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medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC
commitments in the largest HIV epidemic in the world leads to increased incidence and mortality
and threatens decades of progress in KZN, South Africa. Rest
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oring funding within 12 months
and increasing efficiency of HIV interventions can reestablish KwaZulu Natal province, South
Africa’s trajectory toward EHE goals.
more
WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care cascade, the handbook covers primary prevention, synd
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romic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
more
The decriminalization of drug use and possession for personal use, when implemented effectively, is a critical element in a human rights and public health-based HIV response. The group of countries that have adopted decriminalization models spans all continents. This document brings together differe
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nt approaches to and experiences of decriminalization of drug use and possession for personal use and provides recommendations for countries to ensure an enabling environment for the HIV response.
more
The document is a report by an expert group that presents a framework for improving future pandemic preparedness and emergency response, particularly in the context of India but with relevance to global health systems. It analyzes lessons learned from COVID-19 and past epidemics, identifies key weak
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nesses in areas such as governance, surveillance, data management, research, and coordination, and proposes a comprehensive strategy to address them. The report emphasizes the importance of early detection, strong public health infrastructure, coordinated governance, scientific innovation, and international collaboration. A central idea is the ability to respond effectively within the first 100 days of an outbreak by having systems, resources, and policies already in place. Overall, it aims to strengthen resilience and ensure faster, more efficient responses to future health crises.
more
The document is a practical handbook developed by the European Centre for Disease Prevention and Control (ECDC) that provides guidance on how to design, plan, conduct, and evaluate simulation exercises in public health settings. Its main purpose is to help organisations improve their preparedness an
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d response to communicable disease outbreaks by using structured exercises as a training and evaluation tool. The handbook explains different types of exercises, outlines the steps involved in organising them, and highlights the importance of clear objectives, coordination, and evaluation. Overall, it aims to strengthen emergency preparedness by enabling organisations to identify weaknesses, improve collaboration, and enhance their ability to respond effectively to public health crises.
more
The document is a practical toolkit that provides guidance for healthcare facilities on how to prepare for emergencies, including pandemics and other disasters. It explains how to conduct risk assessments using an all-hazards approach, helping facilities identify potential threats such as natural di
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sasters, technical failures, and disease outbreaks. The text outlines how to develop emergency preparedness and pandemic plans, including key elements like communication, staffing, resource management, and coordination with local, state, and federal authorities. It also describes the four phases of emergency management—mitigation, preparedness, response, and recovery—and emphasizes continuous evaluation and improvement. Overall, the document aims to help healthcare organizations ensure continuity of care and protect patients and staff during emergencies.
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Successful retention and re-engagement in HIV care depends largely on the ability of the provider to involve and motivate patients to attend ongoing care
Artificial intelligence for tuberculosis control: a scoping review of applications in public health
Menon, S.; and K. Ghislein Kuro
(2025)
J Glob Health. 2025;15:04192. This scoping review highlights the potential of AI-driven predictions in national TB programmes to enhance diagnostics, track trends, and strengthen public health surveillance. While promising for reducing transmission and support-
ing TB care in low-resource settings,
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these models require large-scale validation to ensure real-world applicability, especially for high-risk groups
more
BMC Public Health (2025) 25:3774 https://doi.org/10.1186/s12889-025-24555-6. The study results provide useful insights on how climate change influences malaria in African countries, and reiterates the need for a greater engagement of policymakers and social partners, in intensifying the action neede
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d to fight the transmission of malaria in Sub-Sahara Africa
more
Para sobrevivir y prosperar, los niños y adolescentes necesitan una buena salud, una nutrición adecuada, un entorno limpio, seguro y de apoyo, oportunidades para el aprendizaje temprano y la educación, relaciones sensibles y de conexión, así como oportunidades para la autonomía personal y la a
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utorrealización. Para promover su salud y bienestar, requieren el acompañamiento de padres, familias, comunidades, instituciones cercanas y un entorno propicio. También necesitan controles rutinarios y consultas regulares con proveedores de salud que garanticen su crecimiento, desarrollo y bienestar durante las dos primeras décadas de vida, y que apoyen y orienten a los padres en el cuidado que brindan tanto a sus hijos como a sí mismos.
more
This issue brief aims to provide a comprehensive overview of key publications, guidelines, and practical materials on malaria prevention, diagnosis, and treatment. The selected documents reflect current evidence and field-based experiences, supporting healthcare professionals, researchers, and publ
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ic health authorities in their efforts to control and eliminate malaria.
more
The GHEC framework is designed to provide guiding principles for standardizing health emergency workforce structures to strengthen the capacity of countries in responding to health emergencies, and to enhance collaboration between countries by better connecting regional and global surge response mec
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hanisms, facilitating information exchange, and improving access to expertise and human response capacity at times of need.
