Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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Guidelines for the diagnosis and treatment of COVID-19 in intensive care units
DHS Working Papers No. 124
The 2018 NDHS is a national sample survey that provides up-to-date information on demographic and health indicators. The sample was selected using a stratified, two-stage cluster design, with enumeration areas (EAs) as the sampling units for the first stage. The second stage was a complete listing o...f households carried out in each of the 1,400 selected EAs. The target groups were women age 15-49 and men age 15-59
in randomly selected households across Nigeria. A representative sample of approximately 42,000 households was selected for the survey. One-third of the households (14,000) were selected for malaria, anaemia, and genotype testing of children age 6-59 months. Also, in the subsample of households selected
for the men’s survey, one eligible woman in each household was randomly selected for additional questions regarding domestic violence. Specifically, information was collected on fertility levels, marriage, fertility preferences, awareness and use of family planning methods, child feeding practices, nutritional status of women and children, adult and childhood mortality, awareness and attitudes regarding
HIV/AIDS, and female genital mutilation. The survey also assessed the nutritional status (according to weight and height measurements) of women and children in these households. In addition to presenting national estimates, the report provides estimates of key indicators for both rural and urban areas, the country’s six geopolitical zones and 36 states, and the Federal Capital Territory (FCT).
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Debido a la actual crisis socio-económica, política y de derechos humanos en Venezuela, cerca de 4.5 millones de personas han salido de su país; convirtiéndose en la segunda peor crisis migratoria del mundo, después de Siria. Se estima que más del 20% de los refugiados y migrantes son niños y... adolescentes. Cerca del 57% de los venezolanos en el exterior se encuentran en Ecuador, Colombia y Perú, según Naciones Unidas.
En 2018, Plan International decidió implementar una estrategia regional en Colombia, Ecuador y Perú para mejorar las condiciones de vida de los refugiados y migrantes venezolanos, durante sus etapas de tránsito y asentamiento.
Durante los meses de junio y julio de 2019, el equipo de la oficina regional visitó más de siete ciudades entre Colombia, Ecuador y Perú para escuchar los testimonios de los refugiados y migrantes, así como para analizar sus necesidades en materia de mecanismos de protección, prevención de la violencia y salud sexual y reproductiva.
El presente documento refleja algunas de las situaciones de riesgo y violencia a las que millones de venezolanos se enfrentan cada día, desde los testimonios y experiencias de 17 refugiados y migrantes.
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