Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The diagnosis of asthma in young children is limited by the inability to perform objective lung function testing in this group of patients and the wi...de variety of conditions that can phenotypically present with asthma-like symptoms.
This article provides an evidence-based approach for clinicians to accurately diagnose asthma in young children and to assess the level of control to guide therapeutic decisions.
The South African Childhood Asthma Working Group (SACAWG) convened in January 2017 with task groups, each headed by a section leader, constituting the editorial committee on assessment of asthma epidemiology, diagnosis, control, treatments, novel treatments and self-management plans. The asthma diagnosis and control task groups reviewed the available scientific literature and assigned evidence according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system, providing recommendations based on current evidence.
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Zanoni BC, et al. BMJ Glob Health 2016;1:e000004. doi:10.1136/bmjgh-2015-000004
Clinical guidelines for the comprehensive care of patients with drug-resistant tuberculosis
Infections by the soil-transmitted helminths (STH), including Ascaris lumbricoides, Trichuris trichiura, Ancylostoma duodenale/Necator americanus (hookworms), and Strongyloides stercoralis, disproportionately affect children around the world. Because of their transmission associated with poor sanita...ry conditions and inadequate hygiene practices, higher burden of disease is seen in children from developing countries from sub-Saharan Africa, Southeast Asia, and Latin America. Approximately 267 million preschool-age children (PSAC) and 568 million school-age children (SAC) worldwide are at risk of STH infection as well as impaired child growth and cognitive development from A. lumbricoides, T. trichiura, and hookworm infections, and death due to severe S. stercoralis infection. Thus, their control is a global health priority.
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Cystic echinococcosis (CE) is a well-known neglected parasitic disease. However, evidence supporting the four current treatment modalities is inadequate, and treatment options remain controversial. The aim of this work is to analyse the available data to answer clinical questions regarding medical t...reatment of CE.
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Troubles Anxieux
Chapitre F.3
Edition en français
Traduction : Alexis Revet
Sous la direction de : Jean-Philippe Raynaud Avec le soutien de la SFPEADA
This study complements the growing amount of research on the psychosocial impact of war on chil-dren in Sierra Leone by examining local perceptions of child mental health, formal and informal care systems, help-seeking behaviour and stigma
Yoder et al. Int J Ment Health Syst (2016) 10:48 DOI 10.11...86/s13033-016-0080-8
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Policy Brief
published: 16 March 2018 doi: 10.3389/fpubh.2018.00069
PLOS Medicine | https://doi.org/10.1371/journal.pmed.1002514 March 1, 2018
Haematologica has published European guidelines for empirical and targeted antibacterial therapy forfebrile neutropenic patients in the era of emerging resistance (ECIL-4). Indeed, collateral damage by broad-spectrum antibiotic therapy includes selection of multidrugresistant pathogens, and incr...eased predisposition to infec-tion by fungi and Clostridium difficile. Antibiotic resistance has become a major public health concern, with fears expressed that we will soon run out of antibiotics.
Haematologica December 2013 98: 1821-1825; doi:10.3324/haematol.2013.091769
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In one of his final essays, statesman and former United Nations secretary general Kofi Annan said, ‘Snakebite is the most important tropical disease you’ve never heard of’. Mr. Annan firmly believed that victims of snakebite envenoming should be recognised and afforded greater efforts at impro...ved prevention, treatment, and rehabilitation. During the last years of his life, he advocated strongly for the World Health Organisation (WHO) and the global community to give greater priority to this disease of poverty and its victims.
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: Development assistance for health (DAH) is one of the most important means for Japan to promote
diplomacy with developing countries and contribute to the international community. This study, for the first time,
estimated the gross disbursement of Japan’s DAH from 2012 to 2016 and clarified its... flows, including source, aid
type, channel, target region, and target health focus area
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Approximately 80% of the 463 million adults worldwide with diabetes live in low-income and middle-income countries (LMICs). A major obstacle to designing evidence-based policies to improve diabetes outcomes in LMICs is the scarce availability of nationally representative data on the current patterns... of treatment coverage. The objectives of this study were to estimate the proportion of adults with diabetes in LMICs who receive coverage of recommended pharmacological and non-pharmacological diabetes treatment; and to describe country-level and individual-level characteristics that are associated with treatment.
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Expert Consensus Validation 2018.
This innovative approach aimed at improving and facilitating the screening, prescribing and monitoring of drug therapy for older patients, is currently being further developed in the area of Clinical Pharmacology at the University of Heidelberg in Mannheim. This ap...proach represents another advance in worldwide research efforts aimed at adding a new dimension to already-existing classification systems and negative listings of potentially inappropriate medications for the elderly.
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In September, 2017, human monkeypox re-emerged in Nigeria, 39 years after the last reported case. We aimed to describe the clinical and epidemiological features of the 2017–18 human monkeypox outbreak in Nigeria.
Investigación original / Original research
Panam Salud Publica. 2016;39(1):38–43.
Gac Méd Caracas 2018;126(1):52-78
Responsibilidad Social Institucional (RSI)
This handbook summarizes the experience of leading practitioners in the field of war surgery and is intended to help military and civilian surgical teams treat people wounded in armed conflicts. It covers first aid, admission of urgent cases and triage, skin grafts, treatment of infections, wounds a...nd burns, plastic surgery and anaesthesiology
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Pessoas privadas de liberdade, por exemplo, detentos em presídios e outros locais de detenção, podem estar mais vulneráveis a doença do coronavírus (COVID-19) quando comparadas à população em geral, devido às condições de confinamento em que vivem com outras pessoas por períodos prolong...ados. Além disso, a experiência mostra que prisões, cadeias e locais semelhantes onde as pessoas estejam reunidas próximas entre si podem agir como fonte de infecção, amplificação e propagação de doenças infecciosas dentro e fora das prisões.
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Guide to bio-safety procedures for dental practices during the COVID-19 pandemic