This is the first version of the GHEC framework and is intended to be updated as experience is gained with its implementation and adaptation.
more
The Global hepatitis report 2026 provides the most comprehensive and up-to-date assessment of the global burden of hepatitis B (HBV) and hepatitis C (HCV), which together account for more than 95% of deaths related to viral hepatitis. Despite being preventable and treatable, viral hepatitis remains
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one of the leading infectious disease killers worldwide.
The report also highlights the progress in response efforts at global, regional and country levels, in the context of global commitments, strategies and targets.
more
Preparedness and response to bacterial meningitis outbreaks: toolkit for frontline healthcare workers
recommended
New
Designed as a suite of job aids on acute bacterial meningitis, this document serves as a resource for frontline healthcare professionals globally, including in settings where the risk of outbreaks and excess mortality is highest. With a primary focus on acute bacterial meningitis in children aged ov
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er 1 month, adolescents and adults, the toolkit provides clinical guidance on the causative pathogens, clinical manifestations, diagnostic investigations, antibiotic therapy, adjunctive treatment, supportive care, post-exposure antibiotic prophylaxis, and infection prevention and control in healthcare settings.
more
As countries presented their epidemiological and programmatic situations, and WHO summarized the global status of HAT, the central message was one of satisfaction with the remarkable progress towards elimination. A historically low number of cases was reported, despite maintaining high levels of act
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ive and passive screening in all accessible at-risk areas. In addition, 10 countries have been officially validated for the elimination of HAT as a public health problem.
Time was also devoted to reviewing progress and challenges in the areas of diagnostics, therapeutics and vector control interventions.
more
This guidance addresses one type of generative AI, large multi-modal models (LMMs), which can accept one or more type of data input and generate diverse outputs that are not limited to the type of data fed into the algorithm. It has been predicted that LMMs will have wide use and application in heal
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th care, scientific research, public health and drug development. LMMs are also known as “general-purpose foundation models”, although it is not yet proven whether LMMs can accomplish a wide range of tasks and purposes.
more
TArtificial intelligence (AI) is transforming health systems, reshaping how care is planned, delivered and governed. This report presents the first assessment of AI integration into health systems across the whole of the WHO European Region, based on findings from the 2024–2025 survey on AI for he
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alth care. It examines national strategies, governance models, legal and ethical frameworks, workforce readiness, data governance, stakeholder engagement, private sector roles and the uptake of AI applications. Drawing on insights from 50 Member States, the report explores how countries are navigating opportunities and challenges, highlighting emerging trends, gaps and practices to guide policy-makers towards coherent, ethical and people-centred approaches to AI in health care.
more
A Global Access Framework for Country-Led.
ResponsesThis 2030 Prevention access framework focuses on one of those top-line targets, which covers primary prevention and requires that 90% of people in need of HIV prevention are using effective prevention options by 2030. This target is disaggregated
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into 15 second-line prevention targets for specific populations and programmes.
The 2030 Prevention Access Framework presents in greater detail the milestones and actions for achieving these targets––all of which are grounded in the three priorities of the Global AIDS Strategy: country-led, resilient and sustainable HIV responses; people-focused services, and community leadership
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The Gender Assessment Tool for National HIV Responses (Gender Assessment Tool) is intended to assist countries in assessing their HIV epidemic, context and response through an intersectional gender lens, with the aim of strengthening gender-transformative, equitable and rights-based HIV responses. T
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he 2025 tool places greater emphasis on cost-effectiveness, alignment with national plans, integration and sustainability. Together with a new costing tool and monitoring and evaluation plan template, it is designed to inform the development of country investment cases, funding requests to the Global Fund to Fight AIDS, Tuberculosis and Malaria, and other key national opportunities.
more
This report developed by UNAIDS and the United for Global Mental Health reviews and maps Global Fund investments in priority HIV and TB comorbidities in Grant Cycle 7 (GC7), including key non-communicable diseases (NCDs), cervical, anorectal and other cancers, and mental health and substance use co
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nditions. It highlights how countries prioritize and are integrating health services and other interventions with HIV and TB programmes to advance person-centered approaches and to sustain HIV and TB responses. Analyzing approved grants from 103 countries, the report finds strong demand for integrated approaches, with 97% of countries prioritizing at least one comorbidity.
more