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6
Operational requirements for implementing WHO recommendations in digital systems. 2nd edition.
To ensure that countries can effectively benefit from digital health investments, “digital adaptation kits” (DAKs) are designed to facilitate the accurate reflection of WHO’s clinical, public health
...
and data use guidelines in the digital systems that countries are adopting. DAKs are operational, software-neutral, standardized documentations that distil clinical, public health and data use guidance into a format that can be transparently incorporated into digital systems.
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Background Note: Briefing to the Executive Board, First Regular Session 2025
Preprint VeriXiv 2025, 2:226 Last updated: 20 OCT 2025
Progress on the sustainable development goals.
Guidelines for the Prevention and Treatment of Opportunistic Infections in Children With and Exposed to HIV
recommended
Full Guidelines
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Pathogens 2022, 11, 33. https://doi.org/10.3390/pathogens11010033
This comprehensive analysis outlines the recommended mental health services in HIV
care, delivery modalities, required resources, guideline integration, special population
considerations, and implementation strategies with real-world examples
The paper “Artificial Intelligence for Public Health Surveillance in Africa: Applications and Opportunities” examines how artificial intelligence (AI) can improve public health systems across Africa, particularly in low-resource settings. It explores how machine learning and other AI techniques
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are being used for disease detection, outbreak prediction, real-time surveillance, and health resource management.
The authors focus on major public health challenges such as HIV, cholera, Ebola, measles, tuberculosis, malaria, COVID-19, and mental health. Through numerous case studies, the paper shows that AI can enhance the accuracy and speed of disease detection, predict outbreaks more effectively than traditional methods, support vaccination strategies, and optimize healthcare resource allocation. At the same time, it discusses important barriers to implementation, including limited data quality, infrastructure constraints, ethical concerns, and shortages of technical expertise.
Overall, the paper highlights AI’s strong potential to strengthen disease surveillance and health outcomes in Africa while emphasizing the need for careful integration, improved data systems, and supportive policy frameworks.
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The document “Communicable Disease Surveillance and Response Systems: A Guide to Planning” is a World Health Organization (WHO) guide designed to help countries develop and strengthen national surveillance and response systems for communicable diseases . It explains why surveillance is essential
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for early detection of outbreaks, informed decision-making, and effective public health action, especially in the context of the revised International Health Regulations (2005).
The guide provides a structured approach to strategic and operational planning. It outlines how countries should assess their existing systems, define a vision and goals, identify expected key result areas (EKRAs), prioritize activities, set realistic targets, allocate resources, and monitor progress. It also includes practical tools such as templates, worksheets, and examples to support ministries of health in organizing planning workshops and developing multi-year strategic plans and annual operational plans. Overall, the document serves as a practical framework to improve preparedness, early warning, and response to public health emergencies.
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Early Warning and Response to Outbreaks and other Public Health Events: A Guide provides practical guidance for strengthening early warning functions within existing public health surveillance systems in WHO’s South-East Asia Region. The document explains how countries can detect, verify, and resp
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ond rapidly to outbreaks and other unusual public health events in line with the International Health Regulations (2005). It describes the five key steps of an Early Warning and Response (EWAR) system—information collection, signal detection, event verification, response, and communication—and outlines how to set alert thresholds, identify signals, and ensure timely reporting. The guide also includes recommendations for monitoring and evaluating system performance to improve timeliness, sensitivity, and overall effectiveness in preventing and controlling public health threats.
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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
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ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
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World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.
The Health Emergency and Disaster Risk Management
Chan E.Y.Y., Huang Z., Hung K.K.C. et al
United Nations Office for Disaster Risk Reduction UNDRR
(2022)
CC
An emerging framework for achieving synergies among the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. This paper discusses the potential of the Health Emergency and Disaster Risk Management (Health-EDRM) Framework in promoting syne
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rgies in pursing risk- resilient sustainable development pathways via conceptual analysis of the key roles of health and Health-EDRM in the major international risk-resilient and sustainable development agendas of the Sendai Framework, the 2030 Agenda for Sustainable Development, the New Urban Agenda and the Paris Agreement. It first analyses the Health-EDRM Framework, which is a comprehensive, systematic, cross-sectoral, and interdisciplinary endeavour of the World Health Organization and its health and non- health partners. The four key international risk-resilient and sustainable development agendas are then analysed in detail to explore how they can be interlinked and synergised under the Health-EDRM Framework.
