poorest people.
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Plague manual: epidemiology, distribution, surveillance and control Chapter 6-7

World Health Organization WHO (1999) C_WHO
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The End in sight: from collaboration to elimination

International Coaltion for Trachoma Control (2022) CC
ICTC’s 2022-2030 strategic plan spans the critical period running to the end of 2030, the year by which we are striving to achieve the elimination of trachoma as a public health problem. This strategic plan is in alignment with the NTD road map, Ending the neglect to attain the Sustainable Develop... more
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Zambia. Demographic and Health Survey 2018

Central Statistical Office (CSO) [Zambia], Ministry of Health (MOH) [Zambia], and ICF (2020) C1
Final Report
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Women and Trachoma: Achieving Gender Equity in the Implementation of SAFE

The Carter Center, International Trachoma Initiative and Kilimanjaro Centre for Community Ophthalmology (2023) CC
The second edition of the Women and Trachoma: Achieving Gender Equity in the Implementation of SAFE manual provides an updated resource for realistically increasing, improving, and supporting gender representation within trachoma elimination efforts at all levels. From the trachoma workforce to the ... more
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Kit de ferramentas de diagnóstico molecular do VIH para melhorar o acesso aos testes de carga virale e diagnóstico precoce pedátrico

World Health Organization WHO (2019) C_WHO
Intensificar o reforço das abordagens de monitorização do tratamento através dos testes da carga viral, assim como o diagnóstico pediátrico precoce, será fundamental para garantir cuidados e tratamentos de boa qualidade e o êxito dos programas. Considerar uma boa rede de diagnósticos, tipos... more
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Policy guidelines: Child and adolescent mental health

Department of Health, South Africa (2013) C2
The guidelines begin with an overview of the determinants of mental health among children and adolescents before reviewing related South African policies and legislation. The document then discusses strategies to build skills among caregivers, teachers and other frontline providers of mental health ... more
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Philippines: National Demographic and Health Survey 2003

National Statistics Office Manila, Philippines; ORC Macro International USAID (2004) C1
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Guidelines for Acute respiratory illness in Ghana

Ministry of Health Ghana; Ghana Health Service Ghana GIZ; BMZ; WHO (2013) C1
The Integrated Management of Adolescent/Adult Illness (IMAI) approach
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Delivery Mechanism Mapping for Cash Based Interventions (CBI) in Cox’s Bazar, Bangladesh, December 2017

Catholic Relief Services, European Commission's Directorate-General for European Civil Protection and Humanitarian Aid Operations, International Organization for Migration; et al. (2018) C1
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Positive health, dignity and prevention for women and their babies. Facilitator’s manual

Inter-Agency Task Team (IATT) (2018) C1
A treatment literacy guide for pregnant women and mothers living with HIV
Positive Health, Dignity and Prevention for Women and their Babies is intended for use by networks of women living with HIV, women’s groups, peer educators and others wishing to help guide women living with HIV t... more
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Diphtheria: NICD Recommendations for Diagnosis, Managementand Public Health Response

The National Institute For Communicable Diseases, South Africa (2018) C1