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Evidence summary: systematic review of oral fexinidazole as first line treatment for rhodesiense Human African Trypanosomiasis

World Health Organization WHO (2024) C_WHO
Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
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Target product profile for a gambiense human African trypanosomiasis individual test to assess infection in low prevalence settings

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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Trypanosomiase humaine africaine/ Human African Trypanosomiasis

World Health Organization WHO, MSF (2002) C_WHO
UN GUIDE POUR L’APPROVISIONNEMENTEN MÉDICAMENTS/ A guide for drug supply Bochure in English and French
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Oral pre-exposure prophylaxis - Putting a new choice in context

UNAIDS (Joint United Nations Programme on HIVAIDS); World Health Organization (WHO); Global Advocacy for HIV Prevention (AVAC) UNAIDS (Joint United Nations Programme on HIVAIDS); World Health Organization (WHO); Global Advocacy for HIV Prevention (AVAC) (2015) C2
Reference
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Target product profile for a gambiense human African trypanosomiasis high-throughput test for verification of elimination

World Health Organization WHO (2022) C_WHO
HAT diagnosis relies on laboratory techniques because clinical signs and symptoms are unspecific. Serodiagnostic tests exist only for Tbg and are based on the detection of specific antibodies, thus they are not confirmatory of infection. With the current low disease prevalence, the positive predicti... more
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New WHO guidelines for treating rhodesiense human African trypanosomiasis: expanded indications for fexinidazole and pentamidine
recommended

Lindner A. K.; V. Lejon, M.P. Barrett, et al. (2025) CC
The Lancet Infectious Disease Volume 25, Issue 2e77-e85February 2025
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Diagnostic target product profiles for trachoma surveillance
recommended

World Health Organization WHO (2024) C_WHO
Trachoma is the leading infectious cause of blindness worldwide. In April 2023, it was a public health problem in approximately 40 countries, with an estimated 116 million people at risk and 1.5 million people affected by the late blinding stage of the disease (1). About 84% of those at risk of tr... more
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Disorders due to substance use

World Health Organization (2019) C_WHO
Accessed: 21.03.2019
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Practical Approaches to Implementing WHO Guidance for Neglected Tropical Disease (NTD) Programs in the Context of COVID-19: Trachoma Surveys

U.S. Agency for International Development and its Act to End NTDs (2021) CC
Version 1: March 9, 2021. A living document
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Vision and eye screening implementation handbook

World Health Organization WHO (2024) C_WHO
The WHO Vision and eye screening implementation handbook (VESIH) offers a step-by-step guidance for conducting vision and eye screenings in community and primary care settings. The evidence-based interventions are drawn from the WHO Package of eye care interventions and developed with a focus on del... more
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Zambia. Demographic and Health Survey 2018

Central Statistical Office (CSO) [Zambia], Ministry of Health (MOH) [Zambia], and ICF (2020) C1
Final Report
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Sierra Leone National AIDS Response Progress Report 2015

Ministry of Health and Sanitation, Sierra Leone; UNAIDS (2015) C_WHO
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Toolkit 2.0. Expanding and simplifying treatment for pregnant women living with HIV: Managing the transition to Option B/B+

World Health Organization (WHO), Inter-Agency Task Team (IATT), UNICEF (2013) C_WHO
The toolkit is a collection of assessment tools and checklists that describe the key considerations to be taken into account when transitioning to Option B/B+. The toolkit provides a roadmap to support the planning and implementation of Option B/B+, and to help countries scale up more effective inte... more
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Philippines: National Demographic and Health Survey 2003

National Statistics Office Manila, Philippines; ORC Macro International USAID (2004) C1