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Les progrès remarquables réalisés dans la lutte contre la forme à T. b. gambiense reposent sur le dépistage et le traitement curatif, une stratégie qui interrompt la transmission en réduisant le réservoir de parasites chez l’être humain. Parfois, cette
approche a été combinée avec des
...
activités de lutte antivectorielle. L’objet de ces lignes directrices est donc de la plus haute importance pour la poursuite des progrès en vue de l’élimination de la THA.
more
The development of this target product profile (TPP) was led by the WHO Department of Control of Neglected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to id
...
entify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was formed, and different subgroups were created to advise on specific NTDs, including a subgroup working on the human African trypanosomiasis (HAT) diagnostic innovation needs. This group of independent experts included leading scientists, public health officials and endemic-country end-user representatives. Standard WHO Declaration of Interest procedures were followed. A landscape analysis of the available products and of the development pipeline was conducted, and the salient areas with unmet needs were identified.
more
Localized cutaneous leishmaniasis and its evolving forms (diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans), together with the sequela of visceral leishmaniasis (post-kala-azar dermal leishmaniasis), account for about one million cases of dermal leishmani
...
ases per year worldwide. Although not lethal, the dermal leishmaniases cause chronic, disfiguring skin lesions which are an important cause of morbidity and stigma.
more
Un comité OMS d’experts sur la trypanosomiase humaine africaine (THA) : lutte et surveillance, s’est réuni à Genève (Suisse), du 22 au 26 avril 2013. Le Dr H. Nakatani, sous-directeur général pour le VIH/SIDA, la tuberculose, le paludisme et les maladies tropicales négligées, a ouvert la
...
réunion au nom du Dr M. Chan, directeur-général de l’OMS.
La THA est une maladie qui afflige les populations rurales de l’Afrique, là où prolifère la mouche tsé-tsé (ou glossine), vecteur des trypanosomes qui en sont la cause. On distingue deux formes de THA : la forme à T. b. gambiense ou forme gambienne, endémique en Afrique de l’Ouest et en Afrique centrale et qui
représente actuellement 95 % des cas, et la forme à T. b. rhodesiense ou forme rhodésienne, endémique en Afrique de l’Est et en Afrique australe, à laquelle sont dus les 5 % restants.
more
La schistosomiase est une parasitose aiguë et chronique provoquée par des vers (trématodes) du genre Schistosoma. Selon les estimations, au moins 251,4 millions de personnes avaient besoin d’un traitement préventif en 2021. Le traitement préventif, qui devrait être renouvelé pendant un cert
...
ain nombre d’années, permettra de réduire et de prévenir la morbidité. La transmission de la schistosomiase est avérée dans 78 pays. Cependant, la chimioprophylaxie de la maladie, dont le but est de traiter à grande échelle les populations et les communautés, n’est nécessaire que dans 51 pays d’endémie où la transmission est de modérée à forte.
more
La esquistosomiasis es una enfermedad parasitaria aguda y crónica causada por duelas sanguíneas (trematodos) del género Schistosoma. Se calcula que al menos 251,4 millones de personas necesitaron tratamiento profiláctico en 2021. El tratamiento profiláctico, que se debería repetir durante algu
...
nos años, permite reducir y prevenir la morbilidad. Hay constancia de la transmisión de la enfermedad en 78 países. Sin embargo, la quimioprofilaxis para la esquistosomiasis, en la que se aplica un tratamiento a gran escala a personas y comunidades, solamente se requiere en 51 países en los que la enfermedad es endémica y tienen una transmisión de moderada a alta.
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داء البلهارسيات هو مرض طفيلي حاد ومزمن تسبّبه الديدان المثقوبة الدموية (المثقوبات) من جنس البلهارسية. وتشير التقديرات إلى أن 251.4 مليون شخص على الأقل كانوا بحاجة إلى
...
لعلاج الوقائي من داء البلهارسيات في عام 2021. ومن شأن العلاج الوقائي، الذي ينبغي تكراره على مدى عدة سنوات، أن يحد من المراضة ويمنعها. وقد أُبلغ عن سريان المرض في 78 بلداً. ومع ذلك، فإن العلاج الكيميائي الوقائي لداء البلهارسيات الذي يُستهدف فيه الأشخاص والمجتمعات المحلية بالعلاج على نطاق واسع، لا يلزم إلا في 51 بلداً موطوناً يشهد مستويات سريان المرض المتوسطة أو العالية.
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Шистосомоз является острой и хронической паразитарной болезнью, вызываемой кровяными сосальщиками (трематодными червями) из рода Schistosoma. В 2021 г. количество нуждаю
...