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Guide to revision of national pandemic influenza preparedness plans - Lessons learned from the 2009 A(H1N1) pandemic
Brown C., Ciotti M., Hegermann-Lindencrone M., et al
European Centre for Disease Prevention and Control (ECDC), WHO Regional Office for Europe
(2017)
C_WHO
The document “Guide to revision of national pandemic influenza preparedness plans – Lessons learned from the 2009 A(H1N1) pandemic” provides guidance for countries on how to improve and update their national pandemic preparedness plans. It is based on lessons learned from the 2009 influenza pa
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ndemic and aims to help governments strengthen their readiness for future pandemics. The report outlines key components of effective pandemic planning, including risk assessment, coordination between sectors, communication strategies, healthcare system preparedness, vaccination and antiviral strategies, and business continuity planning. It also emphasizes the importance of international cooperation and flexible planning that can adapt to different pandemic scenarios. Overall, the guide serves as a framework to support countries in developing stronger, more coordinated responses to future influenza pandemics.
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medRxiv preprint;https://doi.org/10.64898/2026.02.18.26346597. This model application demonstrates that the sudden cessation of USAID and CDC
commitments in the largest HIV epidemic in the world leads to increased incidence and mortality
and threatens decades of progress in KZN, South Africa. Rest
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oring funding within 12 months
and increasing efficiency of HIV interventions can reestablish KwaZulu Natal province, South
Africa’s trajectory toward EHE goals.
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This document consolidates, for the first time, WHO recommendations on the prevention, testing, treatment and monitoring of hepatitis B and C, and includes testing strategies for hepatitis D. Drawing on a decade of evidence-based guidance issued between 2015 and 2025, it provides a single, practical
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handbook to support global progress toward eliminating viral hepatitis by 2030.
The document also highlights simplified service delivery models that promote decentralization, integration with primary care and related programmes such as HIV and tuberculosis, as well as task sharing and differentiated care to expand access and improve efficiency. It further underscores the need for robust data and monitoring systems to support effective programme implementation.
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The publication "Aligning national drought plans with global and national policy frameworks" provides governments and practitioners with practical guidance on how to align national drought plans (NDPs) with existing policy, legal and institutional frameworks to enable effective implementation. It po
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sitions policy alignment as a core requirement for moving from reactive drought response to proactive, risk-based drought management, in line with national development priorities and international commitments.The report presents two complementary methodologies that support alignment across both the planning and implementation phases of NDPs. A multicriteria assessment framework is used to review the quality, readiness and internal coherence of drought plans, while a policy alignment approach examines how drought is recognized and addressed across sectoral policies, institutional mandates and coordination mechanisms.
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The document provides guidance from the CDC on conducting an Operational Readiness Review (ORR) within the Public Health Emergency Preparedness (PHEP) cooperative agreement. It outlines the purpose, structure, and evaluation criteria used to assess whether public health systems are prepared to respo
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nd effectively to emergencies. The guidance describes required capabilities, review processes, and documentation expectations, helping jurisdictions demonstrate their readiness and identify areas for improvement in emergency preparedness and response.
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The document provides practical guidelines for conducting a national disaster risk assessment, developed by the United Nations Office for Disaster Risk Reduction. It emphasizes the importance of understanding disaster risk as a foundation for effective disaster risk management and sustainable develo
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pment. The guidelines outline a structured process that includes preparing and scoping the assessment, conducting risk analysis, and using the results to inform policy and decision-making. They promote a comprehensive, multi-hazard approach that considers vulnerabilities, exposure, and capacities, while encouraging collaboration among governments, experts, and stakeholders. Overall, the document aims to help countries build stronger systems for assessing and managing risks, thereby enhancing resilience and reducing the impacts of disasters.
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