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Developmental roadmap for antimicrobial susceptibility testing systems

Belkum, A.van, T. T. Bachmann, G. Lüdke, et al. (2019) CC

Nature Reviews Microbiology Vol. 17 (2019)pp.51-62 Antimicrobial susceptibility testing (AST) technologies help to accelerate the initiation of targeted antimicrobial therapy for patients with infections and could potentially extend the lifespan ... more

Pocketbook for management of Diabetes in Childhood and Adolescence in under-resourced Countries

Ogle, G.; Middlehurst, A.; Silink, M.; Hanas, R. International Diabetes Federation (2017) CC2

The document "Pocketbook for Management of Diabetes in Childhood and Adolescence in Under-Resourced Countries" (2nd Edition) provides practical guidelines for managing diabetes in children and adolescents, particularly in resource-limited settings. It covers key topics like diagnosing and treating d ... more

Addressing comorbidity between mental disorders and major noncommunicable diseases

World Health Organization WHO; Regional Office for Europe (2017) C_WHO

Reduced healthy life expectancy due to the high burden of both mental ill health and noncommunicable diseases (NCDs) is a major public health concern in the European Region. The links between mental disorders and major NCDs are well established. In clinical practice, however, mental disorders in pa ... more

Management of febrile seizures

World Health Organization WHO (2012) C_WHO

Q3: Can febrile seizures (simple or complex) be managed at first or second level care by non-specialist health care providers in low and middle income country settings? What is the role of diagnostic tests in the management of febrile seizures by non-specialists in low and middle income settings? Fo ... more

Antidepressant medication in comparison with psychological treatment for moderate to severe depressive disorder
recommended

World Health Organization WHO (2015) C_WHO

Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm ... more

Prevention and Control of Non-Communicable Diseases in Zambia: The Case for Investment

Ministry of Health, Zambia (2020) CC

The Government of the Republic of Zambia has placed priority on ensuring that Zambians are healthy and productive as a catalyst to the attainment of socioeconomic development . The Vision 2030 aims to transform Zambia into a prosperous middle-income country as articulated also in the 7th National De ... more

Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for ... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

WHO list of priority medical devices for cancer management

World Health Organization WHO (2017) C_WHO

This publication is based on the list of clinical interventions selected from clinical guidelines on prevention, screening, diagnosis, treatment, palliative care, monitoring and end of life care. This publication addresses medical devices for six types of cancer: breast, cervical, colorectal, leukem ... more

WHO manual for HIV drug resistance testing using dried blood spot specimens

World Health Organization WHO (2020) C_WHO

HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middle-income countries, since preparing and storing it ... more

Quit tobacco

World Health Organization WHO (2019) C_WHO

The document provides inforation on tobacco use (health effects, quitting, benefits of quitting, e-cigarettes etc.) in a descriptive way.

Communicable and non-communicable diseases in Africa in 2021/22

World Health Organization Africa Region; WHO Africa World Health Organization Africa Region; WHO Africa (2023) C_WHO

This report is one of the first major products of the newly established Precision Public Health Metrics unit of the UCN cluster of the WHO Regional Office for Africa. The report presents national trends in communicable and non-communicable disease burden and control in the WHO African region. It tra ... more

Guidelines for the clinical management of severe illness from influenza virus infections

World Health Organization WHO (2022) C_WHO

The purpose of this document is to guide clinicians in the care of patients with or at risk of severe illness from influenza virus infection, including those caused by seasonal influenza viruses, pandemic influenza viruses and zoonotic (novel influenza A) viruses.

Pocket book of hospital care for children
recommended

World Health Organization (WHO) (2013) C_WHO

Guidelines for the Management of common childhood Illness. 2nd edition These guidelines focus on the management of the major causes of childhood mortality in most developing countries, such as newborn problems, pneumonia, diarrhoea, malaria, meningitis, septicaemia, measles and related conditions, ... more

Ending Preventable Child Deaths from Pneumonia and Diarrhoea by 2025

World Health Organization; UNICEF (2013) C_WHO

The integrated Global Action Plan for Pneumonia and Diarrhoea (GAPPD)

Оксигенотерапия у детей

World Health Organization WHO (2020) C2

Это руководство является частью серии, созданной для повышения качества лечения тяжело больных детей в медицинских учреждениях. Оно направлено на увеличение дост ... more

National Guidelines of ART

National AIDS STD Program, Directorate General of Health Services, Ministry of He alth and Family Welfare (2011) C1

Guidelines for the Clinical Management of TB and HIV Co-infection in Ghana

National HIVAIDS (2010) C1

The Wise List 2015

Stockholm Drug and Therapeutics Committee (2015) C_WHO

with recommended essential medicines for common diseases in patients in Stockholm County Council (Healthcare Region), Sweden

Standard treatment guidelines acute sinusitis (India)

Ministry of Health & Family Welfare, India (2017) C1