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Publication Years
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Toolboxes
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Building true health security in a global age. Findings and recommendations of the Global Council. In landmark findings based on two years of research and convenings around the world, the new report shows that high levels of inequality are linked to outbreaks becoming pandemics and that inequality i
...
s undermining national and global responses, making pandemics more disruptive, deadly, and longer in duration. The report also shows that pandemics increase inequality, fuelling a cycle that research shows is visible not just for COVID-19, but also for AIDS, Ebola, Influenza, Mpox and beyond.
more
These guidelines update earlier WHO recommendations to maximize the HIV prevention impact of safe VMMC services and aim to guide the transition to the sustained provision of interventions with a focus on the health and well-being of both adolescent boys and men.
Data presentation is the basis for describing data and generating hypotheses for further testing. It consists of a number of methods for summarising data in order to support the identification of patterns. Data can be summarised in a number of forms, including tables or graphical representations s
...
uch as graphs or maps. Effective data presentation requires an understanding of the principles introduced in this guide.
more
WHO updated recommendations on HIV clinical management: recommendations for a public health approach
recommended
This document provides an overview of the updated World Health Organization recommendations for HIV clinical management, which focus on optimizing antiretroviral therapy, preventing vertical transmission, and enhancing tuberculosis prevention among individuals with HIV. These updates are intended to
...
support global initiatives aimed at ending AIDS as a public health threat by 2030. Key changes include the introduction of new antiretroviral drugs and regimens, revised postnatal prophylaxis and breastfeeding guidelines for managing infants at risk of vertical transmission, and the endorsement of shorter tuberculosis preventive treatments to improve efficacy and adherence.
more
Technical Brief
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
Dosing Recommendations for Prevention and Treatment
Archives of Medicine vo.7 no.5:10
Individuals infected with human immunodeficiency virus (HIV) often develop
multiple complications and comorbidities, among them, opportunistic infections.
The highest incidence of opportunistic infections was reported in the group
of patients with CD4 lymphocyte
...
levels below 200 cells / mm. Candidiasis,
toxoplasmosis and pneumocystis pneumonia (PCP) were the main representatives.
more
Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Early Warning and Response to Outbreaks and other Public Health Events: A Guide provides practical guidance for strengthening early warning functions within existing public health surveillance systems in WHO’s South-East Asia Region. The document explains how countries can detect, verify, and resp
...
ond rapidly to outbreaks and other unusual public health events in line with the International Health Regulations (2005). It describes the five key steps of an Early Warning and Response (EWAR) system—information collection, signal detection, event verification, response, and communication—and outlines how to set alert thresholds, identify signals, and ensure timely reporting. The guide also includes recommendations for monitoring and evaluating system performance to improve timeliness, sensitivity, and overall effectiveness in preventing and controlling public health threats.
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This report examines how clinical trials contribute to environmental impacts and outlines key considerations for integrating environmental sustainability into trial design, conduct and oversight. It explores the carbon footprint and resource use associated with clinical research activities – inclu
...
ding site operations, participant travel, supply chains, data management and waste – and highlights how these impacts intersect with climate change risks to health systems and research infrastructure.
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The document “Guidelines for the Investigation and Control of Disease Outbreaks” provides practical guidance for public health professionals on how to detect, investigate, and manage outbreaks of communicable diseases. It describes the key steps of outbreak investigation, including confirming th
...
e outbreak, establishing a case definition, collecting epidemiological and laboratory data, identifying the source and mode of transmission, and implementing control measures. The guidelines also explain how to organize outbreak response teams, communicate findings, and document results in outbreak reports. Overall, the document aims to support systematic and effective outbreak investigations in order to control disease spread and protect public health.
more
World Health Organization (2018). A practical guide for developing and conducting simulation exercises to test and validate pandemic influenza preparedness plans.
Southern African Journal of HIV Medicine
The document provides guidance from the CDC on conducting an Operational Readiness Review (ORR) within the Public Health Emergency Preparedness (PHEP) cooperative agreement. It outlines the purpose, structure, and evaluation criteria used to assess whether public health systems are prepared to respo
...
nd effectively to emergencies. The guidance describes required capabilities, review processes, and documentation expectations, helping jurisdictions demonstrate their readiness and identify areas for improvement in emergency preparedness and response.
more
BMC Public Health (2025) 25:3774 https://doi.org/10.1186/s12889-025-24555-6. The study results provide useful insights on how climate change influences malaria in African countries, and reiterates the need for a greater engagement of policymakers and social partners, in intensifying the action neede
...
d to fight the transmission of malaria in Sub-Sahara Africa
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Accessed 24 June 2014