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Laboratory biosafety guidance related to coronavirus disease (COVID-19): Interim guidance, 28 January 2021
recommended
The latest update (28 January 2021) includes the following addition and revision:
biosafety aspects for working with antigen-detecting rapid diagnostic test;
handling new variants of SARS-CoV-2 in the laboratory;
updated assay decon
...
tamination before disposal;
personal protective equipment (PPE) for specimen collection;
addressing chemical hazards and their safe disposal; and
the fourth edition of the WHO Laboratory Biosafety Manual (LBM4) is now available and the terminology in this guidance was aligned with the LBM4.
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This guidance synthesizes current evidence on dengue laboratory testing and diagnostics and provides practical recommendations for laboratories, clinicians, public health officials, and programme managers involved in dengue diagnosis, surveillance,
...
and control, in the context of the global emergency. It includes a diagnostic algorithm for suspected cases, outlining appropriate testing methods based on days post symptom onset.
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GPHF-Minilab: Manuals
recommended
GPHF Minilab manuals on basic dye and thin layer chromatographic testing. The newest version of the manual (Volume I + II) from 2008 is available in three languages: English, French, Spanish. Combining the main manual with the supplements issued each year between 2010 and 2015, label claims on drug
...
identity and content can now be verified for 75 active ingredients and their fixed-dose combination products using simple, rapid and affordable thin layer chromatographic tests. Please note: Only the demo versions are online available!! The complete manuals are only available after purchasing the Minilab!
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Method for molecular diagnostics, enabling limitless testing possibilities.
High precision & speed: Mammoth uses CRISPR-based systems (DETECTR platform) to detect specific DNA or RNA sequences from pathogens (e.g. COVID-19, Zika, dengue). Versatility: The platform can, in theory, be programmed to d
...
etect any pathogen. Point-of-need deployment: The tests are designed to operate outside specialised high-security laboratories, for example in small clinics or on-site (point-of-care). Robustness: The tests function under a wide range of conditions, which is important for environments with limited infrastructure
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Interim Recommendation published 19 September 2014. These recommendations reflect current understanding of Ebola virus disease (EVD) and are intended for national laboratory staff performing diagnostic testing to detect Ebola virus.
2nd edition
"Achieving, maintaining and improving accuracy, timeliness and reliability are major challenges for health laboratories. Countries worldwide committed themselves to build national capacities for the detection of, and response to, public health events of international concern when they decided to eng
...
age in the International Health Regulations implementation process. Only sound management of quality in health laboratories will enable countries to produce test results that the international community will trust in cases of international emergency. This handbook is intended to provide a comprehensive reference on Laboratory Quality Management System for all stakeholders in health laboratory processes, from management, to administration, to bench-work laboratorians. This handbook covers topics that are essential for quality management of a public health or clinical laboratory. They are based on both ISO 15189 and CLSI GP26-A3 documents"--Page 7.
more
This document assembles these best practices and provides a resource for the proper management of equipment in the laboratory to ensure accurate, reliable and timely testing, and maintain a high level of l
...
aboratory performance. Improved equipment management also lowers repair costs, lengthens instrument life, reduces interruption of services due to breakdowns and failures, and enables laboratory accreditation and the achievement of high-quality and accessible laboratory services at all levels of healthcare service delivery.
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The purpose of this document is to provide interim guidance to laboratories and stakeholders involved in laboratory testing of patients who meet the definition of suspected case of pneumonia associated with a novel coronavirus identified in Wuhan, C
...
hina.
19 March 2020
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8 July 2020
WHO has developed this manual in order to strengthen the laboratory diagnosis and virological surveillance of influenza infection.
This document provides interim guidance to countries on testing considerations and strategies for suspect cases of severe acute hepatitis of unknown aetiology in children. It is primarily intended for clinical, programmatic, laboratory and diagnosti
...
c stakeholders across Member States and national public health authorities involved in the identification and investigation of cases of severe acute hepatitis in children.
This document is part of a package of guidance for this event, which includes suggested minimum reporting variables and a clinical Case Report Form support Member States with case investigation and reporting.
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Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory
...
-based surveillance, production of biologicals and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
more
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory
...
-based surveillance, production of biologicals and management of this infectious disease are critical. Given its mandate to improve human health and control disease among its Member States, WHO has led the production of this fifth edition of Laboratory techniques in rabies.
more
On May 17, 2026, the World Health Organization (WHO) declared the Ebola outbreak in the Democratic Republic of Congo (DRC) and Uganda as a Public Health Emergency of International Concern (PHEIC). This was followed by Africa Centres for Disease Control and Prevention (Africa CDC) declaration on 18 M
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ay 2026 as a Public Health Emergency of Continental Security (PHECS) signalling the seriousness of the situation and calling for immediate actions. Unlike previous outbreaks of Ebola Virus Disease (EVD) caused by zaire strain for which validated countermeasures have been available, there is currently lack of vaccines and therapeutics for the Bundibugyo ebolavirus strain that is driving the current outbreak. In addition, only a limited number of clinical diagnostics tests have been approved or validated for use. These gaps in effective medical countermeasures are constraining the outbreak response efforts.
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