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Regulatory guidance for assessment and management of applications for marketing authorization of oxytocin

World Health Organization WHO (2021) C_WHO

Pharmaceutical regulators are at the forefront of ensuring that only safe and effective medicines are authorized and available in the market. This document builds on the recommendations in the above publication and has been prepared to specifically assist national medicines regulatory authorities to... more

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Ebola research and development landscape of clinical candidates and trials

World Health Organization (WHO) (2015) C_WHO

The report presents current information (updated to September 2015) on candidate vaccines, therapies and medical devices for Ebola and gives an overview of completed and on-going trials.

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Pathways to progress: a multi-level approach to strengthening health systems

Samuels, F., Amaya, A.B., Rodríguez Pose, R. and Balabanova, D. Overseas Development Institute (2014) C1

Findings on maternal and child health in Nepal, Mozambique and Rwanda, and neglected tropical diseases in Cambodia and Sierra Leone | This report synthesises findings from five country case studies from the health dimension of this project, which focus on maternal and child health (MCH) (Mozambique... more

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Minimum requirements for infection prevention and control programmes

World Health Organization WHO (2020) C_WHO

The purpose of this document is to present and promote the minimum requirements for IPC programmes at the national and health care facility level, identified by expert consensus according to available evidence and in the context of the WHO core components. The minimum requirements are defined as: I... more

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Toolkit on Mapping Legal, Health, and Social Services Responses to Child Maltreatment

World Health Organization; Lucerne University; Children Research Centre (2015)

The toolkit aims to provide researchers with guidance for improving the quality of studies that use administrative data to better ascertain child maltreatment incidence, response and service delivery. However, these are complex studies to conduct, and the toolkit is not meant to be comprehensive. Re... more

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People-centred framework for tuberculosis programme planning and prioritization, User guide

World Health Organization WHO (2019) C_WHO

The aim of the people-centred framework is to help countries to develop fully prioritized and budgeted NSPs based on a culture of making full use of the available data, which are aligned with national planning cycles and which provide the basis for a robust national response that can accelerate prog... more

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Strengthening countries’ capacities to adopt and adapt evidence-based guidelines: a handbook for guideline contextualization

World Health Organization WHO (2023) C_WHO

Trustworthy, evidence-based health guidelines form the basis of national policies affecting both patients and health-care workers. Emphasizing the link between robust evidence and people’s trust in their health systems, Dr Hans Henri P. Kluge, WHO Regional Director for Europe said at the launch ev... more

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Palliative care for older people: better practices

Hall, S.; H. Petkova, A.D. Tsouros, et al. World Health Organization WHO, Regional Office for Europe, et al. (2011) C_WHO

This publication aims to provide examples of better palliative care practices for older people to help those involved in planning and supporting care-oriented services most appropriately and effectively. Examples have been identifi ed from literature searches and from an international call... more

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Tuberculosis Research Funding Trends 2005-2020

World Health Organisation (WHO) (2021) C_WHO

Previous advocacy efforts have achieved tangible goals in terms garnering political commitments to increase financing for TB—as seen at the 2018 UN High-Level Meeting on TB. The challenge now is to ensure that these commitments are actually met within a global biomedical research ecosystem that... more

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Introducing and scaling up testing for human papillomavirus as part of a comprehensive programme for prevention and control of cervical cancer

World Health Organization WHO (2020) C_WHO

This guidance is intended to be used by programme managers following the decision to introduce human papillomavirus (HPV) virological testing as a screening assay in their national cervical cancer prevention and control programme. The guidance includes a step-by-step process to be followed after the... more

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Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infection and Interventions to Reduce Perinatal HIV Transmission in the United States

Development of Health and Human Services USA; AIDSinfo Development of Health and Human Services USA; AIDSinfo (2020) C2

Developed by the HHS Panel on Treatment of Pregnant Women with HIV Infection and Prevention of Perinatal Transmission— A Working Group of the Office of AIDS Research Advisory Council (OARAC) Accessed: 12.02.2020

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Laboratory Guidance for the Diagnosis of Ebola Virus Disease
recommended

World Health Organization (2014) C_WHO

Interim Recommendation published 19 September 2014. These recommendations reflect current understanding of Ebola virus disease (EVD) and are intended for national laboratory staff performing diagnostic testing to detect Ebola virus.

