Eur Respir J 2016; 48: 808–817 | DOI: 10.1183/13993003.00840-2016
Protocol and preliminary evaluationas of Jan 17, 2020
Advances in Infectious Diseases, 2015, 5, 57-62
Published Online March 2015 in SciRes.
This study aimed to understand the patterns of HIV drug resistance in pregnant women in Mozambique. This might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (pMTCT) and antenatal care.
The resources provide both the older as well as the updated Operational Guidelines for antiretroviral therapy centres, including administrative issues, functions and establishment of centres, reporting and recording tools, measures to improve retention in HIV care, supply chain management of drugs a...nd various other aspects that are essential to ensure quality treatment for people living with HIV/AIDS.
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Advance Copy
Accessed: 08.03.2020
Посттравматический стресс – это нормальная реакция на тяжелые травмирующие события.
В этом буклете рассматриваются признаки, симптомы и способы лечения ПТСР.
Anxiety disorders
Chapter F.2
Anxiety disorders
Chapter F.3
Практическое пособие для работодателей
Люди с РС не являются однородной группой; проявления заболевания значительно варьируются от человека к человеку. Тем не ме...нее, в их опыте есть много общего - например, усталость и колеблющееся течение болезни. По всему миру люди с МС продолжают работать, продвигаться по выбранной ими
карьерной стезе и оставаться профессионально активными.
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Geflüchtete Menschen sind vielfältigen psychosozialen Belastungen ausgesetzt. Um Versorgungs- und Präventionsbedarfe dieser Bevölkerungsgruppe niedrigschwellig und diversitätssensibel zu decken, werden vermehrt Peer-Ansätze verfolgt. Der vorliegende Beitrag informiert den Diskurs über die (We...iter-)Entwicklung und Implementierung von entsprechenden Angeboten für geflüchtete Menschen in Deutschland, indem zentrale Erkenntnisse aus der Prozessevaluation des präventiven Peer- Ansatzes „Mind-Spring“ (MS) nach Pilotierung in einem kommunalen Setting vorgestellt und diskutiert werden.
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March 9, 2021
Here you can find a collection of useful manuals, videos, infographics and resource platforms.
The category "Vaccine hesitancy & myths" will be updated regularly with new documents, videos and information material. Please check this category within the COVID-19
https://medbox.org/fi...lter/602505261716D/toolbox/vaccination-strategy#GO
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Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 117: e200460, 2022
Integrating the multiple dimensions of the problem into a coherent approach adapted to field realities and needs represents an immense challenge, but the payoff is more effective and sustainable experiences, with higher social awareness..., increased case detection and follow-up, improved adherence to care, and integrated participation of various actors from multiple action levels. Information, Education, and Communication (IEC) initiatives have great potential for impact in the implementation of multidimensional programs of prevention and control successfully customised to the diverse and complex contexts where Chagas disease persists.
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This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita...ls in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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PLOS Neglected Tropical Diseases 18(5): e0012091. https://doi.org/10.1371/journal.pntd.0012091
Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are... limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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