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21 January 2022 The overall threat posed by Omicron largely depends on four key questions: (i) how transmissible the variant is; (ii) how well vaccines and prior infection protect against infection, transmission, clinical disease and death; (iii) how virulent the variant is compared to other varian... more
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Antibiotic resistant bacteria are spreading at an alarming rate and some bacterial infections may once again be untreatable. Antibiotic resistance (ABR), conservatively calculated, causes more than 500 000 deaths every year. This number is projected to rise dramatically if radical actions are not ta... more
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Interim recommendations for heterologous COVID-19 vaccine schedules

World Health Organization WHO (2021) C_WHO
Overview 16 Dec 2021. This interim guidance pertains to heterologous primary and heterologous boosting schedules of Covid-19 vaccines. It focuses on heterologous schedules combining multiple vaccine platforms (e.g. a vectored vaccine followed by an mRNA vaccine).
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Vitamin Deficiency and Tuberculosis: Need for Urgent Clinical Trial for Managment of Tuberculosis

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Addressing the antibiotic resistance threat– the role of water, sanitation and hygiene

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Antibiotic resistant bacteria are spreading at an alarming rate and some bacterial infections may once again be untreatable. Antibiotic resistance (ABR), conservatively calculated, causes more than 500 000 deaths every year. This number is projected to rise dramatically if radical actions are not ta... more
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Global Plan to End TB 2023-2030

Stop TB Partnership; UNOPS; END TB (2022) C1
This Global Plan builds on the previous edition, which laid out priority actions for 2018-2022, informed by global commitments member states endorsed at the 2018 United Nations High-Level Meeting (UNHLM) on TB. The resource needs estimates from this Global Plan include resources needed for implement... more
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Control and elimination of Schistosoma mansoni infection in adult individuals on Ukerewe island, northwestern Tanzania: baseline results before implementation of intervention measures

Mazigo, H.D.; Chiombola, C.E., S. Mugassa, et al. (2024) CC
BMC Infectious Diseases (2024) 24:1102 Communities living along the shoreline and on the islands of Lake Victoria in northwestern Tanzania remain endemic for schistosomiasis and suffer from the life-threatening morbidities associated with the disease.
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Profiles of Peripheral CD4+T Cells Count during Antiretroviral Treatment in Senegalese Adults Infected by HIV: Impact of Therapeutic Associations

Niang M. S., R. Derwiche, B. Mbengue Journal of Immunology, Infection & Inflammatory Diseases (2017) CC
Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets especially CD4+ T cells, leading to deficiency of ... more
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Oral pre-exposure prophylaxis - Putting a new choice in context

UNAIDS (Joint United Nations Programme on HIVAIDS); World Health Organization (WHO); Global Advocacy for HIV Prevention (AVAC) UNAIDS (Joint United Nations Programme on HIVAIDS); World Health Organization (WHO); Global Advocacy for HIV Prevention (AVAC) (2015) C2
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