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Toolkit for developing a multisectoral action plan for noncommunicable diseases: overview 2022

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO

This toolkit is a "how to" guide for developing, implementing and evaluating a multisectoral action plan for prevention and control of NCDs. It is targeted at policy-makers, planners and programme managers, and is intended to help countries, provinces and cities meet the requirements for achieving g... more

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Toolkit for developing a multisectoral action plan for noncommunicable diseases: overview

World Health Organization (WHO) World Health Organization (WHO) (2022) C_WHO

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A System of Health Accounts 2011: Revised edition

Organisation for Economic Co-operation and Development (OECD), Eurostat and World Health Organization (WHO) OECD Publishing, Paris (2017) CC

A System of Health Accounts 2011: Revised Edition provides an updated and systematic description of the financial flows related to the consumption of health care goods and services. As demands for information increase and more countries implement and institutionalise health accounts according to the... more

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Africa’s Health Financing in a New Era

Africa Centres for Disease Control and Prevention (Africa CDC) (2025) CC

Africa’s health sector is facing an unprecedented financing crisis, driven by a sharp decline of 70% in Official Development Assistance (ODA) from 2021 to 2025 and deep-rooted structural vulnerabilities. This collapse is placing immense pressure on Africa’s already fragile health systems as ODA ...is seen as the backbone of critical health programs: pandemic preparedness, maternal and child health services, disease control programs are all at risk, threatening Sustainable Development Goal 3 and Universal Health Coverage. Compounding this is Africa’s spiraling debt, with countries expected to service USD 81 billion by 2025—surpassing anticipated external financing inflows—further eroding fiscal space for health investments. Level of domestic resources is low. TThe Abuja Declaration of 2001, a pivotal commitment made by African Union (AU) member states, aimed to reverse this trend by pledging to allocate at least 15% of national budgets to the health sector. However, more than two decades later, only three countries—Rwanda, Botswana, and Cabo Verde—have consistently met or exceeded this target (WHO, 2023). In contrast, over 30 AU member states remain well below the 10% benchmark, with some allocating as little as 5–7% of their national budgets to health. In addition, only 16 (29%) of African countries currently have updated versions of National Health Development Plan (NHDP) supported by a National Health Financing Plan (NHFP). These two documents play a critical role in driving internal resource mobilisation. At the same time, public health emergencies are surging, rising 41%—from 152 in 2022 to 213 in 2024—exposing severe under-resourcing of health infrastructure and workforce. Recurring outbreaks (Mpox, Ebola, cholera, measles, Marburg…) alongside effects of climate change and humanitarian crises in Eastern DRC, the Sahel, and Sudan, are overwhelming systems stretched by chronic underfunding. The situation is worsened by Africa’s heavy dependency with over 90% of vaccines, medicines, and diagnostics being externally sourced—leaving countries vulnerable to global supply chain shocks. Health worker shortages persist, with only 2.3 professionals per 1,000 people (below the WHO’s recommended 4.45), and fewer than 30% of systems are digitized, undermining disease surveillance and early warning. Without decisive action, Africa CDC projects the continent could reverse two decades of health progress, face 2 to 4 million additional preventable deaths annually, and a heightened risk of a pandemic emerging from within. Furthermore, 39 million more Africans could be pushed into poverty by 2030 due to intertwined health and economic shocks. This is not just a sectoral crisis—it is an existential threat to Africa’s political, social, and economic resilience, and global stability. In response, African leaders, under Africa CDC’s stewardship, are advancing a comprehensive three-pillar strategy centered on domestic resource mobilization, innovative financing, and blended finance. more

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Strategic Plan of Action and Budget 2016 – 2025 for Elimination of Onchocerciasis in Africa

World Health Organization WHO African Prgramme for Onchocerciasis Control (2012) C_WHO

The Strategic Plan of Action and Budget 2016-2025 for the elimination of onchocerciasisin countries was prepared based on the above dlrective for the consideration of IAF 18.The vision of the plan of action is to eliminate onchocerciasis in 80 percent of Africancountries. Implementation of the plan ... more

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Global consultation of National Leprosy Programme managers, partners and affected persons on Global Leprosy Strategy 2021–2030

World Health Organization WHO (2020) C_WHO

The World Health Organization organized a Consultation of National Leprosy Programme managers, partners and affected persons to discuss the draft Global Leprosy Strategy, 2021--2030. This virtual event took place from 26 to 30 October 2020. It was attended by more than 450 stakeholders. Contribution... more

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Ethics in epidemics, emergencies and disasters: research, surveillance and patient care: training manual

World Health Organization (WHO) (2015) C_WHO

Responses to epidemics, emergencies and disasters raise many ethical issues for the people involved, including public health specialists and policy makers. This training manual provides material on ethical issues in research, surveillance and patient care in these difficult contexts.

Laboratory Guidance for the Diagnosis of Ebola Virus Disease recommended

Laboratory Guidance for the Diagnosis of Ebola Virus Disease
recommended