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Drug discovery for chagas disease: A viewpoint

Kratz J.M. Elsevier (2019) C2
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. It is a significant public health problem, affecting millions of people worldwide. And although it was described 110 years ago, only two old nitroheterocyclic drugs, benznidazole and nifurtimox, are cu ... more
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Duration of antipsychotic treatment in individuals with a first psychotic episode
recommended

World Health Organization WHO (2012) C_WHO
Q3: In individuals with a first psychotic episode with full remission, how long should antipsychotic drug treatment be continued after remission in order to allow for the best outcomes?
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Blueprint for a Public Health and Safety Approach to Drug Policy

Tracy Pugh, Julie Netherland, Ruth Finkelstein The New York Academy of Medicine, Drug Policy Alliance (2013) C2
"Some of the problems with our current drug policies stem from the fact that these policies have been largely bifurcated between two different and often contradictory approaches. One treats drug use ... more
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HIV drug resistance Brief report 2024

World Health Organization WHO (2024) C_WHO
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
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WHO operational handbook on tuberculosis: module 4: treatment: tuberculosis care and support
recommended

World Health Organization WHO (2022) C_WHO
The consolidated guidelines are complemented by an operational handbook which is designed to assist with implementation of the WHO recommendations by Member States, technical partners and others who are involved in the management of patients with DR-TB. The WHO Operational Handbook on Tuberculosis, ... more
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Target Regimen Profiles for TB Treatment

World Health Organization WHO (2016) C_WHO
There is an urgent need for safer, simpler, more efficacious and accessible treatment regimens for all forms of TB. The development of Target Product Profiles for TB treatment regimens (referred to ... more
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The State and Direction of Treatment of Heart Failure with Reduced Ejection Fraction in Papua New Guinea

Kawa, L.B. Journal of Asian Pacific Society of Cardiology (2023) CC
The pharmacological treatment of heart failure has evolved over the last three decades since the demonstration of the effect of angiotensinconverting enzyme inhibitors on major cardiovascular events in patients with heart failure with reduced ejecti ... more
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Emergency Drug Guidelines. Fiji

Ministry of Health, Fiji World Health Organization WHO (2008) C_WHO
The publication of the Second Edition of the Emergency Drug Guidelines represents the culmination of the efforts of the National Drugs and Therapeutics Committee (NDTC) to publish clinical drug guid ... more
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World Drug Report 2022 Booklet 2 Global Overview of Drug Demand and Supply

United Nations Office on Drug and Crime UNODC (2022) C1
Constituting the second part of the World Drug Report 2022, the present booklet contains an overview of the global demand for and supply of drugs. The first chapter of the booklet begins with the latest estimates of the number of people who use dru ... more
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Treatment of Leprosy

Lockwod DN. The International Textbook of Leprosy (2018) CC
This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is a key component of leprosy treatment, as it is v ... more
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Report on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010-2019)

World Health Organization WHO (2020) C_WHO
Antimalarial drug resistance has emerged as a threat to global malaria control efforts, particularly in the Greater Mekong subregion. Drawing on data collected through more than 1000 therapeutic efficacy studies as well as molecular marker studies o ... more
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WHO consolidated guidelines on tuberculosis: module 4: treatment and care

World Health Organization WHO (2025) C_WHO
The Global Programme on Tuberculosis & Lung Health of the World Health Organization (WHO/GTB) is now combining all current recommendations into one overall set of consolidated guidelines on TB. The guidelines contain recommendations pertaining to all areas related to the programmatic management of T ... more
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Guidelines for stopping mass drug administration and verifying elimination of human onchocerciasis: criteria and procedures

World Health Organization World Health Organization WHO (2016) C_WHO
Following the publication of Guidelines on certification of elimination of human onchocerciasis in 2001 by the World Health Organization (WHO), these are the first evidence-based guidelines developed by NTD Department according to the international standards. They provide a set of recommendations th ... more
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World Drug Report 2019 Booklet 5 Drugs and the environment

United Nations Office on Drug and Crime UNODC (2022) C2
The booklet starts with a general overview of how illicit drugs and the environment are linked within the bigger picture of the Sustainable Development Goals, climate change and environmental sustainability. It highlights direct and indirect linkages and gives examples of the significant local and i ... more
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Global status report on alcohol and health and treatment of substance use disorders
recommended

World Health Organisation (WHO) (2024) C_WHO
The Global status report on alcohol and health and treatment of substance use disorders presents a comprehensive overview of alcohol consumption, alcohol-related harm and policy responses as well as treatm ... more
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HIV drug resistance surveillance in countries scaling up pre-exposure prophylaxis

World Health Organization WHO (2020) C_WHO
WHO recommends that pre-exposure prophylaxis (PrEP) be offered as an additional prevention choice for HIV-negative individuals at substantial risk of HIV infection as part of combination prevention approaches. HIV drug resistance has been rarely ... more
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National Guidelines for the Treatment of Malaria - 2019

South African Malaria Elimination Committee (SAMC) National Department of Health South Africa (2019) CC
These guidelines are based on the 3rd Edition of the WHO Guidelines (Published 2015) World Health Organization’s Guidelines for the treatment of malaria. Additional literature surveys have been undertaken. Factors that were considered in the choic ... more