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Full Perscribing information on Fexinidazole Tablet for oral use
INDICATIONS AND USAGE
Fexinidazole Tablets are indicated for the treatment of both the first-stage (hemolymphatic) and second-stage
...
(meningoencephalitic) human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in patients 6 years of age and older and weighing at least 20 kg.
Limitations of Use
Due to the decreased efficacy observed in patients with severe second stage HAT (cerebrospinal fluid white blood cell count (CSF-WBC) >100 cells/μL) due to T. brucei gambiense disease, Fexinidazole Tablets should only be used in these patients if there are no other available treatment options [see Warnings and Precautions (5.1)]
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In recent decades, India has witnessed a rapidly exploding epidemic of diabetes.
Indeed, India today has the second largest number of people with diabetes in the
world. The International Diabetes Federation (IDF) estimates that there are 72.9 million people with diabetes in India in 2017, which is
...
projected to rise to 134.3 million by the year 2045. The prevalence of diabetes in urban India, especially in large metropolitan cities has increased from 2% in the 1970s to over 20% at present and the rural areas are also fast catching up.
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The ICMR type 1 diabetes guidelines come at a time when the SARS-CoV-2 pandemic
has disproportionately affected people with diabetes population, exposing them to a
high risk for severe illness and mortality. Globally, diabetes was responsible for
...
over fourmillion deaths in the year 2019. It was the leading cause of end-stage kidney disease, adult-onset blindness and cardiovascular diseases. Further, there was a considerable heterogeneity in the prevalence of complications and deaths associated with diabetes across the countries.
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The Regional Child Protection Operational Note has been developed by IOM and UNICEF’s Regional and Country Offices in North, West and Central Afr
...
ica as a collaborative inter-agency and cross-regional endeavour within the framework of the sixth phase of the IOM Regional Development and Protection Programme (RDPP) for North Africa, a regional initiative funded by the European Union through the Directorate‑General for Migration and Home Affairs and the Italian Ministry of Interior.
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This research is one case in a study commissioned by the World Food Programme to investigate the participation of recipient community in the targeting and management of humanitarian food assistance in complex emergencies. The study involved a substa
...
ntial desk review of existing documentation, and three weeks of field work in February and March 2008. The purpose of the study was to understand the ways in which participatory or community-based approaches to targeting have been attempted, within the definition of community-based targeting suggested by WFP. The study was not an evaluation of targeting methods, although some critical examination of targeting was necessary in order to understand the constraints on community participation.
Related resources
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The Wits Justice Project
HIV Nursing Matters / page 30-33 / June 2015
Source: Guidelines for the Prevention and Treatment of HIV in Arrested, Detained and Sentenced Persons, 2008.
This study examines over 20 years of CBR implementation in Nepal. It includes an overview of CBR interventions, provides analysis of approaches and activities in terms of impact and sustainability
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and makes recommendations for future developments in CBR. This resource is useful for people interested in CBR in Nepal
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For handwashing to be effective, it needs to be practiced consistently and thoroughly. Even when people have access to soap and water, and know how
...
and why to wash their hands, many still do not properly wash their hands consistently at critical times. The handwashing behavior change challenge is not only to encourage people to wash their hands with soap, but to do so correctly and at all critical times.
Nudges are one example of a behavior change tool that can encourage people to wash their hands.
Although the evidence base for nudges is still emerging and nudges for handwashing have been tested primarily in single contexts or on a limited scale, this brief and infographic answer some frequently asked questions about nudges and provides examples of how they have been used in efforts to increase handwashing. more
Nudges are one example of a behavior change tool that can encourage people to wash their hands.
Although the evidence base for nudges is still emerging and nudges for handwashing have been tested primarily in single contexts or on a limited scale, this brief and infographic answer some frequently asked questions about nudges and provides examples of how they have been used in efforts to increase handwashing. more
Prepared as an outcome of ICMR Subcommittee on Gastric Cancer | This consensus document on Management of Gallbladder cancers summarizes the modalities of treatment including the site-specific anti-cancer therapies, supportive and palliative care
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and molecular markers and research questions. It also interweaves clinical, biochemical and epidemiological studies.
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This document is produced with the intent of strengthening the assessment mechanisms for the Ethiopian WASH cluster and to ensure data is available to identify needs (who, where, what, how many) and
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to inform response planning accordingly. It will present the existing data environment in the country and outline key steps in coordinating and planning assessments.
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Buruli ulcer (BU) is a bacterial skin infection that is caused by Mycobacterium ulcerans and mainly affects people who reside in the rural areas of Africa and in suburban
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and beach resort communities in Australia.
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Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and annually updated a global strategy for asthma management and prevention that has formed the basis for ma
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ny national guidelines. However, uptake of existing guidelines is poor. A major revision of the GINA report was published in 2014, and updated in 2015, reflecting an evolving understanding of heterogeneous airways disease, a broader evidence base, increasing interest in targeted treatment, and evidence about effective implementation approaches. During development of the report, the clinical utility of recommendations and strategies for their practical implementation were considered in parallel with the scientific evidence.
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During the reporting period, 5,068 people were identified as being displaced by conflict and in need of humanitarian aid. In addition, 434 people who were affected by conflict received humanitarian assistance across the north.
The European Resuscitation Council Guidelines for Resuscitation provide specific instructions for how resuscitation should be practiced and take into account ease of teaching and learning, as well a
...
s the science. They were developed by Europeans and have been specifically written with European practice in mind.
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A scale to measure (social) participation for use in rehabilitation, stigma reduction and social integration programmes
These guidelines were developed through an interagency process with participation by United Nations (UN) organiza-
tions, nongovernmental organizations, the International Red Cross and Red Crescent Movement
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and the International
Organization for Migration.
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The Minimum Standards for Protection Mainstreaming are a set of international standards designed to provide practical assistance to humanitarian actors to mainstream protection in the assessment, design, implementation, monitoring and evaluation of humanitarian programmes, projects
...
and activities. All humanitarian actors are expected to mainstream protection in their humanitarian assistance activities as a component of a broader commitment to quality and accountability in humanitarian response.
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The Sphere standards in national humanitarian response discussion paper sets out to understand and describe opportunities for adapting international humanitarian standards to a regional, national or local level in preparing for, or responding to a d
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isaster. The paper, which includes case studies and recommendations for humanitarian professionals, is available in English, French and Spanish
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El Niño conditions persisting during the 2015/16 planting season have caused the worst drought in 35 years in Southern Africa, resulting in a second consecutive failed harvest. This has created severe food shortages and compounded existing vulnerab
...
ilities. Since July 2016, Namibia and Botswana have declared national drought emergencies, in addition to the declarations made earlier by Lesotho, Malawi, Swaziland and Zimbabwe. Madagascar issued a letter of solidarity with the SADC Appeal, and Mozambique has maintained a red alert in affected areas.
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March - December 2018
The Government of Bangladesh has kept its borders open to Rohingya refugees and leads the humanitarian response. The people of Bangladesh continue to show tremendous generosity and
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hospitality in the face of a massive influx. In keeping with its policies, the Government of Bangladesh refers to the Rohingya as “Forcibly Displaced Myanmar Nationals”, in the present context. The UN system refers to this population as refugees, in line with the applicable international framework for protection and solutions, and the resulting accountabilities for the country of origin and asylum as well as the international community as a whole. In support of these efforts, the humanitarian community has rapidly scaled up its operations as well. Over a two-month period, the refugee population in Cox’s Bazar more than quadrupled.
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