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2
WHO guidelines for clinical management of arboviral diseases: dengue, chikungunya, Zika and yellow fever
recommended
The new WHO guidelines provide clinical management recommendations for four of the most widespread arboviruses affecting humans: dengue, chikungunya, Zika, and yellow fever.
An integrated approach is vital, as these four diseases often present with similar symptoms, especially in the early stages
...
of infection, and multiple arboviruses may circulate simultaneously in certain regions. This makes clinical differentiation challenging, particularly where diagnostic testing is not readily available.
This guideline is available in online format on the MAGICapp platform
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Growing emergencies and displacements across the world demand increasingly complex interventions and responses. The World Health Organization (WHO) has developed Malaria control in emergencies: a field manual to provide technical guidance to help partners respond effectively to malaria in emergency
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situations. This field manual supersedes the 2013 WHO handbook.
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The ongoing global pandemic of SARS-CoV-2 (Covid-19) poses unique diagnostic and clinical management challenges in regions where seasonal epidemic-prone diseases are endemic. Diseases such as dengue, malaria, seasonal influenza, leptospirosis, chikungunya, scrub typhus and bacterial infections often
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present with febrile syndromes that mimic or co-exist with SARS-CoV-2 infection, complicating diagnosis and treatment. This document provides guidelines for preventing, diagnosing and managing such co-infections. A high level of suspicion is essential during the monsoon and post-monsoon seasons, taking into account region-specific disease prevalence. While the WHO's case definition for SARS-CoV-2 is broad and sensitive, the need for parallel testing for co-infections, in accordance with the protocols of the MoHFW, ICMR, NVBDCP and NCDC, is necessitated by overlapping clinical features. Ensuring the availability of reliable rapid diagnostic kits and applying integrated clinical and laboratory approaches are crucial to improving patient outcomes in the context of concurrent infections.
Accessed on 26/08/2025.
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In line with the Defeating meningitis by 2030: a global road map, the WHO guidelines on meningitis diagnosis, treatment and care Executive Summary provides a summary of the evidence-based recommendations for the clinical management of children and adults with community-acquired meningitis, including
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acute and long-term care. Meningitis poses a significant public health threat, despite successful efforts to control the disease globally. The burden of morbidity and mortality from meningitis remains high, particularly in low- and middle-income countries and in settings experiencing large-scale, disruptive epidemics.
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The annual bulletin of the Mekong Malaria Elimination (MME) programme is a yearly report that reviews ongoing efforts to combat multidrug resistance and eliminate malaria in the 6 countries of the Greater Mekong subregion (GMS): Cambodia, China (Yunnan province), Lao People's Democratic Republic, My
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anmar, Thailand and Viet Nam.
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The 2024 World Malaria Report shows that the malaria burden remains overwhelmingly concentrated in Africa. The continent accounted for 94% of global cases and 95% of malaria-related deaths in 2023. Although the number of malaria cases increased globally from 204 million in 2000 to 246 million in 202
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3, the number of deaths declined from 805,000 to 569,000. Children under five are still the most affected group, accounting for 76% of malaria deaths in Africa. A few countries, particularly Nigeria and the Democratic Republic of the Congo, carry the highest burden. Since 2000, Africa has significantly reduced malaria incidence and mortality, averting over 1.7 billion cases and 12 million deaths. Nevertheless, malaria continues to pose a significant health challenge, necessitating ongoing action and investment.
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Health in All Policies (HiAP) promotes health and equity. It is based on the recognition that our greatest health challenges for example, non-communicable diseases, health inequities and inequalities, climate change, and spiraling health care costs are highly complex and often linked through the soc
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ial determinants of health (SDH). In this context, promoting healthy communities, and in particular health equity across different population groups, requires that we address the social determinants of health, such as public transportation, education access, access to healthy food, economic opportunities, and more. While many public policies work to achieve this, conflicts of interest may arise. Alternatively, unintended impacts of policies are not measured and addressed. This requires innovative solutions, and structures that build channels for dialogue and decision-making that work across traditional government policy siloes. Hence, HiAP could be adopted to ensure commitment from the highest decision makers within government to address the social determinants of health.
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PHSM are vital in reducing the risk and scale of infectious disease transmission and lowering hospitalization and deaths. Examples include contact tracing, quarantine and isolation, mask use, ventilation, school or workplace measures, mobility restrictions and travel requirements.
