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2
The WHO Guide on Oral Cholera Vaccines in Mass Immunization Campaigns provides guidance on the planning and implementation of oral cholera vaccine (OCV) campaigns. It covers key aspects such as when and where to use OCVs, vaccine specifications, and recommendations for use in endemic areas, outbreak
...
settings, and complex emergencies. The document outlines steps for macro- and micro-planning, logistics, budgeting, human resource allocation, and risk communication. It also highlights challenges, including cold chain management, vaccine supply, and community engagement, ensuring that vaccination campaigns are efficient and effective in reducing cholera outbreaks.
more
The technical note from the Global Task Force on Cholera Control (GTFCC) examines the risks and benefits of vaccinating pregnant women with WHO-prequalified oral cholera vaccines (OCVs) during mass vaccination campaigns. It highlights that three WHO-approved vaccines (Dukoral®, Shanchol™, and Euv
...
ichol®) offer sustained protection and a strong safety profile.
While these vaccines are not explicitly contraindicated for pregnant women, there is limited clinical data on their use during pregnancy. However, studies indicate that pregnant women with cholera face higher risks of fetal loss, stillbirth, and complications, especially if they experience severe dehydration. Some evidence suggests that vaccination can reduce cholera incidence in pregnant women and indirectly protect infants.
Although no controlled trials have focused on pregnant women, retrospective studies in Guinea and Zanzibar showed no significant increase in adverse pregnancy outcomes after OCV administration. The GTFCC concludes that the benefits of vaccination outweigh the risks, particularly in high-risk areas, and recommends including pregnant women in cholera vaccination campaigns while continuing to monitor safety data.
more
The technical note by the Global Task Force on Cholera Control (GTFCC) discusses the use of Oral Cholera Vaccines (OCVs) for international workers and travelers in cholera-affected areas. It reviews the effectiveness of WHO-prequalified vaccines (Dukoral®, Shanchol™, and Euvichol®), emphasizing
...
their role in preventing infection and reducing transmission risks.
The document highlights concerns about travelers contracting cholera in endemic regions and potentially spreading the disease upon returning home. While the overall risk is considered low, certain groups, such as humanitarian workers and travelers to high-risk areas like South Asia, face a higher exposure.
Recommendations include vaccination for emergency and relief workers who may come into direct contact with cholera patients or contaminated environments. However, routine vaccination for general travelers is not widely recommended. The note also calls for better surveillance and studies to assess the potential of vaccines in preventing international transmission.
more
The Interim Guidance on Cholera Rapid Diagnostic Tests (RDTs) by the Global Task Force on Cholera Control (GTFCC) provides recommendations for using RDTs to detect cholera in areas with limited laboratory capacity. It highlights the advantages of RDTs, such as rapid detection (within 30 minutes), ea
...
se of use by non-laboratory personnel, and their role in early outbreak identification and surveillance. However, it emphasizes that RDTs should not replace culture or PCR testing, as they vary in sensitivity (58-100%) and specificity (60-100%). The document advises on proper test selection, storage, training, and integration into national surveillance systems to enhance cholera response efforts.
more
The objective of this guidance document is to support the public health professionals
in implementing effective surveillance of cholera in at-risk, endemic and epidemic
areas. This document has been developed by the Surveillance Working Group of t
...
he
Global Task Force for Cholera Control (GTFCC) at the World Health Organization based
on the existing documents, guidelines, tools and articles related to surveillance of
cholera disease, as well as technical discussions with experts held during GTFCC
meetings.
more
The WHO Cholera Rapid Diagnostic Test (RDT) Target Product Profile outlines the key requirements for developing improved cholera RDTs. It highlights the need for fast, accurate, and easy-to-use tests for early outbreak detection in resource-limited settings. The document sets desired and acceptable
...
performance criteria, including high sensitivity and specificity, rapid results (under 15 minutes), and usability by non-laboratory personnel. The tests should be affordable, stable in extreme conditions, and require minimal training. The goal is to enhance cholera surveillance and outbreak response, ensuring quick containment and improved public health outcomes.
more
Cholera epidemics continue to be a major public health problem in many countries around the
world. When epidemics strike, they can spread rapidly. The disease can also evolve quickly;
patients with severe disease can die of dehydration hours after
...
showing the first symptoms of
cholera.
more
Small Baby (Teaching Videos)
recommended
Global Health Media Project
American Academy of Pediatrics (AAP); Essential Care for Small Babies (ECSB)
(2017)
Global Health Media Project developed the Small Baby Series to bring to life many life-saving practices such as how to keep premature babies warm with skin-to-skin care, and how to feed them with a cup or feeding tube before they’re strong enough
...
to breastfeed. The series consists of 27 short teaching videos. Five are designed specifically for mothers to demystify the needs of premature infants and help them care for their babies both in the hospital and at home
more
In this edition, medicines used in ICU, haemodialysis and chemotherapy unit has also been added under NEML. The medicines under disinfectants and antiseptics, intrauterine devices and barrier methods under contraceptives has been deleted and moved to medical supplies and equipment list. A section
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on traditional essential medicines list is also included at the end of the NEML
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WHO clinical guidelines.
For the first time, WHO has published guidelines to help (primarily) front-line healthcare providers give high-quality, compassionate, and respectful care to children and adolescents (up to age 18) who have or may have experienced sexual abuse, including sexual assault or r
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ape.
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Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups
recommended
Treating children infected with intestinal worms is one of the simplest and most cost–effective ways to improve their health.
The recommendations are intended for a wide audience, including policy-makers and their expert advisers as well as tech
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nical and programme staff at government institutions and organizations involved in the design, implementation and expansion of programmes to control soil-transmitted helminth infections.
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Oral Health and Dental Services
Plague: Knowledge resources for responders
recommended
Plague is a zoonotic disease caused by the bacteria Yersinia pestis, found in small mammals. It is transmitted between animals by their fleas.
The bacteria, the animal reservoir and the vector in a given area are collectively called a “plague natural focus”. Humans can become infected by bein
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g bitten by infected fleas direct contact with infected fluids or tissue from a host inhalation of respiratory droplet.
This channel aims to equip frontline responders with introductory level knowledge to manage outbreaks of plague.
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Drawing on lessons from recent events, WHO launched ‘PRET - Preparedness and Resilience for Emerging Threats’ to support countries in updating their pandemic plans. Building on the current global momentum, PRET applies a “mode of transmission lens.”
The first PRET module focuses on preparin
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g for respiratory pathogens. Future modules will focus on other pathogen groups such as arthropod-borne viruses.
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Cholera is an acute diarrhoeal infection caused by ingestion of contaminated water or food.
This introductory-level course has 4 sections and is intended for personnel responding to cholera outbreaks in complex emergencies or in settings where the basic environmental infrastructures have been damag
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ed or destroyed.
Section 1: Case definition and alerts for cholera. Section 2: Main transmission routes. Section 3: Key preventive actions. Section 4: Multisectoral cholera control strategy. We hope that this course will help you refresh what you already know and help you transform good principles on cholera management into action. Resources are attached to each section to dive further into this topic.
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Rapid Advice Guideline
This summary brief highlights key messages from the updated World Health Organization’s recommendation on tranexamic acid (TXA) for the treatment of postpartum haemorrhage (PPH), including policy and program implications for translating the TXA re
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commendation into action at the country level. In 2012, WHO published recommendations for the prevention and treatment of postpartum haemorrhage, including a recommendation on the use of TXA for treatment of PPH. The 2017 updated WHO Recommendation on TXA is based on new evidence on use of TXA for treatment of PPH. This summary brief is intended for policy-makers, programme managers, educators and providers.
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