ихся в профилактическом лечении шистосомоза оценивалось на уровне не менее 251,4 млн человек. Профилактическое лечение, которое необходимо повторять через несколько лет, снижает и предотвращает заболеваемость шистосомозом. Передача шистосомоза регистрируется в 78 странах. Однако профилактическая химиотерапия в рамках широкомасштабного лечения шистосомоза среди людей и общин требуется только в 51 эндемичной стране с умеренными и высокими показателями передачи инвазии.
more
About a year after infection, a painful blister forms – 90% of the time on the lower leg – and one or more worms emerge accompanied by a burning sensation. To soothe the burning pain, patients often immerse the infected part of the body in water. The worm(s) then releases thousands of larvae (ba
...
by worms) into the water. These larvae reach the infective stage after being ingested by tiny crustaceans or copepods, also called water fleas.
more
Global efforts to eradicate dracunculiasis have continued to progress, with only 542 cases reported in 2012, as compared with 1058 in 2011. It is a long thread-like worm. It is transmitted exclusively when people drink water contaminated with parasite-infected water fl eas. It is now found in some o
...
f the most deprived regions of Africa.
more
Yaws is a chronic skin infection characterized by papillomas (noncancerous lumps) and ulcers. It is caused by the bacterium Treponema pallidum subspecies pertenue, which belongs to the same group of bacteria that causes venereal syphilis.
Yaws forms part of a group of chronic bacterial infections commonly known as the endemic treponematoses. These diseases are caused by spiral bacteria of the genus Treponema, which also includes endemic syphilis (bejel) and pinta. Yaws is the most common of these three infections.
Yaws is a disfiguring non-venereal disease caused by infection with the spirochaete. Treponema pallidum subspecies pertenue which is closely related to the causative agent of syphilis and those of the other endemic treponematoses, bejel and pinta. The disease is endemic in certain areas of the
...
World Health Organization (WHO) African, South-East Asia and Western Pacific regions. Of the neglected tropical diseases identified for elimination and eradication, yaws is one of two diseases targeted for eradication. In 1949, the Second World Health Assembly adopted resolution WHA2.36, which addresses yaws, bejel and pinta as major public health problems that need attention.
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In May the Sixty-sixth World Health Assembly adopted resolution WHA66.12 (1) on 17 neglected tropical diseases (NTDs). Among other measures, the resolution urges Member States to:
• ensure count
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ry ownership of prevention, control, elimination and eradication programmes;
• expand and implement interventions and advocate for predictable, long-term international financing for activities related to control and capacity strengthening;
• integrate control programmes into primary health-care services and existing programmes;
• ensure optimal programme management and implementation;
• achieve and maintain universal access to interventions and reach the targets of the roadmap.
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Course information
Yaws is targeted for eradication by WHO in the 2021-2030 NTD Roadmap. It is therefore crucial to know how to identify cases, design and implement activities to eradicate the disease at the community level.
In the context of inte
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gration of skin NTDs it is vital to learn to recognize a disease targeted for eradication. At the individual level yaws lesions may mimic other skin diseases. At the community level, it is key to know how to design and implement the total community treatment strategy and monitor its impact. This course aims at providing health workers with the basic knowledge to understand the epidemiology, diagnosis, treatment, impact, eradication strategy and reporting of yaws.
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Onchocerciasis used to be an important public health problem in Africa, with over 37 million people infected and millions suffering from debilitating skin disease, terrible itching, impaired vision and
blindness. But the epidemiological situation h
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as improved dramatically over the last two decades. Community directed treatment with ivermectin has effectively brought the disease under control in most endemic areas where onchocerciasis is no longer a public health risk.
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Onchocerciasis – or “river blindness” – is a parasitic disease caused by the filarial worm
Onchocerca volvulus. It is transmitted through the bites of infected blackflies (Simulium spp.) that
breed in fast-flowing rivers and streams, mostly in remote villages located near fertile land wher
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e
people rely on agriculture.
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Human echinococcosis is a zoonotic disease (a disease that is transmitted to humans from animals) that is caused by parasites, namely tapeworms of the genus Echinococcus.
An interregional meeting on leishmaniasis among neighbouring endemic
countries in the Eastern Mediterranean, African and European regions was organized by the World Health
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Organization (WHO) Regional Office for the Eastern
Mediterranean in Amman, Jordan, from 23 to 25 September 2018. The meeting was attended by representatives from the health ministries of Albania, Georgia, Greece, Iran (Islamic Republic of), Iraq, Jordan, Lebanon, Morocco, Pakistan, Saudi Arabia, Sudan, Syrian Arab Republic and Tunisia. Representatives from Afghanistan, Algeria and Libya were unable to attend. The Secretariat comprised staff from WHO headquarters, WHO regional offices in the Eastern Mediterranean, Africa and Europe, WHO country offices in Iraq, Pakistan, Syrian Arab Republic and Yemen, and WHO temporary advisors from Spain and Tunisia.
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WHO promotes the inclusion of foodborne trematodiases among the targets of preventive chemotherapy interventions. With the aim of providing access to quality medicines, WHO has negotiated with Novar
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tis Pharma AG whereby Novartis donates triclabendazole for the treatment of fascioliasis and paragonimiasis in endemic countries. WHO collects applications from ministries of health and medicines are shipped free of charge.
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