While these mea
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sures are essential, decision-making on PHSM becomes particularly complex during rapidly evolving health emergencies, with incomplete information and under significant public and political pressure, especially when the pathogen is novel or poorly understood. In such contexts, guidance needs to be agile and responsive, developed and adapted based on emerging evidence and shifting epidemiological patterns. Decision-makers are frequently confronted with difficult trade-offs, having to balance measures that are:
─ effective but socially disruptive;
─ cost-effective but logistically burdensome;
─ beneficial for public health but economically disruptive; or
─ practical but inequitable or unethical
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Ces questions fréquemment posées (FAQs) ont été élaborées par le Groupe de travail sur les maladies infectieuses du Groupe l'alimentation central sur des nourrissons en situation d'urgence (IFE) en se basant sur les recommandations les plus récentes, les connaissances collectives et les donn
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es probantes relatives au choléra. Les questions fréquemment posées (FAQs) s'appuient également sur les recommandations de l'Organisation mondiale de la santé (OMS) et du Groupe central sur l'alimentation des nourrissons en situation d'urgence (IFE CG) en matière d'alimentation des nourrissons et des jeunes enfants (IYCF). Ces FAQs ont pour objectif de fournir des réponses aux professionnels de santé ainsi qu’au grand public- y compris aux mères qui allaitent ou qui tirent leur lait- au sujet de l'allaitement maternel lors d'une épidémie de choléra.
Cesquestions fréquentesreflètent:
•Les preuves disponibles et les derniers outils de lutte contre le choléra du Groupe de travail mondial sur la lutte contre le choléra (2025) et de l'UNICEF (2013)
•Les effets protecteurs du lait maternel et de l'allaitement
•Les effets néfastes liés à l'utilisation inappropriée de substituts de lait maternel
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This document, with a focus on the built environment and health care facilities, intends to guide the audience in preparing for and responding to SARI pandemics caused by existing and novel pathogens. It provides technical guidance on designing, establishing, and managing health care facilities for
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severe acute respiratory infections (SARI), covering point of entry, treatment centers, entry to health system facilities, quarantine and community facilities, and home care and quarantine.
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With an estimated population of about 5 million and an annual growth rate of 8 per cent, Dar es Salaam, Tanzania, is Africa’s fastest growing city.1 Over 70 per cent of the people live in informal, unplanned settlements with inadequate infrastructure. In addition, heavy rainfalls twice a year
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result in signifi cant fl ood risks. The objectives in Dar es Salaam were to 1) obtain high quality and up to date exposure maps of aff ected communities and as a stretch goal 2) to create a hydrological model using elevation data. Both of these would form important elements to managing fl ood risks but neither had been previously available due to a lack of high quality digital imagery
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World malaria report 2025
recommended
Addressing the threat of antimalarial drug resistance. This year’s report spotlights the growing threat of antimalarial drug resistance. Partial resistance to artemisinin derivatives – the backbone of malaria treatments after failures of chloroquine and sulfadoxine-pyrimethamine – has now b
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een confirmed or suspected in at least 8 countries in Africa, and there are potential signs of declining efficacy of some of the drugs that are combined with artemisinin.
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Measles is one of the most contagious diseases for humans. It is caused by a paramyxovirus virus, manifesting as a febrile rash illness. The incubation period for measles usually is 10–14 days (range 7–23 days) from exposure to symptom onset. Initial symptoms (prodrome) generally consist of feve
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r, malaise, cough, conjunctivitis, and coryza. The characteristic maculopapular rash appears two to four days after onset of the prodrome. Patients are usually contagious from about four days before rash onset until four days after its appearance.
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In response to the growing necessity for accurate and timely information regarding deaths categorized by age, sex, and cause of death, underscored by the profound impact of the COVID-19 pandemic, the Africa Centres for Disease Control and Prevention (Africa CDC) developed the Continental Framework d
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esigned to fortify mortality surveillance within the African Union Member States. This Operational Guide is a comprehensive companion, delineating specific activities harmonized with the framework.
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В сводном руководстве изложены меры общественного здравоохранения применительно к ВИЧ-инфекции, вирусным гепатитам и инфекциям, передаваемым половым путем (ИПП
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П), для пяти следующих ключевых групп населения: мужчины, практикующие половые контакты с мужчинами; трансгендерные и гендерно разнообразные люди; секс-работники и работницы; люди, употребляющие инъекционные наркотики; люди, находящиеся в местах лишения свободы и других учреждениях закрытого типа.
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Polic brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for men who have sex with men.
Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
recommended
Panel on Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV
ClinicalInfo.gov
(2025)
C_CDC
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and
Adolescents With HIV document is published in an electronic format and updated as relevant changes
in prevention and treatment recommendations occur.
Archives of Medicine vo.7 no.5:10
Individuals infected with human immunodeficiency virus (HIV) often develop
multiple complications and comorbidities, among them, opportunistic infections.
The highest incidence of opportunistic infections was reported in the group
of patients with CD4 lymphocyte
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levels below 200 cells / mm. Candidiasis,
toxoplasmosis and pneumocystis pneumonia (PCP) were the main representatives.
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Topics in Antiviral Medicine, volume 33 Issue 2 May 2025
Currently, there are only two manufacturers with HIV POC diagnostic products prequalified by the World Health
Organization (WHO) and eligible for procurement through the United Nations. UNICEF concluded its last tender for
HIV EID and VL POC diagnostic technologies in 2018 and awarded two manufact
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urers long-term arrangements
(LTAs) to supply WHO prequalified product
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