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The number of COVID-19 cases is on the rise again, with South Africa nearing half of all confirmed cases in the WHO African Region. Threats of new variants loom and low vaccination coverage raises questions on the future of the response to COVID-19. Prevention remains the key strategy in most sub-Sa ... more
Journal of Cancer Education https://doi.org/10.1007/s13187-020-01935-7
Drugs & Therapy Perspectives vol.36 (2020) 6
A toolkit for pharmacists. Emerging data show that medication errors and adverse events cause significant harm to patients’ health and well-being. It is estimated that the burden of adverse events due to medicines is now comparable to that of widespread diseases, such as malaria or tuberculosis ... more
This guidance provides interim guidance for the integration of SARS-CoV-2 and influenza virologic and genomic surveillance, from sentinel site case enrolment and sampling to the eventual sharing of the virus sequence data, a process known as end-to-end surveillance. This guidance builds on experienc ... more
Guidance for Orphans and Vulnerable Children Programs
Kenya Quality Model for Health - Level 2 Facilities
Kenya Quality Model for Health - Health Facilities
Kenya Quality Model for Health - Hospitals
South Africa has a long history of community health workers (CHWs). It has been a journey that has required balancing constrained resources and competing priorities. CHWs form a bridge between communities and healthcare service provision within health facilities and act as the cornerstone of South A ... more
Community health workers (CHWs) enable marginalised communities, often experiencing structural poverty, to access healthcare. Trust, important in all patient–provider relationships, is difficult to build in such communities, particularly when stigma associated with HIV/AIDS, tuberculosis and now ... more
Information note. In 2021, preliminary results of observational studies from the Community Access to Rectal Artesunate for Malaria (CARAMAL) project did not confirm the mortality impact observed in the controlled trial in 2009. Consequently, in January 2022, WHO released an information note on recta ... more
Update, 2023. En 2021, les résultats préliminaires des études d’observation du projet CARAMAL (Community Access to Rectal Artesunate for Malaria) n’ont pas confirmé l’impact sur la mortalité observé dans l’essai contrôlé de 2009. Par conséquent, en janvier 2022, l’OMS a publié un ... more
Good Manufacturing Practice (GMP) describes a set of principles and procedures that, when followed, ensure that medicines and related substances are of high quality, safety and efficacy. SAHPRA is a participating authority of the Pharmaceutical Inspection Cooperation Scheme (jointly known as PIC/S) ... more
Updated Guidelines

Shorter treatment for children with minimal TB

SHINE Medical Research Council Clinical Trials Unit (MRC CTU) at UCL (2022) CC
The results of the SHINE trial have been published in the NEJM today. SHINE looked at whether treatment for children with minimal TB could be reduced from 6 months to 4 months. It found that the four month treatment was as good as the standard six months treatment for children with minimal TB
Operation update 01/04/2022
N Engl J Med 2022; 386:911-922, DOI: 10.1056/NEJMoa2104535 Four months of antituberculosis treatment was noninferior to 6 months of treatment in children with drug-susceptible, nonsevere, smear-negative tuberculosis (SHINE Study)
Information note
The Lancet Global Health Volume 9, ISSUE 3, e361-e365, March 01, 2021 The public health community has tried for decades to show, through evidence-based research, that safe water, sanitation, and hygiene (WASH) and clean cooking fuels that reduce household air pollution are essential to safeguard he ... more