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Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
The document “Communicable Disease Surveillance and Response Systems: A Guide to Planning” is a World Health Organization (WHO) guide designed to help countries develop and strengthen national surveillance and response systems for communicable diseases . It explains why surveillance is essential
...
for early detection of outbreaks, informed decision-making, and effective public health action, especially in the context of the revised International Health Regulations (2005).
The guide provides a structured approach to strategic and operational planning. It outlines how countries should assess their existing systems, define a vision and goals, identify expected key result areas (EKRAs), prioritize activities, set realistic targets, allocate resources, and monitor progress. It also includes practical tools such as templates, worksheets, and examples to support ministries of health in organizing planning workshops and developing multi-year strategic plans and annual operational plans. Overall, the document serves as a practical framework to improve preparedness, early warning, and response to public health emergencies.
more
Populations affected by emergencies are continually at risk of outbreaks of epidemic-prone diseases and other public health hazards. This operational guidance aims to guide decision-making on when and how to implement and strengthen Early Warning Alert and Response (EWAR) in preparation for and resp
...
onse to emergencies. Each module aims to provide updated operational guidance for EWAR practices, which may be more easily understood and applied during emergencies. Through its application, this operational guidance aims to contribute to:
- earlier detection of acute public health events
- earlier and more effective response
- reduced impact of emergencies on health
- increased trust of the population in the (public) health system
- fulfilling our collective commitments to the International Health Regulations (IHR,
2005).
This guidance was developed jointly by 69 experts from more than 20 organizations from global level to country level.
more
The document is a report by an expert group that presents a framework for improving future pandemic preparedness and emergency response, particularly in the context of India but with relevance to global health systems. It analyzes lessons learned from COVID-19 and past epidemics, identifies key weak
...
nesses in areas such as governance, surveillance, data management, research, and coordination, and proposes a comprehensive strategy to address them. The report emphasizes the importance of early detection, strong public health infrastructure, coordinated governance, scientific innovation, and international collaboration. A central idea is the ability to respond effectively within the first 100 days of an outbreak by having systems, resources, and policies already in place. Overall, it aims to strengthen resilience and ensure faster, more efficient responses to future health crises.
more
The text is a report from a WHO meeting that focuses on strengthening research in the field of health emergency and disaster risk management (Health EDRM). It describes how experts from different regions discussed current challenges, progress, and future priorities in improving research to better pr
...
epare for and respond to health emergencies and disasters. A central theme is the need for stronger collaboration between countries, institutions, and disciplines, as well as better use of evidence to support policies and decision-making. The report also outlines key actions, such as improving data sharing, developing practical guidance for policymakers, increasing research capacity—especially in low- and middle-income countries—and ensuring that research findings are effectively translated into real-world practice. Overall, the text emphasizes global cooperation and evidence-based strategies to enhance preparedness and resilience against health threats.
more
O documento apresenta o quadro da Organização Mundial da Saúde para a gestão de riscos de emergências de saúde e desastres (Health EDRM). Explica que comunidades em todo o mundo enfrentam uma ampla variedade de perigos — como surtos de doenças infecciosas, desastres naturais e conflitos —
...
e enfatiza a necessidade de uma abordagem abrangente e baseada no risco para reduzir seus impactos. O quadro descreve princípios fundamentais como prevenção, preparação, resposta e recuperação, e destaca a importância de sistemas de saúde fortes, colaboração multissetorial e envolvimento da comunidade. Também apresenta componentes centrais como desenvolvimento de políticas, coordenação, força de trabalho, comunicação e infraestrutura. De modo geral, o texto tem como objetivo ajudar os países a fortalecer a resiliência, reduzir riscos à saúde e melhorar sua capacidade de lidar com emergências de forma eficaz.
more
The document presents a strategic framework by the World Health Organization for managing risks related to emergencies and disasters in the health sector. It highlights that such events (such as epidemics, natural disasters, or conflicts) have major impacts on health, healthcare systems, and societa
...
l development. The framework proposes a comprehensive and proactive approach based on prevention, preparedness, response, and recovery, while emphasizing the importance of collaboration across different sectors and stakeholders. Its main objective is to reduce health risks, strengthen the resilience of communities and health systems, and improve health security at the global level.
more
El documento presenta un marco estratégico de la Organización Mundial de la Salud para la gestión de riesgos relacionados con emergencias y desastres en el sector de la salud. Destaca que estos eventos (como epidemias, desastres naturales o conflictos) tienen un impacto significativo en la salud,
...
los sistemas sanitarios y el desarrollo de la sociedad. El marco propone un enfoque integral y proactivo basado en la prevención, la preparación, la respuesta y la recuperación, al tiempo que subraya la importancia de la colaboración entre diferentes sectores y actores. Su objetivo principal es reducir los riesgos para la salud, fortalecer la resiliencia de las comunidades y los sistemas de salud, y mejorar la seguridad sanitaria a nivel mundial.
more
The GHEC framework is designed to provide guiding principles for standardizing health emergency workforce structures to strengthen the capacity of countries in responding to health emergencies, and to enhance collaboration between countries by better connecting regional and global surge response mec
...
hanisms, facilitating information exchange, and improving access to expertise and human response capacity at times of need.
This is the first version of the GHEC framework and is intended to be updated as experience is gained with its implementation and adaptation.
more
This report presents a WHO–PREZODE collaboration to develop and validate standardized indicators that assess the risk of zoonotic disease emergence by modeling pathogen circulation in animals and the risk of animal to human zoonotic spillover. The proposed indicators are intended to be actionable,
...
i.e., to reflect the impact of the implementation of a prevention strategy along the process of zoonotic pathogen emergence and over time.
more
As countries presented their epidemiological and programmatic situations, and WHO summarized the global status of HAT, the central message was one of satisfaction with the remarkable progress towards elimination. A historically low number of cases was reported, despite maintaining high levels of act
...
ive and passive screening in all accessible at-risk areas. In addition, 10 countries have been officially validated for the elimination of HAT as a public health problem.
Time was also devoted to reviewing progress and challenges in the areas of diagnostics, therapeutics and vector control interventions.
more
The 2026 appeal seeks nearly US$ 1 billion to respond to 36 emergencies worldwide, including 14 Grade 3 emergencies requiring the highest level of organizational response. These emergencies span sudden-onset and protracted humanitarian crises where health needs are critical.
Global consultation report Lyon, France 12-15 December 2023
The Government has declared a national emergency and three days of national mourning starting on 20 March. The official death toll from Cyclone Idai’s landfall has reportedly risen to at least 202 and is expected to increase in the days ahead.Flood waters are predicted to rise significantly in
...
the coming days and 350,000 people are at risk. The town of Buzi – home to 200,000 people – is at risk of becoming at least partially submerged.
more
Timely detection of novel coronavirus (2019-nCoV) infection cases is crucial to interrupt the spread of this virus. We assessed the required expertise and capacity for molecular detection of 2019-nCoV in specialised laboratories in 30 European Union/European Economic Area (EU/EEA) countries. Thirty-
...
eight laboratories in 24 EU/EEA countries had diagnostic tests available by 29 January 2020. A coverage of all EU/EEA countries was expected by mid-February. Availability of primers/probes, positive controls and personnel were main implementation barriers.
more
