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Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever Caused by a Newly Identified Virus Strain, Bundibugyo, Uganda, 2007–2008

Paul Roddy, Natasha Howard, Maria D. Van Kerkhove, et al. (2012) CC

PLoS ONE 7(12): e52986. doi:10.1371/journal.pone.0052986. Opern Access please download from the website

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The Burden of Pediatric Asthma

Ferrante, G.; La Grutta, S. Frontiers in Pediatrics (2018) CC

Asthma is the most common chronic disease in children, imposing a consistent burden on health system. In recent years, prevalence of asthma symptoms became globally increased in children and adolescents, particularly in Low-Middle Income Countries (LMICs). Host (genetics, atopy) and environmental fa... more

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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

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National clinical guidelines for managment of Diabetes mellitus

Republic of Kenya Ministry of Public Health and Sanitation (2010) CC

The prevalence of chronic non-communicable diseases such as diabetes, cardiovascular diseases and cancers has been on the increase in Kenya in the recent past. This has been occasioned by changes in social and demographic situation in the country. The life expectancy... more

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The reality of managing asthma in sub-Saharan Africa – Priorities and strategies for improving care

Mortimer, K.; Masekela, R.; Ozoh, O.; et al. (2022) CC2

Asthma is the most common non-communicable disease in children and remains one of the most common throughout the life course. The great majority of the burden of this disease is seen in low-income and middle-income countries (LMICs), which have disproportionately high asthma-related mortality relati... more

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Ambient air pollution and non-communicable respiratory illness in sub-Saharan Africa: a systematic review of the literature

Glenn, B. E.; Espira, L. M.; Larson, M. C.; Larson, P. S. BMC (2022) CC2

Aerosol pollutants are known to raise the risk of development of non-communicable respiratory diseases (NCRDs) such as asthma, chronic bronchitis, chronic obstructive pulmonary disease, and allergic rhinitis. Sub-Saharan Africa’s rapid pace of urbanization, economic expansion, and population growt... more

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Availability and Use of HIV Monitoring and Early Infant Diagnosis Technologies in WHO Member States in 2011–2013: Analysis of Annual Surveys at the Facility Level

V. Habiyambere; N. Ford; D. Low-Beer; et al. PLOS Medicine (2016) CC

PLOS Medicine | DOI:10.1371/journal.pmed.1002088 August 23, 2016

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Chapter 8 - Childhood Mental and Developmental Disorders (Mental, Neurological, and Substance Use Disorders: Disease Control Priorities)

J. G. Scott; C. Mihalopoulos; H. E. Erskine; et al. Mental, Neurological, and Substance Use Disorders: Disease Control Priorities, Third Edition (Volume 4). (2016) C2

Mental, Neurological, and Substance Use Disorders: Disease Control Priorities, Third Edition (Volume 4). Patel V, Chisholm D, Dua T, et al., editors. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2016 Mar 14.

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COMPENDIUM of health system responses to large-scale migration in the WHO European Region
recommended

World Health Organization WHO, Regional Office for Europe (2018) C_WHO

The scale of international migration in the WHO European Region has increased substantially in the last decade. The dynamics of large-scale migration pose specific challenges and opportunities to health systems, and responses will differ from country to country. Strengthening health system responses... more

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Water, Sanitation and Hygiene: Foundations of Development

Brocklehurst C. (2011) CC

The disease burden caused by poor water, sanitation and hygiene is significant. For instance, soil transmitted helminthes (hookworm, roundworm, ringworm) infest approximately two billion people. Shistosomiasis infects and debilitates 200 million people. Trachoma, a disease related to poor sanitation... more

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Communication in neglected Tropical Diseases' elimination: A scoping review and call for action

Nieto-Sanchez C., Hatley DM, Gijalva MJ., et al. (2022) CC

PLoS Negl Trop Dis 16(10): e0009774. Although the practice of communication is often called upon when intervening asn involgvingcommunties affected by NTD's, the disciplinary framewokr of healt communication research has been largely absent from NTD strategies. To illustrate how practices conceptual... more

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Packages of Care for Dementia in Low- and Middle-Income Countries

Prince; M.J.; D. Acosta; E. Castro-Costa, et al. PLOS Medicine (2009) CC

November 3, 2009https://doi.org/10.1371/journal.pmed.1000176 PLoS Med 6(11): e1000176. https://doi.org/10.1371/journal.pmed.1000176

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International technical guidance on sexuality education. An evidence-informed approach.

UNESCO (2018) CC

This revised and fully updated edition of the International technical guidance on sexuality education benefits from a new review of the current evidence, and reaffirms the position of sexuality education within a framework of human rights and gender equality. It promotes structured learning about... more

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Framework for Strengthening Integration of Mental Health in Programs for Children Orphaned or Made Vulnerable by HIV

4Children (2018) C1

Poverty, HIV and other disease burdens, coupled with common mental disorders including alcohol and other substance use disorders, posttraumatic stress disorder, clinical and postnatal depression, distress, and anxiety, impact how caregivers meet the needs of children. When mental health is not consi... more

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Study on the Gendered Impacts of Ebola in Liberia (February 2015)

Leena Kotilainen Finn Church Aid (2015)

This study examines the gendered impacts of the Ebola virus disease (EVD) in Liberia in the largest outbreak of EVD ever recorded. The findings are based on an extensive two-week desk study and one-week participatory field study conducted in January 2015 in the cities of Monrovia and Buchanan in Lib... more

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Introduction of DNA-based identification and typing methods to public health practitioners for epidemiological investigation of cholera outbreaks

Global Task Force on Cholera Control (GTFCC) World Health Organisation (WHO) (2017) C_WHO

The GTFCC Laboratory Support for Public Health Surveillance document provides guidelines on using DNA-based molecular techniques for identifying and monitoring Vibrio cholerae strains in cholera outbreaks. It highlights the importance of genetic sequencing for tracking transmission, detecting new va... more

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Association between Ambient Temperature and Hospitalization for Renal Diseases in Brazil during 2000–2015: A Nationwide Case-Crossover Study

Bo Wen, Rongbin Xu, Yao Wu, Micheline de Sousa Zanotti Stagliorio Coelho et al. The Lancet Regional Health – Americas (2021) CC

Climate change is increasing the risks of injuries, diseases, and deaths globally. However, the association between ambient temperature and renal diseases has not been fully characterized. This study aimed to quantify the risk and attributable burden for hospitalizations of renal diseases related to... more

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Insights into the Changing Perspectives of Multiple Sclerosis in India

L. Pandit Hindawi (2011) CC

SAGE-Hindawi Access to Research Autoimmune Diseases Volume 2011, Article ID 937586, 5 pages doi:10.4061/2011/937586

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Children of seasonal migrant workers

Bernard van Leer Foundation (2013) CC

Early Childhood Matters is a journal about early childhood. It looks at specific issues regarding the development of young children, in particular from a psychosocial perspective. It is published twice per year by the Bernard van Leer Foundation. The views expressed in Early Childhood Matters ... more

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Improving infection prevention and control at the health facility
recommended

World Health Organization WHO (2018) C_WHO

Interim practical manual supporting implementation of the WHO guidelines on core components of infection prevention and control programmes

COMPENDIUM of health system responses to large-scale migration in the WHO European Region recommended

Improving infection prevention and control at the health facility recommended

COMPENDIUM of health system responses to large-scale migration in the WHO European Region
recommended

Improving infection prevention and control at the health facility
recommended